Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease H Kvartsberg, FH Duits, M Ingelsson, N Andreasen, A Öhrfelt, ... Alzheimer's & Dementia 11 (10), 1180-1190, 2015 | 340 | 2015 |
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative TK Karikari, AL Benedet, NJ Ashton, J Lantero Rodriguez, A Snellman, ... Molecular psychiatry 26 (2), 429-442, 2021 | 252 | 2021 |
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology E Portelius, B Olsson, K Höglund, NC Cullen, H Kvartsberg, ... Acta neuropathologica 136, 363-376, 2018 | 169 | 2018 |
Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease JB Pereira, S Janelidze, R Ossenkoppele, H Kvartsberg, A Brinkmalm, ... Brain 144 (1), 310-324, 2021 | 165 | 2021 |
Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease K Hellwig, H Kvartsberg, E Portelius, U Andreasson, TJ Oberstein, ... Alzheimer's research & therapy 7, 1-8, 2015 | 141 | 2015 |
Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer’s disease patients and healthy controls H Kvartsberg, E Portelius, U Andreasson, G Brinkmalm, K Hellwig, ... Alzheimer's research & therapy 7, 1-9, 2015 | 133 | 2015 |
Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation P Bergström, L Agholme, FH Nazir, TM Satir, J Toombs, H Wellington, ... Scientific reports 6 (1), 29200, 2016 | 99 | 2016 |
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain I Alić, PA Goh, A Murray, E Portelius, E Gkanatsiou, G Gough, KY Mok, ... Molecular psychiatry 26 (10), 5766-5788, 2021 | 96 | 2021 |
Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology K Blennow, C Chen, C Cicognola, KR Wildsmith, PT Manser, ... Brain 143 (2), 650-660, 2020 | 84 | 2020 |
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease H Kvartsberg, T Lashley, CE Murray, G Brinkmalm, NC Cullen, K Höglund, ... Acta Neuropathologica 137, 89-102, 2019 | 84 | 2019 |
Phenotypic screening identifies modulators of amyloid precursor protein processing in human stem cell models of Alzheimer’s disease PW Brownjohn, J Smith, E Portelius, L Serneels, H Kvartsberg, ... Stem cell reports 8 (4), 870-882, 2017 | 69 | 2017 |
CSF synaptic biomarkers in the preclinical stage of Alzheimer disease and their association with MRI and PET: a cross-sectional study M Mila-Aloma, A Brinkmalm, NJ Ashton, H Kvartsberg, M Shekari, ... Neurology 97 (21), e2065-e2078, 2021 | 52 | 2021 |
Evaluation of a novel immunoassay to detect p-tau Thr217 in the CSF to distinguish Alzheimer disease from other dementias J Hanes, A Kovac, H Kvartsberg, E Kontsekova, L Fialova, S Katina, ... Neurology 95 (22), e3026-e3035, 2020 | 47 | 2020 |
Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase B Becker, FH Nazir, G Brinkmalm, E Camporesi, H Kvartsberg, E Portelius, ... Molecular neurodegeneration 13, 1-12, 2018 | 33 | 2018 |
Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration K Höglund, N Schussler, H Kvartsberg, U Smailovic, G Brinkmalm, ... Neurobiology of disease 134, 104645, 2020 | 23 | 2020 |
Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decline and other dementias C Cicognola, O Hansson, P Scheltens, H Kvartsberg, H Zetterberg, ... Alzheimer's Research & Therapy 13, 1-12, 2021 | 19 | 2021 |
Neurogranin in Alzheimer's disease and ageing: A human post-mortem study T Saunders, C Gunn, K Blennow, H Kvartsberg, H Zetterberg, SD Shenkin, ... Neurobiology of disease 177, 105991, 2023 | 16 | 2023 |
Amyloid pathology and synaptic loss in pathological aging E Gkanatsiou, J Nilsson, CE Toomey, A Vrillon, H Kvartsberg, E Portelius, ... Journal of Neurochemistry 159 (2), 258-272, 2021 | 14 | 2021 |
Are neuropsychiatric symptoms in dementia linked to CSF biomarkers of synaptic and axonal degeneration? V Bloniecki, H Zetterberg, D Aarsland, P Vannini, H Kvartsberg, B Winblad, ... Alzheimer's Research & Therapy 12, 1-10, 2020 | 14 | 2020 |
A novel ultrasensitive assay for plasma p‐tau217: performance in individuals with subjective cognitive decline and early Alzheimer's disease F Gonzalez‐Ortiz, PCL Ferreira, A González‐Escalante, L Montoliu‐Gaya, ... Alzheimer's & Dementia 20 (2), 1239-1249, 2024 | 12 | 2024 |