PLGA nanoparticles for oral delivery of cyclosporine: nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral® JL Italia, DK Bhatt, V Bhardwaj, K Tikoo, MNVR Kumar Journal of Controlled Release 119 (2), 197-206, 2007 | 266 | 2007 |
Age‐and genotype‐dependent variability in the protein abundance and activity of six major uridine diphosphate‐glucuronosyltransferases in human liver DK Bhatt, A Mehrotra, A Gaedigk, R Chapa, A Basit, H Zhang, ... Clinical Pharmacology & Therapeutics 105 (1), 131-141, 2019 | 104 | 2019 |
Differential effects of tannic acid on cisplatin induced nephrotoxicity in rats K Tikoo, DK Bhatt, AB Gaikwad, V Sharma, DG Kabra FEBS letters 581 (10), 2027-2035, 2007 | 93 | 2007 |
Age-dependent absolute abundance of hepatic carboxylesterases (CES1 and CES2) by LC-MS/MS proteomics: application to PBPK modeling of oseltamivir in vivo pharmacokinetics in … M Boberg, M Vrana, A Mehrotra, RE Pearce, A Gaedigk, DK Bhatt, ... Drug Metabolism and Disposition 45 (2), 216-223, 2017 | 86 | 2017 |
Abundance of phase 1 and 2 drug-metabolizing enzymes in alcoholic and hepatitis C cirrhotic livers: a quantitative targeted proteomics study B Prasad, DK Bhatt, K Johnson, R Chapa, X Chu, L Salphati, G Xiao, ... Drug Metabolism and Disposition 46 (7), 943-952, 2018 | 79 | 2018 |
Nitric oxide synthase, calcitonin gene-related peptide and NK-1 receptor mechanisms are involved in GTN-induced neuronal activation R Ramachandran, DK Bhatt, KB Ploug, A Hay-Schmidt, I Jansen-Olesen, ... Cephalalgia 34 (2), 136-147, 2014 | 72 | 2014 |
PBDEs altered gut microbiome and bile acid homeostasis in male C57BL/6 mice CY Li, JL Dempsey, D Wang, SW Lee, KM Weigel, Q Fei, DK Bhatt, ... Drug Metabolism and Disposition 46 (8), 1226-1240, 2018 | 71 | 2018 |
Critical issues and optimized practices in quantification of protein abundance level to determine interindividual variability in DMET proteins by LC‐MS/MS proteomics DK Bhatt, B Prasad Clinical Pharmacology & Therapeutics 103 (4), 619-630, 2018 | 71 | 2018 |
PACAP-38 infusion causes sustained vasodilation of the middle meningeal artery in the rat: possible involvement of mast cells DK Bhatt, S Gupta, J Olesen, I Jansen-Olesen Cephalalgia 34 (11), 877-886, 2014 | 64 | 2014 |
A naturalistic glyceryl trinitrate infusion migraine model in the rat R Ramachandran, DK Bhatt, KB Ploug, J Olesen, I Jansen-Olesen, ... Cephalalgia 32 (1), 73-84, 2012 | 58 | 2012 |
Hepatic abundance and activity of androgen-and drug-metabolizing enzyme UGT2B17 are associated with genotype, age, and sex DK Bhatt, A Basit, H Zhang, A Gaedigk, S Lee, KG Claw, A Mehrotra, ... Drug Metabolism and Disposition 46 (6), 888-896, 2018 | 55 | 2018 |
NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist, inhibits CGRP release in preclinical migraine models DK Bhatt, S Gupta, I Jansen-Olesen, JS Andrews, J Olesen Cephalalgia, 2012 | 53 | 2012 |
Genetic and nongenetic factors associated with protein abundance of flavin-containing monooxygenase 3 in human liver M Xu, DK Bhatt, CK Yeung, KG Claw, AS Chaudhry, A Gaedigk, ... Journal of Pharmacology and Experimental Therapeutics 363 (2), 265-274, 2017 | 52 | 2017 |
Ontogeny of hepatic sulfotransferases and prediction of age-dependent fractional contribution of sulfation in acetaminophen metabolism MK Ladumor, DK Bhatt, A Gaedigk, S Sharma, A Thakur, RE Pearce, ... Drug Metabolism and Disposition 47 (8), 818-831, 2019 | 50 | 2019 |
Novel interactions between gut microbiome and host drug-processing genes modify the hepatic metabolism of the environmental chemicals polybrominated diphenyl ethers CY Li, S Lee, S Cade, LJ Kuo, IR Schultz, DK Bhatt, B Prasad, ... Drug Metabolism and Disposition 45 (11), 1197-1214, 2017 | 44 | 2017 |
Quantitative characterization of UDP-glucuronosyltransferase 2B17 in human liver and intestine and its role in testosterone first-pass metabolism H Zhang, A Basit, D Busch, K Yabut, DK Bhatt, M Drozdzik, M Ostrowski, ... Biochemical pharmacology 156, 32-42, 2018 | 42 | 2018 |
The promises of quantitative proteomics in precision medicine B Prasad, M Vrana, A Mehrotra, K Johnson, DK Bhatt Journal of pharmaceutical sciences 106 (3), 738-744, 2017 | 40 | 2017 |
Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes C Nepal, B Zhu, CJ O’Rourke, DK Bhatt, D Lee, L Song, D Wang, ... Journal of hepatology 74 (5), 1132-1144, 2021 | 39 | 2021 |
Age-dependent protein abundance of cytosolic alcohol and aldehyde dehydrogenases in human liver DK Bhatt, A Gaedigk, RE Pearce, JS Leeder, B Prasad Drug Metabolism and Disposition 45 (9), 1044-1048, 2017 | 33 | 2017 |
Improvement of the closed cranial window model in rats by intracarotid infusion of signalling molecules implicated in migraine S Gupta, DK Bhatt, LJ Boni, J Olesen Cephalalgia, 2009 | 27 | 2009 |