Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing C Redin, B Gérard, J Lauer, Y Herenger, J Muller, A Quartier, ... Journal of medical genetics 51 (11), 724-736, 2014 | 295 | 2014 |
Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma T Strub, S Giuliano, T Ye, C Bonet, C Keime, D Kobi, S Le Gras, ... Oncogene 30 (20), 2319-2332, 2011 | 290 | 2011 |
Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA A Fadloun, S Le Gras, B Jost, C Ziegler-Birling, H Takahashi, E Gorab, ... Nature structural & molecular biology 20 (3), 332-338, 2013 | 251 | 2013 |
A strategy for direct mapping and identification of mutations by whole-genome sequencing S Zuryn, S Le Gras, K Jamet, S Jarriault Genetics 186 (1), 427-430, 2010 | 197 | 2010 |
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells P Laurette, T Strub, D Koludrovic, C Keime, S Le Gras, H Seberg, ... Elife 4, e06857, 2015 | 194 | 2015 |
Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells L Delacroix, E Moutier, G Altobelli, S Legras, O Poch, MA Choukrallah, ... Molecular and cellular biology, 2010 | 185 | 2010 |
Histone propionylation is a mark of active chromatin AF Kebede, A Nieborak, LZ Shahidian, S Le Gras, F Richter, DA Gomez, ... Nature structural & molecular biology 24 (12), 1048-1056, 2017 | 177 | 2017 |
Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process NEH Mimouni, I Paiva, AL Barbotin, FE Timzoura, D Plassard, S Le Gras, ... Cell metabolism 33 (3), 513-530. e8, 2021 | 148 | 2021 |
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation H Neyret-Kahn, M Benhamed, T Ye, S Le Gras, JC Cossec, P Lapaquette, ... Genome research 23 (10), 1563-1579, 2013 | 141 | 2013 |
A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement MK Prasad, V Geoffroy, S Vicaire, B Jost, M Dumas, S Le Gras, M Switala, ... Journal of medical genetics 53 (2), 98-110, 2016 | 138 | 2016 |
Targeted high-throughput sequencing for diagnosis of genetically heterogeneous diseases: efficient mutation detection in Bardet-Biedl and Alström syndromes C Redin, S Le Gras, O Mhamdi, V Geoffroy, C Stoetzel, MC Vincent, ... Journal of medical genetics 49 (8), 502-512, 2012 | 134 | 2012 |
Next generation sequencing for molecular diagnosis of neuromuscular diseases N Vasli, J Böhm, S Le Gras, J Muller, C Pizot, B Jost, A Echaniz-Laguna, ... Acta neuropathologica 124, 273-283, 2012 | 109 | 2012 |
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice M Achour, S Le Gras, C Keime, F Parmentier, FX Lejeune, AL Boutillier, ... Human molecular genetics 24 (12), 3481-3496, 2015 | 102 | 2015 |
Bcl11b represses a mature T‐cell gene expression program in immature CD4+CD8+ thymocytes P Kastner, S Chan, WK Vogel, LJ Zhang, A Topark‐Ngarm, O Golonzhka, ... European journal of immunology 40 (8), 2143-2154, 2010 | 97 | 2010 |
Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3 A Burton, V Brochard, C Galan, ER Ruiz-Morales, Q Rovira, ... Nature cell biology 22 (7), 767-778, 2020 | 95 | 2020 |
MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity D Latrasse, T Jégu, H Li, A de Zelicourt, C Raynaud, S Legras, A Gust, ... Genome biology 18, 1-19, 2017 | 95 | 2017 |
The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells AS Geimer Le Lay, A Oravecz, J Mastio, C Jung, P Marchal, C Ebel, ... Science signaling 7 (317), ra28-ra28, 2014 | 89 | 2014 |
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL R Jeannet, J Mastio, A Macias-Garcia, A Oravecz, T Ashworth, ... Blood, The Journal of the American Society of Hematology 116 (25), 5443-5454, 2010 | 88 | 2010 |
Genes and pathways regulated by androgens in human neural cells, potential candidates for the male excess in autism spectrum disorder A Quartier, L Chatrousse, C Redin, C Keime, N Haumesser, ... Biological Psychiatry 84 (4), 239-252, 2018 | 74 | 2018 |
Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA B Herquel, K Ouararhni, I Martianov, S Le Gras, T Ye, C Keime, T Lerouge, ... Nature structural & molecular biology 20 (3), 339, 2013 | 74 | 2013 |