Palmitoylation-dependent activation of MC1R prevents melanomagenesis S Chen, B Zhu, C Yin, W Liu, C Han, B Chen, T Liu, X Li, X Chen, C Li, ... Nature 549 (7672), 399-403, 2017 | 183 | 2017 |
Germline MC1R status influences somatic mutation burden in melanoma CD Robles-Espinoza, ND Roberts, S Chen, FP Leacy, LB Alexandrov, ... Nature communications 7 (1), 12064, 2016 | 146 | 2016 |
Uniform nanosecond pulsed dielectric barrier discharge plasma enhances anti‐tumor effects by induction of immunogenic cell death in tumors and stimulation of macrophages A Lin, B Truong, A Pappas, L Kirifides, A Oubarri, S Chen, S Lin, ... Plasma processes and polymers 12 (12), 1392-1399, 2015 | 141 | 2015 |
Hypoxia‐inducible factor‐1: a critical player in the survival strategy of stressed cells S Chen, N Sang Journal of cellular biochemistry 117 (2), 267-278, 2016 | 123 | 2016 |
AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol S Chen, C Yin, T Lao, D Liang, D He, C Wang, N Sang Cell Cycle 14 (15), 2520-2536, 2015 | 103 | 2015 |
Histone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia‐inducible factors S Chen, N Sang BioMed Research International 2011 (1), 197946, 2011 | 103 | 2011 |
Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells M Meng, S Chen, T Lao, D Liang, N Sang Cell cycle 9 (19), 3921-3932, 2010 | 97 | 2010 |
Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy B Zhu, L Tang, S Chen, C Yin, S Peng, X Li, T Liu, W Liu, C Han, ... Oncogene 37 (36), 4941-4954, 2018 | 92 | 2018 |
The protective role of DOT1L in UV-induced melanomagenesis B Zhu, S Chen, H Wang, C Yin, C Han, C Peng, Z Liu, L Wan, X Zhang, ... Nature communications 9 (1), 259, 2018 | 83 | 2018 |
Pharmacological targeting of STK19 inhibits oncogenic NRAS-driven melanomagenesis C Yin, B Zhu, T Zhang, T Liu, S Chen, Y Liu, X Li, X Miao, S Li, X Mi, ... Cell 176 (5), 1113-1127. e16, 2019 | 82 | 2019 |
Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads S Chen, C Han, X Miao, X Li, C Yin, J Zou, M Liu, S Li, L Stawski, B Zhu, ... Nature communications 10 (1), 877, 2019 | 72 | 2019 |
IL-6/STAT3 axis dictates the PNPLA3-mediated susceptibility to non-alcoholic fatty liver disease J Park, Y Zhao, F Zhang, S Zhang, AC Kwong, Y Zhang, HH Hoffmann, ... Journal of Hepatology 78 (1), 45-56, 2023 | 55 | 2023 |
Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate C Yin, D He, S Chen, X Tan, N Sang Oncotarget 7 (30), 47494, 2016 | 26 | 2016 |
Two mutations impair the stability and function of ubiquitin‐activating enzyme (E1) T Lao, S Chen, N Sang Journal of cellular physiology 227 (4), 1561-1568, 2012 | 15 | 2012 |
AMPK phosphorylates ZDHHC13 to increase MC1R activity and suppress melanomagenesis Y Sun, X Li, C Yin, J Zhang, E Liang, X Wu, Y Ni, J Arbesman, CR Goding, ... Cancer Research 83 (7), 1062-1073, 2023 | 9 | 2023 |
An activity-integrated strategy of the identification, screening and determination of potential neuraminidase inhibitors from Radix Scutellariae W Liu, H Wang, B Zhu, C Yin, S Chen, J Li, X Yu, JT Azietaku, M An, ... Plos one 12 (5), e0175751, 2017 | 9 | 2017 |
MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression VS Chelakkot, K Thomas, T Romigh, A Fong, L Li, S Ronen, S Chen, ... NPJ Precision Oncology 7 (1), 85, 2023 | 7 | 2023 |
A novel TGF-β signaling pathway promotes a slow growing phenotype of cancer cells in response to glutamine insufficiency D He, C Yin, S Qie, S Chen, N Sang Cancer Research 77 (13_Supplement), 3562-3562, 2017 | | 2017 |
Exogenous pyruvate supports oxygen-independent tumor cell proliferation by serving as an oxygen surrogate to maintain homeostasis of NAD+/NADH C Yin, D He, S Chen, N Sang Cancer Research 76 (14_Supplement), 2802-2802, 2016 | | 2016 |
Abstract LB-124: Histone deacetylase 5 stabilizes HIF-1α through Hsp70 deacetylation in cytosol S Chen, C Yin, T Lao, D Liang, N Sang Cancer Research 74 (19_Supplement), LB-124-LB-124, 2014 | | 2014 |