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Chang Jie Mick Lee
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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
JS Hawe, R Wilson, KT Schmid, L Zhou, LN Lakshmanan, BC Lehne, ...
Nature genetics 54 (1), 18-29, 2022
752022
Robust CTCF-based chromatin architecture underpins epigenetic changes in the heart failure stress–gene response
DP Lee, WLW Tan, CG Anene-Nzelu, CJM Lee, PY Li, TDA Luu, CX Chan, ...
Circulation 139 (16), 1937-1956, 2019
482019
Epigenomes of human hearts reveal new genetic variants relevant for cardiac disease and phenotype
WLW Tan, CG Anene-Nzelu, E Wong, CJM Lee, HS Tan, SJ Tang, ...
Circulation research 127 (6), 761-777, 2020
372020
Genomic enhancers in cardiac development and disease
CG Anene-Nzelu, MCJ Lee, WLW Tan, A Dashi, RSY Foo
Nature Reviews Cardiology 19 (1), 7-25, 2022
242022
The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases
NWS Chew, B Chong, CH Ng, G Kong, YH Chin, W Xiao, M Lee, YY Dan, ...
Frontiers in Genetics 13, 971484, 2022
212022
Assigning distal genomic enhancers to cardiac disease–causing genes
CG Anene-Nzelu, WLW Tan, CJM Lee, Z Wenhao, A Perrin, A Dashi, ...
Circulation 142 (9), 910-912, 2020
102020
Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells
MI Autio, E Motakis, A Perrin, TB Amin, Z Tiang, DV Do, J Wang, J Tan, ...
Elife 13, e79592, 2024
62024
BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation
DCP Wong, J Xiao, TW Chew, M Pan, CJM Lee, JW Ang, I Yow, ...
Advanced Science 9 (31), 2202834, 2022
62022
Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
CY Tan, PS Chan, H Tan, SW Tan, CJM Lee, JW Wang, S Ye, H Werner, ...
Journal of Translational Medicine 21 (1), 690, 2023
32023
Genome-wide CRISPR screen identifies an NF2-adherens junction mechanistic dependency for cardiac lineage
CJM Lee, MI Autio, WH Zheng, Y Song, SC Wang, DCP Wong, J Xiao, ...
Circulation, 2024
12024
Metabolome-wide association of carotid intima media thickness identifies FDX1 as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations
N Sadhu, R Dalan, PR Jain, CJM Lee, LS Pakkiri, KY Tay, TH Mina, ...
medRxiv, 2024.05. 14.24307316, 2024
12024
Disease and phenotype relevant genetic variants identified from histone acetylomes in human hearts
WL Wen Tan, CG Anene-Nzelu, E Wong, HS Tan, P Bangfen, CJM Lee, ...
bioRxiv, 536763, 2019
12019
TRIM35: A Proposed Gateway to p53-Induced Heart Failure Pathogenesis
CJM Lee, RSY Foo
Circulation Research 135 (2), 314-316, 2024
2024
Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation
Y Zhu, M Ackers-Johnson, MK Shanmugam, LS Pakkiri, CL Drum, Y Chen, ...
Circulation 149 (23), 1833-1851, 2024
2024
Coordination of focal adhesion nanostructure and mechano-signaling drives cardiomyocyte differentiation
J Xiao, X Zhong, JW Ang, DCP Wong, CJM Lee, RSY Foo, ...
bioRxiv, 2023.11. 13.566796, 2023
2023
CTCF mediates the Activity-by-contact derived cis-regulatory hubs
M Lee, L Mangnier, CC Padilla, DP Lee, W Tan, PY Li, WH Zheng, L Gan, ...
bioRxiv, 2022.11. 04.515249, 2022
2022
BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation (Adv. Sci. 31/2022)
DCP Wong, J Xiao, TW Chew, M Pan, CJM Lee, JW Ang, I Yow, ...
Advanced Science 9 (31), 2022
2022
P-067: Systematic functional characterization for loss of function events cooperating with TP53 loss in high-risk 17p13 (del) multiple myeloma
PJ Teoh, RDM Simoes, TH Chung, M Lee, R Foo, WJ Chng, C Mitsiades
Clinical Lymphoma Myeloma and Leukemia 22, S72, 2022
2022
GENOME-WIDE CRISPR SCREEN IDENTIFIES AN NF2-ADHERENS JUNCTION MECHANISTIC DEPENDENCY FOR CARDIAC LINEAGE
LEECJIE MICK
2022
Disease and Phenotype-relevant Genetic Variants Identified From Histone Acetylomes in Human Hearts
CG Anene Nzelu, W Tan, E Wong, M Lee, MI Autio, S Tan, P Bangfen, ...
Circulation Research 125 (Suppl_1), A368-A368, 2019
2019
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