Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia MLSB J. R. Rivas, Y. Liu, S. S. Alhakeem, J. M. Eckenrode, F. Marti, J. P ... Leukemia, 2021 | 45 | 2021 |
Base-promoted one-pot tandem reaction of 3-(1-alkynyl) chromones under microwave irradiation to functionalized amino-substituted xanthones Y Liu, L Huang, F Xie, Y Hu The Journal of Organic Chemistry 75 (18), 6304-6307, 2010 | 42 | 2010 |
Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis W Xing, J Ai, S Jin, Z Shi, X Peng, L Wang, Y Ji, D Lu, Y Liu, M Geng, Y Hu European journal of medicinal chemistry 95, 302-312, 2015 | 33 | 2015 |
Pyridazinone derivatives displaying highly potent and selective inhibitory activities against c-Met tyrosine kinase Y Liu, S Jin, X Peng, D Lu, L Zeng, Y Sun, J Ai, M Geng, Y Hu European Journal of Medicinal Chemistry 108, 322-333, 2016 | 27 | 2016 |
Methionine adenosyltransferase engineering to enable bioorthogonal platforms for AdoMet-utilizing enzymes TD Huber, JA Clinger, Y Liu, W Xu, MD Miller, GN Phillips Jr, JS Thorson ACS chemical biology 15 (3), 695-705, 2020 | 25 | 2020 |
Identification and synthesis of substituted pyrrolo [2, 3-d] pyrimidines as novel firefly luciferase inhibitors Y Liu, J Fang, H Cai, F Xiao, K Ding, Y Hu Bioorganic & medicinal chemistry 20 (18), 5473-5482, 2012 | 24 | 2012 |
Microwave Assisted Tandem Heck–Sonogashira Reactions of N,N-Di-Boc-Protected 6-Amino-5-iodo-2-methyl Pyrimidin-4-ol in An Efficient Approach to Functionalized Pyrido … Y Liu, S Jin, Z Wang, L Song, Y Hu Organic letters 16 (13), 3524-3527, 2014 | 19 | 2014 |
Y‐632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and … W Wang, Y Liu, Z Zhao, C Xie, Y Xu, Y Hu, H Quan, L Lou Cancer Science 107 (6), 782-790, 2016 | 18 | 2016 |
Phase Transfer Reagent Promoted Tandem Ring-Opening and Ring-Closing Reactions of Unique 3-(1-Alkynyl) Chromones Y Liu, S Jin, L Huang, Y Hu Organic letters 17 (9), 2134-2137, 2015 | 18 | 2015 |
Synthesis of novel functional polycyclic chromones through Michael addition and double cyclizations Y Liu, L Huang, F Xie, X Chen, Y Hu Organic & Biomolecular Chemistry 9 (8), 2680-2684, 2011 | 18 | 2011 |
Structure determination, functional characterization, and biosynthetic implications of nybomycin metabolites from a mining reclamation site-associated Streptomyces X Wang, SI Elshahawi, LV Ponomareva, Q Ye, Y Liu, GC Copley, ... Journal of natural products 82 (12), 3469-3476, 2019 | 17 | 2019 |
Total synthesis of griseusins and elucidation of the griseusin mechanism of action Y Zhang, Q Ye, LV Ponomareva, Y Cao, Y Liu, Z Cui, SG Van Lanen, ... Chemical Science 10 (32), 7641-7648, 2019 | 17 | 2019 |
Design and synthesis of novel benzo [d] oxazol-2 (3H)-one derivatives bearing 7-substituted-4-enthoxyquinoline moieties as c-Met kinase inhibitors D Lu, A Shen, Y Liu, X Peng, W Xing, J Ai, M Geng, Y Hu European journal of medicinal chemistry 115, 191-200, 2016 | 17 | 2016 |
A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-κB signaling and improves survival in mouse models of sepsis J Fang, Y Liu, J Li, W Liao, Y Hu, K Ding Acta Pharmacologica Sinica 33 (9), 1204-1216, 2012 | 12 | 2012 |
An organic molecule modulated chemoselective cyclization of alkynyl nitriles tethered to 2-alkyl substituted chromones with multireactive sites L Huang, Y Liu, F Xie, Y Hu Organic letters 14 (24), 6122-6125, 2012 | 11 | 2012 |
Mithramycin 2′-oximes with improved selectivity, pharmacokinetics, and Ewing sarcoma antitumor efficacy Y Liu, JM Eckenrode, Y Zhang, J Zhang, RC Hayden, A Kyomuhangi, ... Journal of medicinal chemistry 63 (22), 14067-14086, 2020 | 10 | 2020 |
Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia JR Rivas, SS Alhakeem, Y Liu, JM Eckenrode, F Marti, JP Collard, ... bioRxiv, 2020 | | 2020 |
a novel agent for treating hormone therapy resistant breast cancer TK Ratna K. Vadlamudi, G. R. S., Suryavathi Viswanadhapalli, ... AACR Annual Meeting 2016, 107th., 0 | | |