Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ... New England journal of medicine 366 (20), 1905-1913, 2012 | 872 | 2012 |
STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia A Jerez, MJ Clemente, H Makishima, H Koskela, F LeBlanc, K Peng Ng, ... Blood, The Journal of the American Society of Hematology 120 (15), 3048-3057, 2012 | 454 | 2012 |
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ... Blood, The Journal of the American Society of Hematology 121 (22), 4541-4550, 2013 | 334 | 2013 |
STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients A Jerez, MJ Clemente, H Makishima, H Rajala, I Gómez-Seguí, T Olson, ... Blood, The Journal of the American Society of Hematology 122 (14), 2453-2459, 2013 | 177 | 2013 |
Immunosuppressive therapy of LGL leukemia: prospective multicenter phase II study by the Eastern Cooperative Oncology Group (E5998) TP Loughran Jr, L Zickl, TL Olson, V Wang, D Zhang, HLM Rajala, ... Leukemia 29 (4), 886, 2015 | 115 | 2015 |
The analysis of clonal diversity and therapy responses using STAT3 mutations as a molecular marker in large granular lymphocytic leukemia HLM Rajala, T Olson, MJ Clemente, S Lagström, P Ellonen, T Lundan, ... haematologica 100 (1), 91, 2015 | 107 | 2015 |
Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia E Andersson, H Kuusanmäki, S Bortoluzzi, S Lagström, A Parsons, ... Leukemia 30 (5), 1204-1208, 2016 | 94 | 2016 |
Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation EI Andersson, HLM Rajala, S Eldfors, P Ellonen, T Olson, A Jerez, ... Blood cancer journal 3 (12), e168-e168, 2013 | 83 | 2013 |
Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network BD Wang, CLB Kline, DM Pastor, TL Olson, B Frank, T Luu, AK Sharma, ... Molecular cancer 9, 1-19, 2010 | 79 | 2010 |
Vitamin D in hematological disorders and malignancies PM Kulling, KC Olson, TL Olson, DJ Feith, TP Loughran Jr European journal of haematology 98 (3), 187-197, 2017 | 74 | 2017 |
Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia P Savola, O Brück, T Olson, T Kelkka, MJ Kauppi, PE Kovanen, S Kytölä, ... haematologica 103 (2), 304, 2018 | 72 | 2018 |
Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines DM Pastor, LS Poritz, TL Olson, CL Kline, LR Harris III, WA Koltun, ... International journal of clinical and experimental medicine 3 (1), 69, 2010 | 63 | 2010 |
Identification of indels in next-generation sequencing data A Ratan, TL Olson, TP Loughran, W Miller BMC bioinformatics 16, 1-8, 2015 | 54 | 2015 |
IL-2 and IL-15 blockade by BNZ-1, an inhibitor of selective γ-chain cytokines, decreases leukemic T-cell viability TT Wang, J Yang, Y Zhang, M Zhang, S Dubois, KC Conlon, Y Tagaya, ... Leukemia 33 (5), 1243-1255, 2019 | 48 | 2019 |
TRAIL mediates and sustains constitutive NF-κB activation in LGL leukemia J Yang, FR LeBlanc, SA Dighe, CE Hamele, TL Olson, DJ Feith, ... Blood, The Journal of the American Society of Hematology 131 (25), 2803-2815, 2018 | 48 | 2018 |
Frequent somatic TET2 mutations in chronic NK-LGL leukemia with distinct patterns of cytopenias TL Olson, HJ Cheon, JC Xing, KC Olson, U Paila, CE Hamele, ... Blood, The Journal of the American Society of Hematology 138 (8), 662-673, 2021 | 45 | 2021 |
Vitamin D decreases STAT phosphorylation and inflammatory cytokine output in T-LGL leukemia KC Olson, PM Kulling, TL Olson, SF Tan, RJ Rainbow, DJ Feith, ... Cancer Biology & Therapy 18 (5), 290-303, 2017 | 36 | 2017 |
Genomic landscape of TCRαβ and TCRγδ T-large granular lymphocyte leukemia HJ Cheon, JC Xing, KB Moosic, J Ung, VW Chan, DS Chung, MF Toro, ... Blood, The Journal of the American Society of Hematology 139 (20), 3058-3072, 2022 | 35 | 2022 |
CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk C Baer, S Kimura, MS Rana, AB Kleist, T Flerlage, DJ Feith, P Chockley, ... Nature genetics 54 (5), 637-648, 2022 | 27 | 2022 |
Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer … KC Olson, PMK Larkin, R Signorelli, CE Hamele, TL Olson, MR Conaway, ... Cytokine 111, 551-562, 2018 | 25 | 2018 |