Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models S Vicent, R Chen, LC Sayles, C Lin, RG Walker, AK Gillespie, ... The Journal of clinical investigation 120 (11), 3940-3952, 2010 | 164 | 2010 |
A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma R Chen, P Khatri, PK Mazur, M Polin, Y Zheng, D Vaka, CD Hoang, ... Cancer research 74 (10), 2892-2902, 2014 | 163 | 2014 |
Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for Clcf1 and Il-6 in non–small cell lung cancer in vivo S Vicent, LC Sayles, D Vaka, P Khatri, O Gevaert, R Chen, Y Zheng, ... Cancer research 72 (22), 5744-5756, 2012 | 136 | 2012 |
Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis MM Howarth, D Simpson, SP Ngok, B Nieves, R Chen, Z Siprashvili, ... The Journal of clinical investigation 124 (12), 5275-5290, 2014 | 96 | 2014 |
Multimodality imaging of gene transfer with a receptor-based reporter gene R Chen, JJ Parry, WJ Akers, MY Berezin, IM El Naqa, S Achilefu, ... Journal of Nuclear Medicine 51 (9), 1456-1463, 2010 | 23 | 2010 |
ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses AM Herzner, Z Khan, EL Van Nostrand, S Chan, T Cuellar, R Chen, ... Journal of Experimental Medicine 218 (9), e20201833, 2021 | 22 | 2021 |
Two Is Better Than One: Combining IGF1R and MEK Blockade as a Promising Novel Treatment Strategy Against KRAS-Mutant Lung Cancer R Chen, EA Sweet-Cordero Cancer discovery 3 (5), 491-493, 2013 | 17 | 2013 |
Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2 JJ Parry, R Chen, R Andrews, KA Lears, BE Rogers Endocrinology 153 (6), 2747-2755, 2012 | 14 | 2012 |
A novel loss-of-function screen identifies Wt1 as a key regulator of lung cancer driven by oncogenic K-ras S Vicent, R Chen, LC Sayles, C Lin, RG Walker, AK Gillespie, DE Root, ... JOURNAL OF THORACIC ONCOLOGY 5 (6), S230-S231, 2010 | 1 | 2010 |
Identifying KRAS synthetic lethal interactions using systems biology and functional genomics R Chen, D Gwinn, A Sweet-Cordero MOLECULAR CANCER RESEARCH 12, 2014 | | 2014 |
Abstract IA16: Identifying KRAS synthetic lethal interactions using systems biology and functional genomics R Chen, D Gwinn, A Sweet-Cordero Molecular Cancer Therapeutics 12 (12_Supplement), IA16-IA16, 2014 | | 2014 |
Abstract A31: The long noncoding RNA lnc277 mediates a repressive gene signature in Ewing's sarcoma M Marques, D Simpson, R Chen, D Vaka, M Breese, A Brunner, R West, ... Cancer Research 74 (20_Supplement), A31-A31, 2014 | | 2014 |
Abstract PR08: Identifying effectors of WT1 that regulate KRAS-induced senescence and chemoresistance in non-small cell lung cancer R Chen, DR Simpson, Y Zheng, D Vaka, S Vicent, A Sweet-Cordero Molecular Cancer Therapeutics 12 (5_Supplement), PR08-PR08, 2013 | | 2013 |
Blockade as a Promising Novel Treatment Strategy Against KRAS-Mutant Lung Cancer R Chen, EA Sweet-Cordero | | 2013 |
Signal rewiring induced by EWS/FLI-1 in mouse and human mesenchymal stem cells M Marques, B Nieves, R Chen, D Vaka, C Chan, G Zheng, H Chang, ... Cancer Research 72 (8_Supplement), 1427-1427, 2012 | | 2012 |
Abstract A41: SOX11 transcriptionally regulates a cytokine-based gene signature in lung cancer-associated fibroblasts (LCAF) to promote tumor growth S Vicent, AK Gillespie, D Vakaa, P Khatri, R Chen, O Gevaert, N Clarke, ... Clinical Cancer Research 18 (3_Supplement), A41-A41, 2012 | | 2012 |
Pawel Mazur PK Mazur, N Reynoird, P Khatri, PW Jansen, AW Wilkinson, S Liu, ... | | |