| Targeting the phosphoinositide 3-kinase pathway in cancer P Liu, H Cheng, TM Roberts, JJ Zhao Nature reviews Drug discovery 8 (8), 627-644, 2009 | 3173 | 2009 |
| COT drives resistance to RAF inhibition through MAP kinase pathway reactivation CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ... Nature 468 (7326), 968-972, 2010 | 1725 | 2010 |
| PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting LM Thorpe, H Yuzugullu, JJ Zhao Nature Reviews Cancer 15 (1), 7-24, 2015 | 1398 | 2015 |
| Formation of mRNA 3′ ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis J Zhao, L Hyman, C Moore Microbiology and molecular biology reviews 63 (2), 405-445, 1999 | 1292 | 1999 |
| CDK4/6 inhibition triggers anti-tumour immunity S Goel, MJ DeCristo, AC Watt, H BrinJones, J Sceneay, BB Li, N Khan, ... Nature 548 (7668), 471-475, 2017 | 1217 | 2017 |
| Essential roles of PI (3) K–p110β in cell growth, metabolism and tumorigenesis S Jia, Z Liu, S Zhang, P Liu, L Zhang, SH Lee, J Zhang, S Signoretti, ... Nature 454 (7205), 776-779, 2008 | 856 | 2008 |
| Integrative genomic approaches identify IKBKE as a breast cancer oncogene JS Boehm, JJ Zhao, J Yao, SY Kim, R Firestein, IF Dunn, SK Sjostrom, ... Cell 129 (6), 1065-1079, 2007 | 713 | 2007 |
| A genetic screen for candidate tumor suppressors identifies REST TF Westbrook, ES Martin, MR Schlabach, Y Leng, AC Liang, B Feng, ... Cell 121 (6), 837-848, 2005 | 591 | 2005 |
| PARP inhibition elicits STING-dependent antitumor immunity in Brca1-deficient ovarian cancer L Ding, HJ Kim, Q Wang, M Kearns, T Jiang, CE Ohlson, BB Li, S Xie, ... Cell reports 25 (11), 2972-2980. e5, 2018 | 454 | 2018 |
| A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells TR Kau, F Schroeder, S Ramaswamy, CL Wojciechowski, JJ Zhao, ... Cancer cell 4 (6), 463-476, 2003 | 452 | 2003 |
| Overcoming therapeutic resistance in HER2-positive breast cancers with CDK4/6 inhibitors S Goel, Q Wang, AC Watt, SM Tolaney, DA Dillon, W Li, S Ramm, ... Cancer cell 29 (3), 255-269, 2016 | 440 | 2016 |
| CDK7-dependent transcriptional addiction in triple-negative breast cancer Y Wang, T Zhang, N Kwiatkowski, BJ Abraham, TI Lee, S Xie, H Yuzugullu, ... Cell 163 (1), 174-186, 2015 | 435 | 2015 |
| Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma HS Venkatesh, LT Tam, PJ Woo, J Lennon, S Nagaraja, SM Gillespie, J Ni, ... Nature 549 (7673), 533-537, 2017 | 424 | 2017 |
| Bioprinting for cancer research S Knowlton, S Onal, CH Yu, JJ Zhao, S Tasoglu Trends in biotechnology 33 (9), 504-513, 2015 | 419 | 2015 |
| The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells JJ Zhao, Z Liu, L Wang, E Shin, MF Loda, TM Roberts Proceedings of the National Academy of Sciences 102 (51), 18443-18448, 2005 | 402 | 2005 |
| CDK4/6 inhibition in cancer: beyond cell cycle arrest S Goel, MJ DeCristo, SS McAllister, JJ Zhao Trends in cell biology 28 (11), 911-925, 2018 | 401 | 2018 |
| Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase JJ Zhao, OV Gjoerup, RR Subramanian, Y Cheng, W Chen, TM Roberts, ... Cancer cell 3 (5), 483-495, 2003 | 350 | 2003 |
| Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast MM Kessler, MF Henry, E Shen, J Zhao, S Gross, PA Silver, CL Moore Genes & development 11 (19), 2545-2556, 1997 | 309 | 1997 |
| Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms P Liu, H Cheng, S Santiago, M Raeder, F Zhang, A Isabella, J Yang, ... Nature medicine 17 (9), 1116-1120, 2011 | 296 | 2011 |
| The p110α isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation JJ Zhao, H Cheng, S Jia, L Wang, OV Gjoerup, A Mikami, TM Roberts Proceedings of the National Academy of Sciences 103 (44), 16296-16300, 2006 | 267 | 2006 |
