Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding S Ouyang, X Song, Y Wang, H Ru, N Shaw, Y Jiang, F Niu, Y Zhu, W Qiu, ... Immunity 36 (6), 1073-1086, 2012 | 384 | 2012 |
Molecular mechanism of V (D) J recombination from synaptic RAG1-RAG2 complex structures H Ru, MG Chambers, TM Fu, AB Tong, M Liao, H Wu Cell 163 (5), 1138-1152, 2015 | 190 | 2015 |
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage L Zhao, T Hua, C Crowley, H Ru, X Ni, N Shaw, L Jiao, W Ding, L Qu, ... Cell research 24 (3), 344-358, 2014 | 123 | 2014 |
Characterization of T and B cell repertoire diversity in patients with RAG deficiency YN Lee, F Frugoni, K Dobbs, I Tirosh, L Du, FA Ververs, H Ru, ... Science immunology 1 (6), eaah6109, 2016 | 98 | 2016 |
Crystal structure of the WD40 domain dimer of LRRK2 P Zhang, Y Fan, H Ru, L Wang, VG Magupalli, SS Taylor, DR Alessi, ... Proceedings of the National Academy of Sciences 116 (5), 1579-1584, 2019 | 73 | 2019 |
New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16 X Ni, H Ru, F Ma, L Zhao, N Shaw, Y Feng, W Ding, W Gong, Q Wang, ... Journal of molecular cell biology 8 (1), 51-61, 2016 | 55 | 2016 |
DNA melting initiates the RAG catalytic pathway H Ru, W Mi, P Zhang, FW Alt, DG Schatz, M Liao, H Wu Nature Structural and Molecular Biology 25 (8), 732-742, 2018 | 50 | 2018 |
Structural basis for termination of AIM2-mediated signaling by p202 H Ru, X Ni, L Zhao, C Crowley, W Ding, LW Hung, N Shaw, G Cheng, ... Cell research 23 (6), 855-858, 2013 | 48 | 2013 |
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity Z Qin, X Fang, W Sun, Z Ma, T Dai, S Wang, Z Zong, H Huang, H Ru, H Lu, ... Nature immunology 23 (8), 1193-1207, 2022 | 37 | 2022 |
Structural biology study of human TNF receptor associated factor 4 TRAF domain F Niu, H Ru, W Ding, S Ouyang, ZJ Liu Protein & cell 4 (9), 687-694, 2013 | 27 | 2013 |
S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS H Ru, L Zhao, W Ding, L Jiao, N Shaw, W Liang, L Zhang, LW Hung, ... Acta Crystallographica Section D: Biological Crystallography 68 (5), 521-530, 2012 | 25 | 2012 |
Structural gymnastics of RAG-mediated DNA cleavage in V(D)J recombination H Ru, P Zhang, H Wu Current Opinion in Structural Biology 53, 178-186, 2018 | 21 | 2018 |
Structural and Functional Analysis of STING Sheds New Light on Cyclic di-GMP Mediated Immune Signaling Mechanism S Ouyang, X Song, Y Wang, H Ru, N Shaw, Y Jiang, F Niu, Y Zhu, W Qiu, ... Immunity 36 (6), 2012 | 5 | 2012 |
Characterization of T and B cell repertoire diversity in patients with RAG deficiency. Sci Immunol 1: eaah6109 YN Lee, F Frugoni, K Dobbs, I Tirosh, L Du, FA Ververs, H Ru, ... | 4 | 2016 |
Thermus thermophilus-derived protein tags that aid in preparation of insoluble viral proteins N Kondo, A Ebihara, H Ru, S Kuramitsu, A Iwamoto, Z Rao, Z Matsuda Analytical Biochemistry 385 (2), 278-285, 2009 | 4 | 2009 |
Promiscuity is not always bad H Ru, P Zhang, H Wu Molecular cell 54 (2), 208-209, 2014 | 3 | 2014 |
Structural biology and functional features of phage-derived depolymerase Depo32 on Klebsiella pneumoniae with K2 serotype capsular polysaccharides R Cai, Z Ren, R Zhao, Y Lu, X Wang, Z Guo, J Song, W Xiang, R Du, ... Microbiology Spectrum 11 (5), e05304-22, 2023 | 2 | 2023 |
Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1 W Liu, M Tang, J Wang, F Wang, G Song, X Zhang, S Wu, H Ru Cell Discovery 10 (1), 21, 2024 | 1 | 2024 |