STAT proteins in cancer: orchestration of metabolism YJ Li, C Zhang, A Martincuks, A Herrmann, H Yu Nature reviews Cancer 23 (3), 115-134, 2023 | 120 | 2023 |
CD44 in ovarian cancer progression and therapy resistance—a critical role for STAT3 A Martincuks, PC Li, Q Zhao, C Zhang, YJ Li, H Yu, ... Frontiers in oncology 10, 589601, 2020 | 58 | 2020 |
Soluble heparan sulfate in serum of septic shock patients induces mitochondrial dysfunction in murine cardiomyocytes L Martin, C Peters, S Schmitz, J Moellmann, A Martincuks, N Heussen, ... Shock 44 (6), 569-577, 2015 | 51 | 2015 |
STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer L Ding, Q Wang, A Martincuks, MJ Kearns, T Jiang, Z Lin, X Cheng, ... Journal for immunotherapy of cancer 11 (1), 2023 | 47 | 2023 |
Nuclear translocation of STAT3 and NF-κB are independent of each other but NF-κB supports expression and activation of STAT3 A Martincuks, K Andryka, A Küster, H Schmitz-Van de Leur, ... Cellular signalling 32, 36-47, 2017 | 43 | 2017 |
Consequences of the disease-related L78R mutation for dimerization and activity of STAT3 T Domoszlai, A Martincuks, D Fahrenkamp, H Schmitz-Van de Leur, ... Journal of cell science 127 (9), 1899-1910, 2014 | 38 | 2014 |
Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive … A Schumacher, B Denecke, T Braunschweig, J Stahlschmidt, S Ziegler, ... Journal of Hematology & Oncology 8, 1-16, 2015 | 27 | 2015 |
PARP inhibition activates STAT3 in both tumor and immune cells underlying therapy resistance and immunosuppression in ovarian cancer A Martincuks, J Song, A Kohut, C Zhang, YJ Li, Q Zhao, E Mak, ... Frontiers in Oncology 11, 724104, 2021 | 21 | 2021 |
Dissecting functions of the N-terminal domain and GAS-site recognition in STAT3 nuclear trafficking A Martincuks, D Fahrenkamp, S Haan, A Herrmann, A Küster, ... Cellular signalling 28 (8), 810-825, 2016 | 17 | 2016 |
Phase I trial of daily subcutaneous SPL-108 injections in combination with paclitaxel in patients with platinum resistant CD44+ advanced ovarian epithelial cancer E Girda, J Hou, D Nelson, M Finlayson, AB De Meritens, M Chekmareiva, ... International Journal of Gynecologic Cancer 32 (8), 2022 | 12 | 2022 |
The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum L Martin, C Peters, L Heinbockel, J Moellmann, A Martincuks, ... Innate Immunity 22 (8), 612-619, 2016 | 11 | 2016 |
Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning E Zechendorf, P Vaßen, J Zhang, A Hallawa, A Martincuks, O Krenkel, ... Frontiers in Immunology 9, 393, 2018 | 8 | 2018 |
Targeting PARG induces tumor cell growth inhibition and antitumor immune response by reducing phosphorylated STAT3 in ovarian cancer A Martincuks, C Zhang, T Austria, YJ Li, R Huang, NL Santiago, A Kohut, ... Journal for Immunotherapy of Cancer 12 (4), 2024 | 6 | 2024 |
Niraparib-induced STAT3 inhibition increases its antitumor effects Q Zhao, A Kohut, YJ Li, A Martincuks, T Austria, C Zhang, NL Santiago, ... Frontiers in Oncology 12, 966492, 2022 | 5 | 2022 |
T-cell redirecting therapies in haematological malignancies: current developments and novel strategies for improved targeting GSF Anderson, MA Chapman Molecular Therapy, 2024 | 3* | 2024 |
Local CpG-Stat3 siRNA treatment improves antitumor effects of immune checkpoint inhibitors C Zhang, R Huang, L Ren, JE Song, M Kortylewski, P Swiderski, ... bioRxiv, 2023 | 1 | 2023 |
STAT3 is a potential therapeutic target in cervical cancer (257) A Kohut, A Martincuks, NL Santiago, T Austria, Q Zhao, S Lee, A Tergas, ... Gynecologic Oncology 166, S137-S138, 2022 | 1 | 2022 |
A platform to deliver single and bi-specific Cas9/guide RNA to perturb genes in vitro and in vivo YJ Li, SH Chien, R Huang, A Herrmann, Q Zhao, PC Li, C Zhang, ... Molecular Therapy 32 (10), 3629-3649, 2024 | | 2024 |
EP017/# 738 Insights from ovarian cancer patients’ rapid autopsy shed light on mechanisms of CD4+ T cell-mediated pre-metastatic niche formation through the STAT3 axis A Martincuks, R Senguttuvan, M Kujawski, S Priceman, E Barragan, K Ihle, ... International Journal of Gynecologic Cancer 33 (Suppl 4), 2023 | | 2023 |
EP245/# 993 Niraparib induces ovarian cancer cell apoptosis regardless of homologous recombination status through downregulation of the oncogenic SRC/STAT3 axis A Kohut, Q Zhao, YJ Li, A Martincuks, T Austria, C Zhang, N Lugo, ... International Journal of Gynecologic Cancer 32 (Suppl 3), 2022 | | 2022 |