Mechanisms of resistance to aminoglycoside antibiotics: overview and perspectives S Garneau-Tsodikova, KJ Labby Medchemcomm 7 (1), 11-27, 2016 | 540 | 2016 |
Target-and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers PC Trippier, K Jansen Labby, DD Hawker, JJ Mataka, RB Silverman Journal of medicinal chemistry 56 (8), 3121-3147, 2013 | 163 | 2013 |
Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections KJ Labby, S Garneau-Tsodikova Future medicinal chemistry 5 (11), 1285-1309, 2013 | 135 | 2013 |
Molecular mechanism for isoform-selective inhibition of acyl protein thioesterases 1 and 2 (APT1 and APT2) SJ Won, D Davda, KJ Labby, SY Hwang, R Pricer, JD Majmudar, ... ACS chemical biology 11 (12), 3374-3382, 2016 | 80 | 2016 |
Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis KJ Labby, SG Watsula, S Garneau-Tsodikova Natural product reports 32 (5), 641-653, 2015 | 75 | 2015 |
Harnessing redox cross-reactivity to profile distinct cysteine modifications JD Majmudar, AM Konopko, KJ Labby, CTMB Tom, JE Crellin, A Prakash, ... Journal of the American Chemical Society 138 (6), 1852-1859, 2016 | 56 | 2016 |
Intramolecular hydrogen bonding: a potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase KJ Labby, F Xue, JM Kraus, H Ji, J Mataka, H Li, P Martásek, LJ Roman, ... Bioorganic & medicinal chemistry 20 (7), 2435-2443, 2012 | 52 | 2012 |
Synthesis and evaluation of hetero-and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance Y Berkov-Zrihen, KD Green, KJ Labby, M Feldman, S Garneau-Tsodikova, ... Journal of medicinal chemistry 56 (13), 5613-5625, 2013 | 44 | 2013 |
Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations H Huang, H Ji, H Li, Q Jing, KJ Labby, P Martásek, LJ Roman, TL Poulos, ... Journal of the American Chemical Society 134 (28), 11559-11572, 2012 | 37 | 2012 |
Mechanisms of resistance to aminoglycoside antibiotics: overview and perspectives. Medchemcomm 7: 11–27 S Garneau-Tsodikova, KJ Labby | 22 | 2016 |
Redesign of substrate specificity and identification of the aminoglycoside binding residues of Eis from Mycobacterium tuberculosis BC Jennings, KJ Labby, KD Green, S Garneau-Tsodikova Biochemistry 52 (30), 5125-5132, 2013 | 20 | 2013 |
Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase F Xue, JM Kraus, KJ Labby, H Ji, J Mataka, G Xia, H Li, SL Delker, ... Journal of medicinal chemistry 54 (18), 6399-6403, 2011 | 20 | 2011 |
Chemoselective ratiometric imaging of protein S-sulfenylation CTMB Tom, JE Crellin, HF Motiwala, MB Stone, D Davda, W Walker, ... Chemical Communications 53 (53), 7385-7388, 2017 | 17 | 2017 |
Cyclopropyl-and methyl-containing inhibitors of neuronal nitric oxide synthase H Li, F Xue, JM Kraus II, H Ji, KJ Labby, J Mataka, SL Delker, P Martásek, ... Bioorganic & medicinal chemistry 21 (5), 1333-1343, 2013 | 17 | 2013 |
Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N ω-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus R Davydov, KJ Labby, SE Chobot, DA Lukoyanov, BR Crane, ... Biochemistry 53 (41), 6511-6519, 2014 | 16 | 2014 |
Methylated Nω-Hydroxy-l-arginine Analogues as Mechanistic Probes for the Second Step of the Nitric Oxide Synthase-Catalyzed Reaction K Jansen Labby, H Li, LJ Roman, P Martásek, TL Poulos, RB Silverman Biochemistry 52 (18), 3062-3073, 2013 | 16 | 2013 |
Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections. Future Med Chem 5: 1285–1309 KJ Labby, S Garneau-Tsodikova | 11 | 2013 |
Mechanisms of resistance to aminoglycoside antibiotics: Overview and perspectives. Medchemcomm. 2016; 7 (1): 11–27 S Garneau-Tsodikova, KJ Labby PubMed Abstract| Publisher Full Text| Free Full Text| F1000 Recommendation, 0 | 10 | |
Contextualizing chemistry in art and archaeology: inspiration for instructors American Chemical Society American Chemical Society, 2021 | 4 | 2021 |
Evolutionary genome mining for the discovery and engineering of natural product biosynthesis MG Chevrette, N Selem-Mojica, C Aguilar, K Labby, ED Bustos-Diaz, ... Engineering Natural Product Biosynthesis: Methods and Protocols, 129-155, 2022 | 2 | 2022 |