Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect S Sana, VG Reddy, S Bhandari, TS Reddy, R Tokala, AP Sakla, ... European Journal of Medicinal Chemistry 200, 112457, 2020 | 65 | 2020 |
Synthesis of 1, 2, 4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents R Tokala, S Bale, IP Janrao, A Vennela, NP Kumar, KR Senwar, ... Bioorganic & medicinal chemistry letters 28 (10), 1919-1924, 2018 | 59 | 2018 |
Targeting DNA Minor Groove by Hybrid Molecules as Anticancer Agents S Nekkanti, R Tokala, N Shankaraiah Current medicinal chemistry 24 (26), 2887-2907, 2017 | 57 | 2017 |
Design and Synthesis of DNA‐Interactive β‐Carboline–Oxindole Hybrids as Cytotoxic and Apoptosis‐Inducing Agents R Tokala, S Thatikonda, US Vanteddu, S Sana, C Godugu, ... ChemMedChem 13 (18), 1909-1922, 2018 | 51 | 2018 |
Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: Synthesis, in silico and cell growth inhibition studies S Sana, VG Reddy, TS Reddy, R Tokala, R Kumar, SK Bhargava, ... Bioorganic Chemistry 110, 104765, 2021 | 49 | 2021 |
Synthesis and in vitro cytotoxicity evaluation of β-carboline-linked 2, 4-thiazolidinedione hybrids: potential DNA intercalation and apoptosis-inducing studies R Tokala, S Thatikonda, S Sana, P Regur, C Godugu, N Shankaraiah New Journal of Chemistry 42 (19), 16226-16236, 2018 | 49 | 2018 |
Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors S Sana, R Tokala, DM Bajaj, N Nagesh, KK Bokara, G Kiranmai, ... Bioorganic chemistry 93, 103317, 2019 | 43 | 2019 |
Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies NP Kumar, S Thatikonda, R Tokala, SS Kumari, UJ Lakshmi, C Godugu, ... Bioorganic & medicinal chemistry 26 (8), 1996-2008, 2018 | 40 | 2018 |
Design and synthesis of DNA-intercalative naphthalimide-benzothiazole/cinnamide derivatives: Cytotoxicity evaluation and topoisomerase-IIα inhibition NS Rao, N Nagesh, VL Nayak, S Sunkari, R Tokala, G Kiranmayi, ... MedChemCommun, 10 (2019), 72 –79, 0 | 37* | |
Synthesis of Combretastatin‐A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and … C Jadala, M Sathish, P Anchi, R Tokala, UJ Lakshmi, VG Reddy, ... ChemMedChem 14 (24), 2052-2060, 2019 | 36 | 2019 |
Synthesis and in vitro cytotoxicity evaluation of β-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition C Jadala, M Sathish, TS Reddy, VG Reddy, R Tokala, SK Bhargava, ... Bioorganic & medicinal chemistry 27 (15), 3285-3298, 2019 | 36 | 2019 |
Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity R Tokala, S Sana, UJ Lakshmi, P Sankarana, DK Sigalapalli, N Gadewal, ... Bioorganic chemistry 105, 104357, 2020 | 34 | 2020 |
Ru (II)-Catalyzed Regioselective Hydroxymethylation of β-Carbolines and Isoquinolines via C–H Functionalization: Probing the Mechanism by Online ESI-MS/MS Screening R Tokala, D Bora, S Sana, FM Nachtigall, LS Santos, N Shankaraiah The Journal of organic chemistry 84 (9), 5504-5513, 2019 | 34 | 2019 |
Reliability of click chemistry on drug discovery: a personal account N Shankaraiah, AP Sakla, K Laxmikeshav, R Tokala The Chemical Record 20 (4), 253-272, 2020 | 33 | 2020 |
Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction R Tokala, S Mahajan, G Kiranmai, DK Sigalapalli, S Sana, SE John, ... Bioorganic Chemistry 106, 104481, 2021 | 32 | 2021 |
Synthesis of 1, 2, 3‐Triazolo‐fused‐tetrahydro‐β‐carboline Derivatives via 1, 3‐Dipolar Cycloaddition Reaction: Cytotoxicity Evaluation and DNA‐Binding studies S Nekkanti, V Pooladanda, M Veldandi, R Tokala, C Godugu, ... ChemistrySelect 2 (24), 7210-7221, 2017 | 31 | 2017 |
Synthesis of DNA interactive C3-trans-cinnamide linked β-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors M Sathish, SC Dushantrao, S Nekkanti, R Tokala, S Thatikonda, ... Bioorganic & medicinal chemistry 26 (17), 4916-4929, 2018 | 27 | 2018 |
A recyclable and water soluble copper (I)-catalyst: one-pot synthesis of 1, 4-disubstituted 1, 2, 3-triazoles and their biological evaluation S Nekkanti, K Veeramani, SS Kumari, R Tokala, N Shankaraiah RSC Advances 6 (105), 103556-103566, 2016 | 27 | 2016 |
Synthesis of New 1, 2, 3-Triazolo-naphthalimide/phthalimide Conjugates via ‘Click'Reaction: DNA Intercalation and Cytotoxic Studies N Shankaraiah, NP Kumar, R Tokala, BS Gayatri, V Talla, LS Santos Journal of the Brazilian Chemical Society 30, 454-461, 2019 | 25 | 2019 |
Contribution of Knoevenagel Condensation Products towards Development of Anticancer Agents: An Updated Review N Shankaraiah, R Tokala, D Bora ChemMedChem, 2022 | 22 | 2022 |