Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing RT Davis, K Blake, D Ma, MBI Gabra, GA Hernandez, AT Phung, Y Yang, ... Nature cell biology 22 (3), 310-320, 2020 | 237 | 2020 |
Collagen density modulates triple-negative breast cancer cell metabolism through adhesion-mediated contractility EJ Mah, AEYT Lefebvre, GE McGahey, AF Yee, MA Digman Scientific reports 8 (1), 17094, 2018 | 71 | 2018 |
Automated segmentation and tracking of mitochondria in live-cell time-lapse images AEYT Lefebvre, D Ma, K Kessenbrock, DA Lawson, MA Digman Nature Methods 18 (9), 1091-1102, 2021 | 70 | 2021 |
LKB1 promotes metabolic flexibility in response to energy stress SJ Parker, RU Svensson, AS Divakaruni, AE Lefebvre, AN Murphy, ... Metabolic engineering 43, 208-217, 2017 | 57 | 2017 |
Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer SK Chun, BM Fortin, RC Fellows, AN Habowski, A Verlande, WA Song, ... Science advances 8 (31), eabo2389, 2022 | 47 | 2022 |
Microenvironmental stiffness induces metabolic reprogramming in glioblastoma A Sohrabi, AEYT Lefebvre, MJ Harrison, MC Condro, TM Sanazzaro, ... Cell reports 42 (10), 2023 | 9 | 2023 |
The actin binding protein profilin 1 is critical for mitochondria function TA Read, BA Cisterna, K Skruber, S Ahmadieh, HL Lindamood, JA Vitriol, ... BioRxiv, 2023 | 9 | 2023 |
Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis D Ma, GA Hernandez, AEYT Lefebvre, H Alshetaiwi, K Blake, KR Dave, ... Communications biology 4 (1), 1268, 2021 | 8 | 2021 |
The microenvironment dictates glycocalyx construction and immune surveillance KM Tharp, S Park, GA Timblin, AL Richards, JA Berg, NM Twells, ... Research Square, 2023 | 2 | 2023 |
The actin binding protein profilin 1 localizes inside mitochondria and is critical for their function TA Read, BA Cisterna, K Skruber, S Ahmadieh, TM Liu, JA Vitriol, Y Shi, ... EMBO reports 25 (8), 3240-3262, 2024 | 1 | 2024 |
Morphological and genetic screens reveal mechanisms of BiDAC-induced plasma membrane protein degradation K Bersuker, Q Jafri, J Lazzari-Dean, M Sangha, S Villa, A Lefebvre, ... | | 2024 |
Nellie: Automated organelle segmentation, tracking, and hierarchical feature extraction in 2D/3D live-cell microscopy AEYT Lefebvre, G Sturm, TY Lin, E Stoops, MP Lopez, ... arXiv preprint arXiv:2403.13214, 2024 | | 2024 |
Metabolic profiling and tracking phenotypic changes in mitochondria in cancer cells with mitometer and the phasor approach to FLIM MA Digman, G Tedeschi, L Scipioni, AE Lefebvre, F Palomba Biophysical Journal 123 (3), 36a, 2024 | | 2024 |
BIOMIMETIC HYALURONIC ACID-BASED HYDROGELS TO INVESTIGATE ROLE OF TUMOR BIOPHYSICAL PROPERTIES ON GLIOBLASTOMA (GBM) PROGRESSION A Sohrabi, J Liang, A Lefebvre, M Condro, H Kornblum, M Digman, ... TISSUE ENGINEERING PART A 28, S517-S517, 2022 | | 2022 |
Effects Of Matrix Stiffness On Glioblastoma Metabolism SK Seidlits, A Sohrabi, A Lefebvre, M Condro, HI Kornblum, MA Digman | | 2022 |
TRACKING MITOCHONDRIA REVEALS METABOLIC AND DYNAMIC HETEROGENEITY IN BREAST CANCERS AEYT Lefebvre 2021 Annual Meeting, 2021 | | 2021 |
Tracking Motility and Morphology of Individual Mitochondria Reveals Large Heterogeneities in Breast Cancer Subtypes AEYT Lefebvre, D Ma, K Kessenbrock, DA Lawson, MA Digman Biophysical Journal 120 (3), 194a, 2021 | | 2021 |
The Phenotypic Investigation of Mitochondria in Cancer A Lefebvre University of California, Irvine, 2021 | | 2021 |
Non-destructively Analyzing the Metabolic Dysregulation of Invasive Cancer Cells on an Intracellular Scale AEYT Lefebvre, FA Adame, M Liu, MA Digman Biophysical Journal 118 (3), 307a, 2020 | | 2020 |
The Phasor FLIM Analysis Monitors Metabolic Changes at the Leading Edge in Response to Rac Photo-Activation and Mitochondrial Transport in MDA MB231 Cells MA Digman, A Lefebvre, F Adame, E Fong Biophysical Journal 116 (3), 442a, 2019 | | 2019 |