Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug AG Ramsay, AJ Johnson, AM Lee, G Gorgün, R Le Dieu, W Blum, JC Byrd, ... The Journal of clinical investigation 118 (7), 2427-2437, 2008 | 730 | 2008 |
T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production JC Riches, JK Davies, F McClanahan, R Fatah, S Iqbal, S Agrawal, ... Blood, The Journal of the American Society of Hematology 121 (9), 1612-1621, 2013 | 590 | 2013 |
Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma A Ene–Obong, AJ Clear, J Watt, J Wang, R Fatah, JC Riches, JF Marshall, ... Gastroenterology 145 (5), 1121-1132, 2013 | 552 | 2013 |
Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible … AG Ramsay, AJ Clear, R Fatah, JG Gribben Blood, The Journal of the American Society of Hematology 120 (7), 1412-1421, 2012 | 433 | 2012 |
Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy AG Ramsay, AJ Clear, G Kelly, R Fatah, J Matthews, F MacDougall, ... Blood, The Journal of the American Society of Hematology 114 (21), 4713-4720, 2009 | 286 | 2009 |
Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts R Le Dieu, DC Taussig, AG Ramsay, R Mitter, F Miraki-Moud, R Fatah, ... Blood, The Journal of the American Society of Hematology 114 (18), 3909-3916, 2009 | 244 | 2009 |
Effects of alternative dietary substrates on competition between human colonic bacteria in an anaerobic fermentor system SH Duncan, KP Scott, AG Ramsay, HJM Harmsen, GW Welling, ... Applied and environmental microbiology 69 (2), 1136-1142, 2003 | 209 | 2003 |
HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin αvβ6 AG Ramsay, MD Keppler, M Jazayeri, GJ Thomas, M Parsons, S Violette, ... Cancer research 67 (11), 5275-5284, 2007 | 174 | 2007 |
Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting … AJ Clear, AM Lee, M Calaminici, AG Ramsay, KJ Morris, S Hallam, ... Blood, The Journal of the American Society of Hematology 115 (24), 5053-5056, 2010 | 163 | 2010 |
Chronic lymphocytic leukemia cells induce defective LFA-1–directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide AG Ramsay, R Evans, S Kiaii, L Svensson, N Hogg, JG Gribben Blood, The Journal of the American Society of Hematology 121 (14), 2704-2714, 2013 | 161 | 2013 |
Eμ-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction G Gorgun, AG Ramsay, TAW Holderried, D Zahrieh, R Le Dieu, F Liu, ... Proceedings of the National Academy of Sciences 106 (15), 6250-6255, 2009 | 151 | 2009 |
Immune checkpoint blockade immunotherapy to activate anti‐tumour T‐cell immunity AG Ramsay British journal of haematology 162 (3), 313-325, 2013 | 150 | 2013 |
Integrin trafficking and its role in cancer metastasis AG Ramsay, JF Marshall, IR Hart Cancer and Metastasis Reviews 26, 567-578, 2007 | 150 | 2007 |
Tumor microenvironment (TME)-driven immune suppression in B cell malignancy NS Nicholas, B Apollonio, AG Ramsay Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (3), 471-482, 2016 | 143 | 2016 |
Substrate-driven gene expression in Roseburia inulinivorans: Importance of inducible enzymes in the utilization of inulin and starch KP Scott, JC Martin, C Chassard, M Clerget, J Potrykus, G Campbell, ... Proceedings of the National Academy of Sciences 108 (supplement_1), 4672-4679, 2011 | 140 | 2011 |
Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation S Kiaii, AJ Clear, AG Ramsay, D Davies, A Sangaralingam, A Lee, ... Journal of clinical oncology 31 (21), 2654-2661, 2013 | 120 | 2013 |
Cell-associated α-amylases of butyrate-producing Firmicute bacteria from the human colon AG Ramsay, KP Scott, JC Martin, MT Rincon, HJ Flint Microbiology 152 (11), 3281-3290, 2006 | 119 | 2006 |
Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations JC Riches, CJ O’Donovan, SJ Kingdon, F McClanahan, AJ Clear, ... Blood, The Journal of the American Society of Hematology 123 (26), 4101-4110, 2014 | 109 | 2014 |
Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic … TD Shanafelt, AG Ramsay, CS Zent, JF Leis, HW Tun, TG Call, B LaPlant, ... Blood, The Journal of the American Society of Hematology 121 (20), 4137-4141, 2013 | 107 | 2013 |
How does lenalidomide target the chronic lymphocytic leukemia microenvironment? AP Kater, SH Tonino, A Egle, AG Ramsay Blood, The Journal of the American Society of Hematology 124 (14), 2184-2189, 2014 | 79 | 2014 |