Structure- and function-based design of Plasmodium-selective proteasome inhibitors H Li, AJ O’Donoghue, WA Van Der Linden, SC Xie, E Yoo, IT Foe, L Tilley, ... Nature 530 (7589), 233-236, 2016 | 256 | 2016 |
Antibacterial activities of Groebke–Blackburn–Bienaymé-derived imidazo[1,2-a]pyridin-3-amines NM Shukla, DB Salunke, E Yoo, CA Mutz, R Balakrishna, SA David Bioorganic & medicinal chemistry 20 (19), 5850-5863, 2012 | 141 | 2012 |
Structure–Activity Relationships in Human Toll-like Receptor 8-Active 2,3-Diamino-furo[2,3-c]pyridines DB Salunke, E Yoo, NM Shukla, R Balakrishna, SS Malladi, KJ Serafin, ... Journal of medicinal chemistry 55 (18), 8137-8151, 2012 | 94 | 2012 |
Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure–activity relationship (QSAR) of diverse heterocyclic scaffolds E Yoo, DB Salunke, D Sil, X Guo, ACD Salyer, AR Hermanson, M Kumar, ... Journal of medicinal chemistry 57 (19), 7955-7970, 2014 | 84 | 2014 |
Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo [4, 5-c] quinolines HP Kokatla, E Yoo, DB Salunke, D Sil, CF Ng, R Balakrishna, SS Malladi, ... Organic & biomolecular chemistry 11 (7), 1179-1198, 2013 | 71 | 2013 |
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial … BH Stokes, E Yoo, JM Murithi, MR Luth, P Afanasyev, PCA da Fonseca, ... PLoS pathogens 15 (6), e1007722, 2019 | 66 | 2019 |
structure–activity relationship studies of functionally selective kappa opioid receptor agonists that modulate ERK 1/2 phosphorylation while preserving G protein over … KM Lovell, KJ Frankowski, EL Stahl, SR Slauson, E Yoo, TE Prisinzano, ... ACS chemical neuroscience 6 (8), 1411-1419, 2015 | 65 | 2015 |
Structure–activity relationships in human Toll-like receptor 2-specific monoacyl lipopeptides DB Salunke, NM Shukla, E Yoo, BM Crall, R Balakrishna, SS Malladi, ... Journal of medicinal chemistry 55 (7), 3353-3363, 2012 | 62 | 2012 |
Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors E Yoo, BH Stokes, H De Jong, M Vanaerschot, TRS Kumar, N Lawrence, ... Journal of the American Chemical Society 140 (36), 11424-11437, 2018 | 59 | 2018 |
The antimalarial natural product salinipostin A identifies essential α/β serine hydrolases involved in lipid metabolism in P. falciparum parasites E Yoo, CJ Schulze, BH Stokes, O Onguka, T Yeo, S Mok, NF Gnädig, ... Cell chemical biology 27 (2), 143-157. e5, 2020 | 56 | 2020 |
Structure–activity relationships in Toll-like receptor 7 agonistic 1 H-imidazo [4, 5-c] pyridines E Yoo, BM Crall, R Balakrishna, SS Malladi, LM Fox, AR Hermanson, ... Organic & biomolecular chemistry 11 (38), 6526-6545, 2013 | 55 | 2013 |
Preparation of piperazine derivatives as 5-HT7 receptor antagonists J Yoon, EA Yoo, JY Kim, AN Pae, H Rhim, WK Park, JY Kong, HYP Choo Bioorganic & medicinal chemistry 16 (10), 5405-5412, 2008 | 39 | 2008 |
Hyaluronic acid conjugates of TLR7/8 agonists for targeted delivery to secondary lymphoid tissue E Yoo, ACD Salyer, MJH Brush, Y Li, KL Trautman, NM Shukla, ... Bioconjugate chemistry 29 (8), 2741-2754, 2018 | 32 | 2018 |
Role of serine proteases at the tumor-stroma interface R Tagirasa, E Yoo Frontiers in immunology 13, 832418, 2022 | 26 | 2022 |
Design of Optical‐Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease‐Tissue Extracts M Tholen, JJ Yim, K Groborz, E Yoo, BA Martin, NS van den Berg, M Drag, ... Angewandte Chemie International Edition 59 (43), 19143-19152, 2020 | 21 | 2020 |
Covalent small molecule immunomodulators targeting the protease active site HR Kim, R Tagirasa, E Yoo Journal of Medicinal Chemistry 64 (9), 5291-5322, 2021 | 15 | 2021 |
Synthesis and biological evaluation of (phenylpiperazinyl-propyl) arylsulfonamides as selective 5-HT2A receptor antagonists E Yoo, J Yoon, AN Pae, H Rhim, WK Park, JY Kong, HYP Choo Bioorganic & medicinal chemistry 18 (4), 1665-1675, 2010 | 14 | 2010 |
Leveraging peptide substrate libraries to design inhibitors of bacterial lon protease BM Babin, P Kasperkiewicz, T Janiszewski, E Yoo, M Dra̧g, M Bogyo ACS chemical biology 14 (11), 2453-2462, 2019 | 12 | 2019 |
Antitubercular Activities of the Novel Synthesized 1, 2, 4‐Triazole Derivatives T Oh, F Hayat, E Yoo, SN Cho, YY Sheen, DK Kim, HY Park Choo Bulletin of the Korean Chemical Society 36 (1), 43-51, 2015 | 12 | 2015 |
Covalent inhibition by a natural product-inspired latent electrophile DP Byun, J Ritchie, Y Jung, R Holewinski, HR Kim, R Tagirasa, J Ivanic, ... Journal of the American Chemical Society 145 (20), 11097-11109, 2023 | 11 | 2023 |