Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo Z Shao, BJ Lee, É Rouleau-Turcotte, MF Langelier, X Lin, VM Estes, ... Nucleic acids research 48 (17), 9694-9709, 2020 | 66 | 2020 |
PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites X Lin, W Jiang, J Rudolph, BJ Lee, K Luger, S Zha Nucleic Acids Research 50 (7), 3958-3973, 2022 | 34 | 2022 |
Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation C Li, L Kan, Y Chen, X Zheng, W Li, W Zhang, L Cao, X Lin, S Ji, S Huang, ... Cell Research 25 (10), 1152-1170, 2015 | 34 | 2015 |
Phosphorylation at S2053 in murine (S2056 in human) DNA-PKcs is dispensable for lymphocyte development and class switch recombination W Jiang, VM Estes, XS Wang, Z Shao, BJ Lee, X Lin, JL Crowe, S Zha The Journal of Immunology 203 (1), 178-187, 2019 | 33 | 2019 |
Clinical PARP inhibitors allosterically induce PARP2 retention on DNA MF Langelier, X Lin, S Zha, JM Pascal Science advances 9 (12), eadf7175, 2023 | 28 | 2023 |
CtIP is essential for early B cell proliferation and development in mice X Liu, XS Wang, BJ Lee, FK Wu-Baer, X Lin, Z Shao, VM Estes, J Gautier, ... Journal of Experimental Medicine 216 (7), 1648-1663, 2019 | 19 | 2019 |
Ubiquitin E3 ligase dSmurf is essential for Wts protein turnover and Hippo signaling L Cao, P Wang, Y Gao, X Lin, F Wang, S Wu Biochemical and Biophysical Research Communications 454 (1), 167-171, 2014 | 17 | 2014 |
Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner Z Shao, BJ Lee, H Zhang, X Lin, C Li, W Jiang, N Chirathivat, S Gershik, ... Proceedings of the National Academy of Sciences 120 (31), e2301972120, 2023 | 12 | 2023 |
Drosophila eye developmental defect caused by elevation of the activity of the LIM-homeodomain protein, Lmx1a, requires its association with the Co-activator Chip P Wang, Y Chen, C Li, R Zhao, F Wang, X Lin, L Cao, S Li, L Hu, Y Gao, ... Biochemical and biophysical research communications 470 (1), 29-34, 2016 | 8 | 2016 |
FATC domain deletion compromises ATM protein stability, blocks lymphocyte development, and promotes lymphomagenesis M Milanovic, Z Shao, VM Estes, XS Wang, D Menolfi, X Lin, BJ Lee, J Xu, ... The Journal of Immunology 206 (6), 1228-1239, 2021 | 6 | 2021 |
Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging H Zhang, X Lin, S Zha Biochemical Society Transactions 50 (4), 1169-1177, 2022 | 4 | 2022 |
Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts X Lin, D Gupta, A Vaitsiankova, SK Bhandari, KSK Leung, D Menolfi, ... Molecular Cell 84 (20), 3916-3931. e7, 2024 | 3 | 2024 |
The SCF ubiquitin ligase Slimb controls Nerfin-1 turnover in Drosophila X Lin, F Wang, Y Li, C Zhai, G Wang, X Zhang, Y Gao, T Yi, D Sun, S Wu Biochemical and biophysical research communications 495 (1), 629-633, 2018 | 3 | 2018 |
XRCC1 mediates PARP1-and PAR-dependent recruitment of PARP2 to DNA damage sites X Lin, KSK Leung, KF Wolfe, BJ Lee, S Zha bioRxiv, 2024.05. 14.594230, 2024 | | 2024 |