Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function JS Hawe, R Wilson, KT Schmid, L Zhou, LN Lakshmanan, BC Lehne, ... Nature genetics 54 (1), 18-29, 2022 | 75 | 2022 |
Robust CTCF-based chromatin architecture underpins epigenetic changes in the heart failure stress–gene response DP Lee, WLW Tan, CG Anene-Nzelu, CJM Lee, PY Li, TDA Luu, CX Chan, ... Circulation 139 (16), 1937-1956, 2019 | 48 | 2019 |
Epigenomes of human hearts reveal new genetic variants relevant for cardiac disease and phenotype WLW Tan, CG Anene-Nzelu, E Wong, CJM Lee, HS Tan, SJ Tang, ... Circulation research 127 (6), 761-777, 2020 | 37 | 2020 |
Genomic enhancers in cardiac development and disease CG Anene-Nzelu, MCJ Lee, WLW Tan, A Dashi, RSY Foo Nature Reviews Cardiology 19 (1), 7-25, 2022 | 24 | 2022 |
The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases NWS Chew, B Chong, CH Ng, G Kong, YH Chin, W Xiao, M Lee, YY Dan, ... Frontiers in Genetics 13, 971484, 2022 | 21 | 2022 |
Assigning distal genomic enhancers to cardiac disease–causing genes CG Anene-Nzelu, WLW Tan, CJM Lee, Z Wenhao, A Perrin, A Dashi, ... Circulation 142 (9), 910-912, 2020 | 10 | 2020 |
Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells MI Autio, E Motakis, A Perrin, TB Amin, Z Tiang, DV Do, J Wang, J Tan, ... Elife 13, e79592, 2024 | 6 | 2024 |
BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation DCP Wong, J Xiao, TW Chew, M Pan, CJM Lee, JW Ang, I Yow, ... Advanced Science 9 (31), 2202834, 2022 | 6 | 2022 |
Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity CY Tan, PS Chan, H Tan, SW Tan, CJM Lee, JW Wang, S Ye, H Werner, ... Journal of Translational Medicine 21 (1), 690, 2023 | 3 | 2023 |
Genome-wide CRISPR screen identifies an NF2-adherens junction mechanistic dependency for cardiac lineage CJM Lee, MI Autio, WH Zheng, Y Song, SC Wang, DCP Wong, J Xiao, ... Circulation, 2024 | 1 | 2024 |
Metabolome-wide association of carotid intima media thickness identifies FDX1 as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations N Sadhu, R Dalan, PR Jain, CJM Lee, LS Pakkiri, KY Tay, TH Mina, ... medRxiv, 2024.05. 14.24307316, 2024 | 1 | 2024 |
Disease and phenotype relevant genetic variants identified from histone acetylomes in human hearts WL Wen Tan, CG Anene-Nzelu, E Wong, HS Tan, P Bangfen, CJM Lee, ... bioRxiv, 536763, 2019 | 1 | 2019 |
TRIM35: A Proposed Gateway to p53-Induced Heart Failure Pathogenesis CJM Lee, RSY Foo Circulation Research 135 (2), 314-316, 2024 | | 2024 |
Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation Y Zhu, M Ackers-Johnson, MK Shanmugam, LS Pakkiri, CL Drum, Y Chen, ... Circulation 149 (23), 1833-1851, 2024 | | 2024 |
Coordination of focal adhesion nanostructure and mechano-signaling drives cardiomyocyte differentiation J Xiao, X Zhong, JW Ang, DCP Wong, CJM Lee, RSY Foo, ... bioRxiv, 2023.11. 13.566796, 2023 | | 2023 |
CTCF mediates the Activity-by-contact derived cis-regulatory hubs M Lee, L Mangnier, CC Padilla, DP Lee, W Tan, PY Li, WH Zheng, L Gan, ... bioRxiv, 2022.11. 04.515249, 2022 | | 2022 |
BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation (Adv. Sci. 31/2022) DCP Wong, J Xiao, TW Chew, M Pan, CJM Lee, JW Ang, I Yow, ... Advanced Science 9 (31), 2022 | | 2022 |
P-067: Systematic functional characterization for loss of function events cooperating with TP53 loss in high-risk 17p13 (del) multiple myeloma PJ Teoh, RDM Simoes, TH Chung, M Lee, R Foo, WJ Chng, C Mitsiades Clinical Lymphoma Myeloma and Leukemia 22, S72, 2022 | | 2022 |
GENOME-WIDE CRISPR SCREEN IDENTIFIES AN NF2-ADHERENS JUNCTION MECHANISTIC DEPENDENCY FOR CARDIAC LINEAGE LEECJIE MICK | | 2022 |
Disease and Phenotype-relevant Genetic Variants Identified From Histone Acetylomes in Human Hearts CG Anene Nzelu, W Tan, E Wong, M Lee, MI Autio, S Tan, P Bangfen, ... Circulation Research 125 (Suppl_1), A368-A368, 2019 | | 2019 |