Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin MD Fullerton, S Galic, K Marcinko, S Sikkema, T Pulinilkunnil, ZP Chen, ... Nature medicine 19 (12), 1649-1654, 2013 | 895 | 2013 |
The ancient drug salicylate directly activates AMP-activated protein kinase SA Hawley, MD Fullerton, FA Ross, JD Schertzer, C Chevtzoff, KJ Walker, ... Science 336 (6083), 918-922, 2012 | 819 | 2012 |
Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis JD Crane, R Palanivel, EP Mottillo, AL Bujak, H Wang, RJ Ford, A Collins, ... Nature medicine 21 (2), 166-172, 2015 | 492 | 2015 |
MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis M Ouimet, HN Ediriweera, UM Gundra, FJ Sheedy, B Ramkhelawon, ... The Journal of clinical investigation 125 (12), 4334-4348, 2015 | 371 | 2015 |
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity S Galic, MD Fullerton, JD Schertzer, S Sikkema, K Marcinko, CR Walkley, ... The Journal of clinical investigation 121 (12), 4903-4915, 2011 | 369 | 2011 |
NOD1 activators link innate immunity to insulin resistance JD Schertzer, AK Tamrakar, JG Magalhães, S Pereira, PJ Bilan, ... Diabetes 60 (9), 2206-2215, 2011 | 292 | 2011 |
Defective NOD 2 peptidoglycan sensing promotes diet‐induced inflammation, dysbiosis, and insulin resistance E Denou, K Lolmède, L Garidou, C Pomie, C Chabo, TC Lau, ... EMBO molecular medicine 7 (3), 259-274, 2015 | 190 | 2015 |
Muramyl dipeptide-based postbiotics mitigate obesity-induced insulin resistance via IRF4 JF Cavallari, MD Fullerton, BM Duggan, KP Foley, E Denou, BK Smith, ... Cell metabolism 25 (5), 1063-1074. e3, 2017 | 183 | 2017 |
Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity RJ Ford, MD Fullerton, SL Pinkosky, EA Day, JW Scott, JS Oakhill, ... Biochemical Journal 468 (1), 125-132, 2015 | 179 | 2015 |
Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity SB Jorgensen, HM O’Neill, L Sylow, J Honeyman, KA Hewitt, R Palanivel, ... Diabetes 62 (1), 56-64, 2013 | 168 | 2013 |
Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance BD Henriksbo, TC Lau, JF Cavallari, E Denou, W Chi, JS Lally, JD Crane, ... Diabetes 63 (11), 3742-3747, 2014 | 163 | 2014 |
High intensity interval training improves liver and adipose tissue insulin sensitivity K Marcinko, SR Sikkema, MC Samaan, BE Kemp, MD Fullerton, ... Molecular metabolism 4 (12), 903-915, 2015 | 156 | 2015 |
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice HM O’Neill, JS Lally, S Galic, M Thomas, PD Azizi, MD Fullerton, BK Smith, ... Diabetologia 57, 1693-1702, 2014 | 148 | 2014 |
Metabolic and molecular aspects of ethanolamine phospholipid biosynthesis: the role of CTP: phosphoethanolamine cytidylyltransferase (Pcyt2) M Bakovic, MD Fullerton, V Michel Biochemistry and cell biology 85 (3), 283-300, 2007 | 138 | 2007 |
Mechanism of action of compound-13: an α1-selective small molecule activator of AMPK RW Hunter, M Foretz, L Bultot, MD Fullerton, M Deak, FA Ross, ... Chemistry & biology 21 (7), 866-879, 2014 | 129 | 2014 |
Developmental and metabolic effects of disruption of the mouse CTP: phosphoethanolamine cytidylyltransferase gene (Pcyt2) MD Fullerton, F Hakimuddin, M Bakovic Molecular and cellular biology, 2007 | 113 | 2007 |
The development of a metabolic disease phenotype in CTP: phosphoethanolamine cytidylyltransferase-deficient mice MD Fullerton, F Hakimuddin, A Bonen, M Bakovic Journal of Biological Chemistry 284 (38), 25704-25713, 2009 | 108 | 2009 |
Choline transport links macrophage phospholipid metabolism and inflammation SA Snider, KD Margison, P Ghorbani, ND LeBlond, C O'Dwyer, ... Journal of Biological Chemistry 293 (29), 11600-11611, 2018 | 99 | 2018 |
SIRT1 takes a backseat to AMPK in the regulation of insulin sensitivity by resveratrol MD Fullerton, GR Steinberg Diabetes 59 (3), 551, 2010 | 90 | 2010 |
Immunometabolism of AMPK in insulin resistance and atherosclerosis MD Fullerton, GR Steinberg, JD Schertzer Molecular and cellular endocrinology 366 (2), 224-234, 2013 | 89 | 2013 |