A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ... Cell stem cell 27 (1), 125-136. e7, 2020 | 675 | 2020 |
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, ... Nature 589 (7841), 270-275, 2021 | 482 | 2021 |
Long noncoding RNA lncKdm2b is required for ILC3 maintenance by initiation of Zfp292 expression B Liu, B Ye, L Yang, X Zhu, G Huang, P Zhu, Y Du, J Wu, X Qin, R Chen, ... Nature immunology 18 (5), 499-508, 2017 | 192 | 2017 |
IL-13 secreted by ILC2s promotes the self-renewal of intestinal stem cells through circular RNA circPan3 P Zhu, X Zhu, J Wu, L He, T Lu, Y Wang, B Liu, B Ye, L Sun, D Fan, ... Nature immunology 20 (2), 183-194, 2019 | 189 | 2019 |
The long non-coding RNA LncHDAC2 drives the self-renewal of liver cancer stem cells via activation of Hedgehog signaling J Wu, P Zhu, T Lu, Y Du, Y Wang, L He, B Ye, B Liu, L Yang, J Wang, Y Gu, ... Journal of hepatology 70 (5), 918-929, 2019 | 111 | 2019 |
LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis P Zhu, J Wu, Y Wang, X Zhu, T Lu, B Liu, L He, B Ye, S Wang, S Meng, ... Nature cell biology 20 (10), 1134-1144, 2018 | 108 | 2018 |
Human organoid models to study SARS-CoV-2 infection Y Han, L Yang, LA Lacko, S Chen Nature Methods 19 (4), 418-428, 2022 | 102 | 2022 |
Identification of candidate COVID-19 therapeutics using hPSC-derived lung organoids Y Han, L Yang, X Duan, F Duan, BE Nilsson-Payant, TM Yaron, P Wang, ... BioRxiv, 2020.05. 05.079095, 2020 | 97 | 2020 |
LncKdm2b controls self‐renewal of embryonic stem cells via activating expression of transcription factor Zbtb3 B Ye, B Liu, L Yang, X Zhu, D Zhang, W Wu, P Zhu, Y Wang, S Wang, ... The EMBO journal 37 (8), e97174, 2018 | 79 | 2018 |
SARS-CoV-2 infection induces ferroptosis of sinoatrial node pacemaker cells Y Han, J Zhu, L Yang, BE Nilsson-Payant, R Hurtado, LA Lacko, X Sun, ... Circulation research 130 (7), 963-977, 2022 | 66 | 2022 |
An inducible circular RNA circKcnt2 inhibits ILC3 activation to facilitate colitis resolution B Liu, B Ye, X Zhu, L Yang, H Li, N Liu, P Zhu, T Lu, L He, Y Tian, Z Fan Nature communications 11 (1), 4076, 2020 | 61 | 2020 |
SARS-CoV-2 infection causes dopaminergic neuron senescence L Yang, TW Kim, Y Han, MS Nair, O Harschnitz, J Zhu, P Wang, SY Koo, ... Cell Stem Cell 31 (2), 196-211. e6, 2024 | 56 | 2024 |
An immuno-cardiac model for macrophage-mediated inflammation in COVID-19 hearts L Yang, Y Han, F Jaffre, BE Nilsson-Payant, Y Bram, P Wang, J Zhu, ... Circulation research 129 (1), 33-46, 2021 | 53 | 2021 |
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2 L Yang, BE Nilsson-Payant, Y Han, F Jaffré, J Zhu, P Wang, T Zhang, ... Stem cell reports 16 (9), 2274-2288, 2021 | 48 | 2021 |
Modeling COVID-19 with human pluripotent stem cell-derived cells reveals synergistic effects of anti-inflammatory macrophages with ACE2 inhibition against SARS-CoV-2 F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Payant, P Wang, ... Research square, 2020 | 45 | 2020 |
Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice B Ye, B Liu, L Hao, X Zhu, L Yang, S Wang, P Xia, Y Du, S Meng, ... Nature communications 9 (1), 1261, 2018 | 43 | 2018 |
Circular RNA circZbtb20 maintains ILC3 homeostasis and function via Alkbh5-dependent m6A demethylation of Nr4a1 mRNA B Liu, N Liu, X Zhu, L Yang, B Ye, H Li, P Zhu, T Lu, Y Tian, Z Fan Cellular & Molecular Immunology 18 (6), 1412-1424, 2021 | 37 | 2021 |
Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2 B Ye, B Liu, L Yang, G Huang, L Hao, P Xia, S Wang, Y Du, X Qin, P Zhu, ... Nature communications 8 (1), 1518, 2017 | 35 | 2017 |
Modulating the transcriptional landscape of SARS-CoV-2 as an effective method for developing antiviral compounds DA Hoagland, DJB Clarke, R Møller, Y Han, L Yang, ML Wojciechowicz, ... Biorxiv, 2020.07. 12.199687, 2020 | 29 | 2020 |
IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development B Liu, B Ye, X Zhu, G Huang, L Yang, P Zhu, Y Du, J Wu, S Meng, Y Tian, ... Nature Communications 8 (1), 231, 2017 | 28 | 2017 |