Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome T Hearn, GL Renforth, C Spalluto, NA Hanley, K Piper, S Brickwood, ... Nature genetics 31 (1), 79-83, 2002 | 358 | 2002 |
Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes T Hearn, C Spalluto, VJ Phillips, GL Renforth, N Copin, NA Hanley, ... Diabetes 54 (5), 1581-1587, 2005 | 261 | 2005 |
Derivation of human embryonic germ cells: an alternative source of pluripotent stem cells L Turnpenny, S Brickwood, CM Spalluto, K Piper, IT Cameron, DI Wilson, ... Stem Cells 21 (5), 598-609, 2003 | 189 | 2003 |
A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection C Blume, CL Jackson, CM Spalluto, J Legebeke, L Nazlamova, F Conforti, ... Nature genetics 53 (2), 205-214, 2021 | 149 | 2021 |
Dysregulation of Antiviral Function of CD8+ T Cells in the Chronic Obstructive Pulmonary Disease Lung. Role of the PD-1–PD-L1 Axis RT McKendry, CM Spalluto, H Burke, B Nicholas, D Cellura, ... American journal of respiratory and critical care medicine 193 (6), 642-651, 2016 | 136 | 2016 |
Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif–containing proteins C10orf90 and KIAA1731 VJ Knorz, C Spalluto, M Lessard, TL Purvis, FF Adigun, GB Collin, ... Molecular biology of the cell 21 (21), 3617-3629, 2010 | 127 | 2010 |
Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells L Turnpenny, CM Spalluto, RM Perrett, M O'Shea, KP Hanley, IT Cameron, ... Stem Cells 24 (2), 212-220, 2006 | 100 | 2006 |
Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations JA Tree, JE Turnbull, KR Buttigieg, MJ Elmore, N Coombes, J Hogwood, ... British Journal of Pharmacology 178 (3), 626-635, 2021 | 99 | 2021 |
Inflammatory phenotyping predicts clinical outcome in COVID-19 H Burke, A Freeman, DC Cellura, BL Stuart, NJ Brendish, S Poole, ... Respiratory research 21, 1-9, 2020 | 82 | 2020 |
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... ACS central science 8 (5), 527-545, 2022 | 80 | 2022 |
Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10q J Guy, C Spalluto, A McMurray, T Hearn, M Crosier, L Viggiano, V Miolla, ... Human molecular genetics 9 (13), 2029-2042, 2000 | 75 | 2000 |
Dynamics of IFN-β responses during respiratory viral infection. Insights for therapeutic strategies A Watson, CM Spalluto, C McCrae, D Cellura, H Burke, D Cunoosamy, ... American journal of respiratory and critical care medicine 201 (1), 83-94, 2020 | 67 | 2020 |
Nek2 localises to the distal portion of the mother centriole/basal body and is required for timely cilium disassembly at the G2/M transition C Spalluto, DI Wilson, T Hearn European journal of cell biology 91 (9), 675-686, 2012 | 67 | 2012 |
Narrowing the critical region within 11q24–qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis HM Phillips, GL Renforth, C Spalluto, T Hearn, ARJ Curtis, L Craven, ... Genomics 79 (4), 475-478, 2002 | 66 | 2002 |
Evidence for reciliation of RPE1 cells in late G1 phase, and ciliary localisation of cyclin B1 C Spalluto, DI Wilson, T Hearn FEBS open bio 3, 334-340, 2013 | 55 | 2013 |
Viral infection of human lung macrophages increases PDL1 expression via IFNβ KJ Staples, B Nicholas, RT McKendry, CM Spalluto, JC Wallington, ... PloS one 10 (3), e0121527, 2015 | 54 | 2015 |
Identification of SCML2, a second human gene homologous to thedrosophila Sex comb on midleg (Scm): A new gene cluster on Xp22 E Montini, G Buchner, C Spalluto, G Andolfi, A Caruso, JT den Dunnen, ... Genomics 58 (1), 65-72, 1999 | 50 | 1999 |
Evolution of chromosome Y in primates N Archidiacono, CT Storlazzi, C Spalluto, AS Ricco, R Marzella, M Rocchi Chromosoma 107 (4), 241-246, 1998 | 45 | 1998 |
The Role of Non-Typeable Haemophilus influenzae Biofilms in Chronic Obstructive Pulmonary Disease JR Weeks, KJ Staples, CM Spalluto, A Watson, TMA Wilkinson Frontiers in cellular and infection microbiology 11, 720742, 2021 | 40 | 2021 |
Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1 TL Purvis, T Hearn, C Spalluto, VJ Knorz, KP Hanley, T Sanchez-Elsner, ... Gene 460 (1-2), 20-29, 2010 | 40 | 2010 |