| TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS CH Yu, S Davidson, CR Harapas, JB Hilton, MJ Mlodzianoski, ... Cell 183 (3), 636-649. e18, 2020 | 592 | 2020 |
| Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 408 | 2020 |
| TBK1 and IKKε act redundantly to mediate STING-induced NF-κB responses in myeloid cells KR Balka, C Louis, TL Saunders, AM Smith, DJ Calleja, DB D’Silva, ... Cell reports 31 (1), 2020 | 275 | 2020 |
| Stressing out the mitochondria: Mechanistic insights into NLRP3 inflammasome activation M Yabal, DJ Calleja, DS Simpson, KE Lawlor Journal of leukocyte biology 105 (2), 377-399, 2019 | 91 | 2019 |
| Understanding SOCS protein specificity EM Linossi, DJ Calleja, SE Nicholson Growth Factors 36 (3-4), 104-117, 2018 | 50 | 2018 |
| Inhibitors of sars-cov-2 plpro DJ Calleja, G Lessene, D Komander Frontiers in chemistry 10, 876212, 2022 | 49 | 2022 |
| Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24 S Davidson, CH Yu, A Steiner, F Ebstein, PJ Baker, V Jarur-Chamy, ... Science immunology 7 (68), eabi6763, 2022 | 38 | 2022 |
| Insights into drug Repurposing, as well as specificity and compound properties of piperidine-based SARS-CoV-2 PLpro inhibitors DJ Calleja, N Kuchel, BGC Lu, RW Birkinshaw, T Klemm, M Doerflinger, ... Frontiers in Chemistry 10, 861209, 2022 | 19 | 2022 |
| NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity J Moecking, P Laohamonthonkul, K Chalker, MJ White, CR Harapas, ... Journal of Allergy and Clinical Immunology 147 (6), 2134-2145. e20, 2021 | 18 | 2021 |
| Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands EM Linossi, K Li, G Veggiani, C Tan, F Dehkhoda, C Hockings, DJ Calleja, ... Nature Communications 12 (1), 7032, 2021 | 9 | 2021 |
| Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii ML Wilde, U Ruparel, T Klemm, VV Lee, DJ Calleja, D Komander, ... Life Science Alliance 6 (6), 2023 | 2 | 2023 |
| Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape X Wu, M Go, JV Nguyen, NW Kuchel, BGC Lu, K Zeglinski, KN Lowes, ... Nature Communications 15 (1), 6219, 2024 | | 2024 |
| Mutational Profiling of SARS-CoV-2 PLpro in human cells reveals requirements for function, structure, and drug escape X Wu, M Go, JV Nguyen, NW Kuchel, BGC Lu, KN Lowes, DJ Calleja, ... bioRxiv, 2024.03. 11.584210, 2024 | | 2024 |
| Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands (vol 4, 7951, 2023) EM Linossi, K Li, G Veggiani, C Tan, F Dehkhoda, C Hockings, DJ Calleja, ... NATURE COMMUNICATIONS 14 (1), 2023 | | 2023 |
| Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands EM Linossi, K Li, G Veggiani, C Tan, F Dehkhoda, C Hockings, DJ Calleja, ... nature communications 14, 2023 | | 2023 |
| Mechanism and inhibition of SARS-CoV-2 PLpro (preprint) T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... | | 2020 |
