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Veerle Janssens
Veerle Janssens
Professor Cellular and Molecular Medicine
在 kuleuven.be 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
V Janssens, J Goris
Biochemical Journal 353 (3), 417-439, 2001
23242001
PP2A: the expected tumor suppressor
V Janssens, J Goris, C Van Hoof
Current opinion in genetics & development 15 (1), 34-41, 2005
5522005
PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail)
V Janssens, S Longin, J Goris
Trends in biochemical sciences 33 (3), 113-121, 2008
4822008
Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells
MHA Schmitz, M Held, V Janssens, JRA Hutchins, O Hudecz, E Ivanova, ...
Nature cell biology 12 (9), 886-893, 2010
3772010
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis
I Pastushenko, F Mauri, Y Song, F de Cock, B Meeusen, B Swedlund, ...
Nature 589 (7842), 448-455, 2021
2862021
Selection of protein phosphatase 2A regulatory subunits is mediated by the C terminus of the catalytic Subunit
S Longin, K Zwaenepoel, JV Louis, S Dilworth, J Goris, V Janssens
Journal of Biological Chemistry 282 (37), 26971-26980, 2007
2642007
Combination of hypoglycemia and metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3β-MCL-1 axis
M Elgendy, M Ciro, A Hosseini, J Weiszmann, L Mazzarella, E Ferrari, ...
Cancer cell 35 (5), 798-815. e5, 2019
2592019
The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity
W Sents, E Ivanova, C Lambrecht, D Haesen, V Janssens
The FEBS journal 280 (2), 644-661, 2013
2472013
Purification of Porcine Brain Protein Phosphatase 2A Leucine Carboxyl Methyltransferase and Cloning of the Human Homologue,
I De Baere, R Derua, V Janssens, C Van Hoof, E Waelkens, W Merlevede, ...
Biochemistry 38 (50), 16539-16547, 1999
2031999
Fructose-1, 6-bisphosphate couples glycolytic flux to activation of Ras
K Peeters, F Van Leemputte, B Fischer, BM Bonini, H Quezada, ...
Nature communications 8 (1), 922, 2017
1922017
The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase
J Jordens, V Janssens, S Longin, I Stevens, E Martens, G Bultynck, ...
Journal of Biological Chemistry 281 (10), 6349-6357, 2006
1522006
PP2AT61ɛ is an inhibitor of MAP4K3 in nutrient signaling to mTOR
L Yan, V Mieulet, D Burgess, GM Findlay, K Sully, J Procter, J Goris, ...
Molecular cell 37 (5), 633-642, 2010
1462010
An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator
S Longin, J Jordens, E Martens, I Stevens, V Janssens, E Rondelez, ...
Biochemical Journal 380 (1), 111-119, 2004
1462004
Structure, regulation, and pharmacological modulation of PP2A phosphatases
C Lambrecht, D Haesen, W Sents, E Ivanova, V Janssens
Phosphatase Modulators, 283-305, 2013
1392013
PP1 and PP2A phosphatases–cooperating partners in modulating retinoblastoma protein activation
V Kolupaeva, V Janssens
The FEBS journal 280 (2), 627-643, 2013
1312013
Mice lacking phosphatase PP2A subunit PR61/B’δ (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3β
JV Louis, E Martens, P Borghgraef, C Lambrecht, W Sents, S Longin, ...
Proceedings of the National Academy of Sciences 108 (17), 6957-6962, 2011
1262011
Physiologic functions of PP2A: Lessons from genetically modified mice
S Reynhout, V Janssens
Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1866 (1), 31-50, 2019
1252019
B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability
G Houge, D Haesen, LELM Vissers, S Mehta, MJ Parker, M Wright, J Vogt, ...
The Journal of clinical investigation 125 (8), 3051-3062, 2015
1232015
Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B “/PR72 subunit of protein phosphatase 2A
V Janssens, J Jordens, I Stevens, C Van Hoof, E Martens, H De Smedt, ...
Journal of Biological Chemistry 278 (12), 10697-10706, 2003
1222003
The B″/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A
JH Ahn, JY Sung, T McAvoy, A Nishi, V Janssens, J Goris, P Greengard, ...
Proceedings of the National Academy of Sciences 104 (23), 9876-9881, 2007
1162007
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