Total synthesis and isolation of citrinalin and cyclopiamine congeners EV Mercado-Marin, P Garcia-Reynaga, S Romminger, EF Pimenta, ... Nature 509 (7500), 318-324, 2014 | 166 | 2014 |
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation AR Buller, S Brinkmann-Chen, DK Romney, M Herger, J Murciano-Calles, ... Proceedings of the National Academy of Sciences 112 (47), 14599-14604, 2015 | 158 | 2015 |
Enantioselective total synthesis of nigelladine A via late-stage C–H oxidation enabled by an engineered P450 enzyme SA Loskot, DK Romney, FH Arnold, BM Stoltz Journal of the American Chemical Society 139 (30), 10196-10199, 2017 | 117 | 2017 |
Unlocking reactivity of TrpB: a general biocatalytic platform for synthesis of tryptophan analogues DK Romney, J Murciano-Calles, JE Wehrmüller, FH Arnold Journal of the American Chemical Society 139 (31), 10769-10776, 2017 | 111 | 2017 |
Chemistry takes a bath: reactions in aqueous media DK Romney, FH Arnold, BH Lipshutz, CJ Li The Journal of organic chemistry 83 (14), 7319-7322, 2018 | 104 | 2018 |
Synthesis of β-branched tryptophan analogues using an engineered subunit of tryptophan synthase M Herger, P van Roye, DK Romney, S Brinkmann-Chen, AR Buller, ... Journal of the American Chemical Society 138 (27), 8388-8391, 2016 | 88 | 2016 |
A panel of TrpB biocatalysts derived from tryptophan synthase through the transfer of mutations that mimic allosteric activation J Murciano‐Calles, DK Romney, S Brinkmann‐Chen, AR Buller, ... Angewandte Chemie International Edition 55 (38), 11577-11581, 2016 | 74 | 2016 |
Catalyst control over regio-and enantioselectivity in Baeyer–Villiger oxidations of functionalized ketones DK Romney, SM Colvin, SJ Miller Journal of the American Chemical Society 136 (40), 14019-14022, 2014 | 72 | 2014 |
A Peptide-embedded trifluoromethyl ketone catalyst for enantioselective epoxidation DK Romney, SJ Miller Organic letters 14 (4), 1138-1141, 2012 | 64 | 2012 |
Improved Synthesis of 4-Cyanotryptophan and Other Tryptophan Analogues in Aqueous Solvent Using Variants of TrpB from Thermotoga maritima CE Boville, DK Romney, PJ Almhjell, M Sieben, FH Arnold The Journal of organic chemistry 83 (14), 7447-7452, 2018 | 57 | 2018 |
Aspartyl oxidation catalysts that dial in functional group selectivity, along with regio-and stereoselectivity JS Alford, NC Abascal, CR Shugrue, SM Colvin, DK Romney, SJ Miller ACS Central Science 2 (10), 733-739, 2016 | 41 | 2016 |
A synergistic combinatorial and chiroptical study of peptide catalysts for asymmetric Baeyer–Villiger oxidation MW Giuliano, CY Lin, DK Romney, SJ Miller, EV Anslyn Advanced synthesis & catalysis 357 (10), 2301-2309, 2015 | 40 | 2015 |
Nitroalkanes as versatile nucleophiles for enzymatic synthesis of noncanonical amino acids DK Romney, NS Sarai, FH Arnold ACS catalysis 9 (9), 8726-8730, 2019 | 35 | 2019 |
Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids AR Buller, S Brinkmann-Chen, M Herger, DK Romney, JM Calles, ... US Patent 10,513,719, 2019 | 7 | 2019 |
Beta-substituted non-canonical amino acids CE Boville, S Brinkmann-Chen, AR Buller, DK Romney, CK Prier, P Koch, ... US Patent 10,612,056, 2020 | 4 | 2020 |
Climbing Jacob's ladder DK Romney, SJ Miller Science 347 (6224), 829-829, 2015 | 3 | 2015 |
Method for the synthesis of tryptophan analogs in aqueous solvents at reduced temperatures CE Boville, DK Romney, PJ Almhjell, MM Sieben US Patent 10,752,927, 2020 | 1 | 2020 |
Directed evolution of artificial metalloenzymes: bridging synthetic chemistry and biology RK Zhang, DK Romney, SBJ Kan, FH Arnold Artificial Metalloenzymes and MetalloDNAzymes in Catalysis: From Design to …, 2018 | 1 | 2018 |
Engineered synthase for production of tryptophan derivatives and intransigent substrates DK Romney, JM Calles, JE Wehrmuller US Patent App. 18/530,082, 2024 | | 2024 |
Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids AR Buller, S Brinkmann-Chen, M Herger, DK Romney, JM Calles, ... US Patent 11,879,143, 2024 | | 2024 |