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David Romney
David Romney
Postdoctoral researcher, California Institute of Technology
在 caltech.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Total synthesis and isolation of citrinalin and cyclopiamine congeners
EV Mercado-Marin, P Garcia-Reynaga, S Romminger, EF Pimenta, ...
Nature 509 (7500), 318-324, 2014
1662014
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
AR Buller, S Brinkmann-Chen, DK Romney, M Herger, J Murciano-Calles, ...
Proceedings of the National Academy of Sciences 112 (47), 14599-14604, 2015
1582015
Enantioselective total synthesis of nigelladine A via late-stage C–H oxidation enabled by an engineered P450 enzyme
SA Loskot, DK Romney, FH Arnold, BM Stoltz
Journal of the American Chemical Society 139 (30), 10196-10199, 2017
1172017
Unlocking reactivity of TrpB: a general biocatalytic platform for synthesis of tryptophan analogues
DK Romney, J Murciano-Calles, JE Wehrmüller, FH Arnold
Journal of the American Chemical Society 139 (31), 10769-10776, 2017
1112017
Chemistry takes a bath: reactions in aqueous media
DK Romney, FH Arnold, BH Lipshutz, CJ Li
The Journal of organic chemistry 83 (14), 7319-7322, 2018
1042018
Synthesis of β-branched tryptophan analogues using an engineered subunit of tryptophan synthase
M Herger, P van Roye, DK Romney, S Brinkmann-Chen, AR Buller, ...
Journal of the American Chemical Society 138 (27), 8388-8391, 2016
882016
A panel of TrpB biocatalysts derived from tryptophan synthase through the transfer of mutations that mimic allosteric activation
J Murciano‐Calles, DK Romney, S Brinkmann‐Chen, AR Buller, ...
Angewandte Chemie International Edition 55 (38), 11577-11581, 2016
742016
Catalyst control over regio-and enantioselectivity in Baeyer–Villiger oxidations of functionalized ketones
DK Romney, SM Colvin, SJ Miller
Journal of the American Chemical Society 136 (40), 14019-14022, 2014
722014
A Peptide-embedded trifluoromethyl ketone catalyst for enantioselective epoxidation
DK Romney, SJ Miller
Organic letters 14 (4), 1138-1141, 2012
642012
Improved Synthesis of 4-Cyanotryptophan and Other Tryptophan Analogues in Aqueous Solvent Using Variants of TrpB from Thermotoga maritima
CE Boville, DK Romney, PJ Almhjell, M Sieben, FH Arnold
The Journal of organic chemistry 83 (14), 7447-7452, 2018
572018
Aspartyl oxidation catalysts that dial in functional group selectivity, along with regio-and stereoselectivity
JS Alford, NC Abascal, CR Shugrue, SM Colvin, DK Romney, SJ Miller
ACS Central Science 2 (10), 733-739, 2016
412016
A synergistic combinatorial and chiroptical study of peptide catalysts for asymmetric Baeyer–Villiger oxidation
MW Giuliano, CY Lin, DK Romney, SJ Miller, EV Anslyn
Advanced synthesis & catalysis 357 (10), 2301-2309, 2015
402015
Nitroalkanes as versatile nucleophiles for enzymatic synthesis of noncanonical amino acids
DK Romney, NS Sarai, FH Arnold
ACS catalysis 9 (9), 8726-8730, 2019
352019
Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids
AR Buller, S Brinkmann-Chen, M Herger, DK Romney, JM Calles, ...
US Patent 10,513,719, 2019
72019
Beta-substituted non-canonical amino acids
CE Boville, S Brinkmann-Chen, AR Buller, DK Romney, CK Prier, P Koch, ...
US Patent 10,612,056, 2020
42020
Climbing Jacob's ladder
DK Romney, SJ Miller
Science 347 (6224), 829-829, 2015
32015
Method for the synthesis of tryptophan analogs in aqueous solvents at reduced temperatures
CE Boville, DK Romney, PJ Almhjell, MM Sieben
US Patent 10,752,927, 2020
12020
Directed evolution of artificial metalloenzymes: bridging synthetic chemistry and biology
RK Zhang, DK Romney, SBJ Kan, FH Arnold
Artificial Metalloenzymes and MetalloDNAzymes in Catalysis: From Design to …, 2018
12018
Engineered synthase for production of tryptophan derivatives and intransigent substrates
DK Romney, JM Calles, JE Wehrmuller
US Patent App. 18/530,082, 2024
2024
Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids
AR Buller, S Brinkmann-Chen, M Herger, DK Romney, JM Calles, ...
US Patent 11,879,143, 2024
2024
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