The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus SM Currie, EG Findlay, BJ McHugh, A Mackellar, T Man, D Macmillan, ... PloS one 8 (8), e73659, 2013 | 217 | 2013 |
IFN-γ–producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain A Villegas-Mendez, R Greig, TN Shaw, JB De Souza, E Gwyer Findlay, ... The Journal of Immunology 189 (2), 968-979, 2012 | 213 | 2012 |
Cationic host defence peptides: potential as antiviral therapeutics E Gwyer Findlay, SM Currie, DJ Davidson BioDrugs 27, 479-493, 2013 | 169 | 2013 |
Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans SM Currie, E Gwyer Findlay, AJ McFarlane, PM Fitch, B Böttcher, ... The Journal of Immunology 196 (6), 2699-2710, 2016 | 157 | 2016 |
Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection EG Findlay, R Greig, JS Stumhofer, JCR Hafalla, JB De Souza, CJ Saris, ... The Journal of Immunology 185 (4), 2482-2492, 2010 | 141 | 2010 |
Antiviral potential of cathelicidins PG Barlow, EG Findlay, SM Currie, DJ Davidson Future microbiology 9 (1), 55-73, 2014 | 109 | 2014 |
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation D Minns, KJ Smith, V Alessandrini, G Hardisty, L Melrose, ... Nature communications 12 (1), 1285, 2021 | 108 | 2021 |
Cathelicidin Host Defence Peptide Augments Clearance of Pulmonary Pseudomonas aeruginosa Infection by Its Influence on Neutrophil Function In Vivo PE Beaumont, B McHugh, E Gwyer Findlay, A Mackellar, KJ Mackenzie, ... PloS one 9 (6), e99029, 2014 | 103 | 2014 |
Macrophage‐mediated inflammation and disease: a focus on the lung E Gwyer Findlay, T Hussell Mediators of inflammation 2012 (1), 140937, 2012 | 96 | 2012 |
IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals A Villegas-Mendez, JB de Souza, SW Lavelle, E Gwyer Findlay, TN Shaw, ... PLoS pathogens 9 (4), e1003293, 2013 | 76 | 2013 |
Orchestration of adaptive T cell responses by neutrophil granule contents D Minns, KJ Smith, EG Findlay Mediators of inflammation 2019 (1), 8968943, 2019 | 74 | 2019 |
The outcome of neutrophil-T cell contact differs depending on activation status of both cell types D Minns, KJ Smith, G Hardisty, AG Rossi, E Gwyer Findlay Frontiers in Immunology 12, 633486, 2021 | 48 | 2021 |
Cathelicidin is a “fire alarm”, generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa BJ McHugh, R Wang, HN Li, PE Beaumont, R Kells, H Stevens, L Young, ... PLoS Pathogens 15 (4), e1007694, 2019 | 48 | 2019 |
OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis E Gwyer Findlay, L Danks, J Madden, MM Cavanagh, K McNamee, ... Proceedings of the National Academy of Sciences 111 (6), 2289-2294, 2014 | 45 | 2014 |
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics TM Quinn, EE Gaughan, A Bruce, J Antonelli, R O'Connor, F Li, ... EBioMedicine 76, 2022 | 44 | 2022 |
IL-27 Receptor Signaling Regulates Memory CD4+ T Cell Populations and Suppresses Rapid Inflammatory Responses during Secondary Malaria Infection E Gwyer Findlay, A Villegas-Mendez, N O'Regan, JB de Souza, LM Grady, ... Infection and immunity 82 (1), 10-20, 2014 | 40 | 2014 |
High purity isolation of low density neutrophils casts doubt on their exceptionality in health and disease GR Hardisty, F Llanwarne, D Minns, JL Gillan, DJ Davidson, ... Frontiers in Immunology 12, 625922, 2021 | 38 | 2021 |
IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection E Gwyer Findlay, A Villegas-Mendez, JB de Souza, CA Inkson, TN Shaw, ... The Journal of Immunology 190 (9), 4553-4561, 2013 | 37 | 2013 |
Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy EG Findlay, AJ Currie, A Zhang, J Ovciarikova, L Young, H Stevens, ... Oncoimmunology, 2019 | 35 | 2019 |
An inhaled galectin-3 inhibitor in COVID-19 pneumonitis: a phase Ib/IIa randomized controlled clinical trial (DEFINE) EE Gaughan, TM Quinn, A Mills, AM Bruce, J Antonelli, AC MacKinnon, ... American Journal of Respiratory and Critical Care Medicine 207 (2), 138-149, 2023 | 29 | 2023 |