The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation A Plotnikov, E Zehorai, S Procaccia, R Seger Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (9), 1619-1633, 2011 | 1199 | 2011 |
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity GS Kinker, AC Greenwald, R Tal, Z Orlova, MS Cuoco, JM McFarland, ... Nature genetics 52 (11), 1208-1218, 2020 | 287 | 2020 |
Rapid covalent-probe discovery by electrophile-fragment screening E Resnick, A Bradley, J Gan, A Douangamath, T Krojer, R Sethi, ... Journal of the American Chemical Society 141 (22), 8951-8968, 2019 | 260 | 2019 |
The subcellular localization of MEK and ERK—a novel nuclear translocation signal (NTS) paves a way to the nucleus E Zehorai, Z Yao, A Plotnikov, R Seger Molecular and cellular endocrinology 314 (2), 213-220, 2010 | 162 | 2010 |
The nuclear translocation of ERK1/2 as an anticancer target A Plotnikov, K Flores, G Maik-Rachline, E Zehorai, E Kapri-Pardes, ... Nature communications 6 (1), 6685, 2015 | 137 | 2015 |
Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway B Varghese, H Barriere, CJ Carbone, A Banerjee, G Swaminathan, ... Molecular and cellular biology 28 (17), 5275-5287, 2008 | 109 | 2008 |
Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells I Michailovici, HA Harrington, HH Azogui, Y Yahalom-Ronen, A Plotnikov, ... Development 141 (13), 2611-2620, 2014 | 106 | 2014 |
Impaired turnover of prolactin receptor contributes to transformation of human breast cells. FSY 9. Plotnikov A, Varghese B, Tran TH, Liu C, Rui H Cancer Research 69 (3), 3165-72, 2009 | 65 | 2009 |
Ligand-independent pathway that controls stability of interferon alpha receptor J Liu, A Plotnikov, A Banerjee, KGS Kumar, J Ragimbeau, Z Marijanovic, ... Biochemical and biophysical research communications 367 (2), 388-393, 2008 | 64 | 2008 |
RAPID COMMUNICATION: Prolactin stimulates ubiquitination, initial internalization, and degradation of its receptor via catalytic activation of Janus kinase 2 G Swaminathan, B Varghese, C Thangavel, CJ Carbone, A Plotnikov, ... Journal of Endocrinology 196 (2), R1, 2008 | 61 | 2008 |
Oncogene-mediated inhibition of glycogen synthase kinase 3β impairs degradation of prolactin receptor A Plotnikov, Y Li, TH Tran, W Tang, JP Palazzo, H Rui, SY Fuchs Cancer research 68 (5), 1354-1361, 2008 | 60 | 2008 |
Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade YD Shaul, G Gibor, A Plotnikov, R Seger Genes & development 23 (15), 1779-1790, 2009 | 59 | 2009 |
Tumor growth retardation, cure, and induction of antitumor immunity in B16 melanoma-bearing mice by low electric field-enhanced chemotherapy I Entin, A Plotnikov, R Korenstein, Y Keisari Clinical cancer research 9 (8), 3190-3197, 2003 | 58 | 2003 |
Tunable methacrylamides for covalent ligand directed release chemistry RN Reddi, E Resnick, A Rogel, BV Rao, R Gabizon, K Goldenberg, ... Journal of the American Chemical Society 143 (13), 4979-4992, 2021 | 53 | 2021 |
Nuclear ERK translocation is mediated by protein kinase CK2 and accelerated by autophosphorylation A Plotnikov, D Chuderland, Y Karamansha, O Livnah, R Seger Cell. Physiol. Biochem 53 (2), 366-387, 2019 | 39 | 2019 |
The role of ERK signaling in experimental autoimmune encephalomyelitis K Birkner, B Wasser, J Loos, A Plotnikov, R Seger, F Zipp, E Witsch, ... International journal of molecular sciences 18 (9), 1990, 2017 | 33 | 2017 |
Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferation B Varghese, G Swaminathan, A Plotnikov, C Tzimas, N Yang, H Rui, ... Molecular endocrinology 24 (12), 2356-2365, 2010 | 32 | 2010 |
Low electric field enhanced chemotherapy can cure mice with CT-26 colon carcinoma and induce anti-tumour immunity A Plotnikov, D Fishman, T Tichler, R Korenstein, Y Keisari Clinical & Experimental Immunology 138 (3), 410-416, 2004 | 29 | 2004 |
High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria T Yardeni, R Fine, Y Joshi, T Gradus-Pery, N Kozer, I Reichenstein, ... Scientific reports 8 (1), 59, 2018 | 28 | 2018 |
A novel allosteric mechanism of NF-κB dimerization and DNA binding targeted by an anti-inflammatory drug S Ashkenazi, A Plotnikov, A Bahat, E Ben-Zeev, S Warszawski, R Dikstein Molecular and Cellular Biology 36 (8), 1237-1247, 2016 | 24 | 2016 |