关注
Antons Martincuks
Antons Martincuks
City of Hope Comprehensive Cancer Center
在 coh.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
STAT proteins in cancer: orchestration of metabolism
YJ Li, C Zhang, A Martincuks, A Herrmann, H Yu
Nature reviews Cancer 23 (3), 115-134, 2023
1202023
CD44 in ovarian cancer progression and therapy resistance—a critical role for STAT3
A Martincuks, PC Li, Q Zhao, C Zhang, YJ Li, H Yu, ...
Frontiers in oncology 10, 589601, 2020
582020
Soluble heparan sulfate in serum of septic shock patients induces mitochondrial dysfunction in murine cardiomyocytes
L Martin, C Peters, S Schmitz, J Moellmann, A Martincuks, N Heussen, ...
Shock 44 (6), 569-577, 2015
512015
STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer
L Ding, Q Wang, A Martincuks, MJ Kearns, T Jiang, Z Lin, X Cheng, ...
Journal for immunotherapy of cancer 11 (1), 2023
472023
Nuclear translocation of STAT3 and NF-κB are independent of each other but NF-κB supports expression and activation of STAT3
A Martincuks, K Andryka, A Küster, H Schmitz-Van de Leur, ...
Cellular signalling 32, 36-47, 2017
432017
Consequences of the disease-related L78R mutation for dimerization and activity of STAT3
T Domoszlai, A Martincuks, D Fahrenkamp, H Schmitz-Van de Leur, ...
Journal of cell science 127 (9), 1899-1910, 2014
382014
Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive …
A Schumacher, B Denecke, T Braunschweig, J Stahlschmidt, S Ziegler, ...
Journal of Hematology & Oncology 8, 1-16, 2015
272015
PARP inhibition activates STAT3 in both tumor and immune cells underlying therapy resistance and immunosuppression in ovarian cancer
A Martincuks, J Song, A Kohut, C Zhang, YJ Li, Q Zhao, E Mak, ...
Frontiers in Oncology 11, 724104, 2021
212021
Dissecting functions of the N-terminal domain and GAS-site recognition in STAT3 nuclear trafficking
A Martincuks, D Fahrenkamp, S Haan, A Herrmann, A Küster, ...
Cellular signalling 28 (8), 810-825, 2016
172016
Phase I trial of daily subcutaneous SPL-108 injections in combination with paclitaxel in patients with platinum resistant CD44+ advanced ovarian epithelial cancer
E Girda, J Hou, D Nelson, M Finlayson, AB De Meritens, M Chekmareiva, ...
International Journal of Gynecologic Cancer 32 (8), 2022
122022
The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum
L Martin, C Peters, L Heinbockel, J Moellmann, A Martincuks, ...
Innate Immunity 22 (8), 612-619, 2016
112016
Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning
E Zechendorf, P Vaßen, J Zhang, A Hallawa, A Martincuks, O Krenkel, ...
Frontiers in Immunology 9, 393, 2018
82018
Targeting PARG induces tumor cell growth inhibition and antitumor immune response by reducing phosphorylated STAT3 in ovarian cancer
A Martincuks, C Zhang, T Austria, YJ Li, R Huang, NL Santiago, A Kohut, ...
Journal for Immunotherapy of Cancer 12 (4), 2024
62024
Niraparib-induced STAT3 inhibition increases its antitumor effects
Q Zhao, A Kohut, YJ Li, A Martincuks, T Austria, C Zhang, NL Santiago, ...
Frontiers in Oncology 12, 966492, 2022
52022
T-cell redirecting therapies in haematological malignancies: current developments and novel strategies for improved targeting
GSF Anderson, MA Chapman
Molecular Therapy, 2024
3*2024
Local CpG-Stat3 siRNA treatment improves antitumor effects of immune checkpoint inhibitors
C Zhang, R Huang, L Ren, JE Song, M Kortylewski, P Swiderski, ...
bioRxiv, 2023
12023
STAT3 is a potential therapeutic target in cervical cancer (257)
A Kohut, A Martincuks, NL Santiago, T Austria, Q Zhao, S Lee, A Tergas, ...
Gynecologic Oncology 166, S137-S138, 2022
12022
A platform to deliver single and bi-specific Cas9/guide RNA to perturb genes in vitro and in vivo
YJ Li, SH Chien, R Huang, A Herrmann, Q Zhao, PC Li, C Zhang, ...
Molecular Therapy 32 (10), 3629-3649, 2024
2024
EP017/# 738 Insights from ovarian cancer patients’ rapid autopsy shed light on mechanisms of CD4+ T cell-mediated pre-metastatic niche formation through the STAT3 axis
A Martincuks, R Senguttuvan, M Kujawski, S Priceman, E Barragan, K Ihle, ...
International Journal of Gynecologic Cancer 33 (Suppl 4), 2023
2023
EP245/# 993 Niraparib induces ovarian cancer cell apoptosis regardless of homologous recombination status through downregulation of the oncogenic SRC/STAT3 axis
A Kohut, Q Zhao, YJ Li, A Martincuks, T Austria, C Zhang, N Lugo, ...
International Journal of Gynecologic Cancer 32 (Suppl 3), 2022
2022
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