| RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS Y Ito, D Ofengeim, A Najafov, S Das, S Saberi, Y Li, J Hitomi, H Zhu, ... Science 353 (6299), 603-608, 2016 | 527 | 2016 |
| Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis J Geng, Y Ito, L Shi, P Amin, J Chu, AT Ouchida, AK Mookhtiar, H Zhao, ... Nature communications 8 (1), 359, 2017 | 249 | 2017 |
| PRMT5 regulates DNA repair by controlling the alternative splicing of histone-modifying enzymes PJ Hamard, GE Santiago, F Liu, DL Karl, C Martinez, N Man, ... Cell reports 24 (10), 2643-2657, 2018 | 163 | 2018 |
| TAM kinases promote necroptosis by regulating oligomerization of MLKL A Najafov, AK Mookhtiar, HS Luu, A Ordureau, H Pan, PP Amin, Y Li, Q Lu, ... Molecular cell 75 (3), 457-468. e4, 2019 | 109 | 2019 |
| PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP H Wang, H Meng, X Li, K Zhu, K Dong, AK Mookhtiar, H Wei, Y Li, SC Sun, ... Proceedings of the National Academy of Sciences 114 (45), 11944-11949, 2017 | 109 | 2017 |
| Drug repositioning in glioblastoma: a pathway perspective SK Tan, A Jermakowicz, AK Mookhtiar, CB Nemeroff, SC Schürer, ... Frontiers in pharmacology 9, 218, 2018 | 97 | 2018 |
| ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC SA Dziedzic, Z Su, V Jean Barrett, A Najafov, AK Mookhtiar, P Amin, ... Nature cell biology 20 (1), 58-68, 2018 | 91 | 2018 |
| Long non‐coding RNA: a versatile regulator of the nuclear factor‐κB signalling circuit X Mao, Z Su, AK Mookhtiar Immunology 150 (4), 379-388, 2017 | 75 | 2017 |
| BRAF and AXL oncogenes drive RIPK3 expression loss in cancer A Najafov, IK Zervantonakis, AK Mookhtiar, P Greninger, RJ March, ... PLoS biology 16 (8), e2005756, 2018 | 71 | 2018 |
| PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2 F Liu, Y Xu, X Lu, PJ Hamard, DL Karl, N Man, AK Mookhtiar, C Martinez, ... Nucleic acids research 48 (6), 2956-2968, 2020 | 48 | 2020 |
| RIPK1 promotes energy sensing by the mTORC1 pathway A Najafov, HS Luu, AK Mookhtiar, L Mifflin, H Xia, PP Amin, A Ordureau, ... Molecular cell 81 (2), 370-385. e7, 2021 | 32 | 2021 |
| RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells J Sun, G Gaidosh, Y Xu, A Mookhtiar, N Man, PR Cingaram, E Blumenthal, ... Oncogene 40 (40), 5950-5962, 2021 | 13 | 2021 |
| The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression G Mas, N Man, Y Nakata, C Martinez-Caja, D Karl, F Beckedorff, F Tamiro, ... The Journal of clinical investigation 133 (13), 2023 | 3 | 2023 |
| CARM1 inhibition: evaluation of response and efficacy in acute myeloid leukemia AK Mookhtiar, S Greenblatt, N Man, D Karl, V Stathias, S Schurer, ... Blood 132, 2719, 2018 | 1 | 2018 |
| Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity H Itonaga, AK Mookhtiar, SM Greenblatt, F Liu, C Martinez, D Bilbao, ... Nature Communications 15 (1), 3415, 2024 | | 2024 |
| Arginine Methylation of BRD4 By CARM1 Regulates Its Function in AML AK Mookhtiar, H Itonaga, S Greenblatt, C Martinez, J Sun, KL Hossack, ... Blood 142, 4112, 2023 | | 2023 |
| Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2 H Itonaga, AK Mookhtiar, S Greenblatt, F Liu, C Martinez, R Grozovsky, ... Blood 140 (Supplement 1), 3021-3022, 2022 | | 2022 |
| The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks GM Martin, N Man, D Karl, C Martinez, S Duffort, H Itonaga, AK Mookhtiar, ... Blood 136, 13, 2020 | | 2020 |
