The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome M Sebaihia, BW Wren, P Mullany, NF Fairweather, N Minton, R Stabler, ... Nature genetics 38 (7), 779-786, 2006 | 1043 | 2006 |
The role of toxin A and toxin B in Clostridium difficile infection SA Kuehne, ST Cartman, JT Heap, ML Kelly, A Cockayne, NP Minton Nature 467 (7316), 711-713, 2010 | 947 | 2010 |
The ClosTron: a universal gene knock-out system for the genus Clostridium JT Heap, OJ Pennington, ST Cartman, GP Carter, NP Minton Journal of microbiological methods 70 (3), 452-464, 2007 | 829 | 2007 |
The pMTL nic− cloning vectors. I. Improved pUC polylinker regions to facilitate the use of sonicated DNA for nucleotide sequencing SP Chambers, SE Prior, DA Barstow, NP Minton Gene 68 (1), 139-149, 1988 | 560 | 1988 |
A modular system for Clostridium shuttle plasmids JT Heap, OJ Pennington, ST Cartman, NP Minton Journal of microbiological methods 78 (1), 79-85, 2009 | 554 | 2009 |
The ClosTron: mutagenesis in Clostridium refined and streamlined JT Heap, SA Kuehne, M Ehsaan, ST Cartman, CM Cooksley, JC Scott, ... Journal of microbiological methods 80 (1), 49-55, 2010 | 512 | 2010 |
Improved plasmid vectors for the isolation of translational lac gene fusions NP Minton Gene 31 (1-3), 269-273, 1984 | 388 | 1984 |
Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier D Purdy, TAT O'Keeffe, M Elmore, M Herbert, A McLeod, M Bokori‐Brown, ... Molecular microbiology 46 (2), 439-452, 2002 | 348 | 2002 |
Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile T Ðapa, R Leuzzi, YK Ng, ST Baban, R Adamo, SA Kuehne, M Scarselli, ... Journal of bacteriology 195 (3), 545-555, 2013 | 322 | 2013 |
Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis SC Liu, NP Minton, AJ Giaccia, JM Brown Gene therapy 9 (4), 291-296, 2002 | 304 | 2002 |
Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between the tcdC Genotype and Toxin Production ST Cartman, ML Kelly, D Heeg, JT Heap, NP Minton Applied and environmental microbiology 78 (13), 4683-4690, 2012 | 293 | 2012 |
Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes M Sebaihia, MW Peck, NP Minton, NR Thomson, MTG Holden, ... Genome research 17 (7), 1082-1092, 2007 | 292 | 2007 |
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954 JA Bridgewater, CJ Springer, RJ Knox, NP Minton, NP Michael, ... European journal of cancer 31 (13-14), 2362-2370, 1995 | 267 | 1995 |
Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment MJ Lemmon, P Van Zijl, ME Fox, ML Mauchline, AJ Giaccia, NP Minton, ... Gene therapy 4 (8), 791-796, 1997 | 263 | 1997 |
Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain SA Kuehne, MM Collery, ML Kelly, ST Cartman, A Cockayne, NP Minton The Journal of infectious diseases 209 (1), 83-86, 2014 | 251 | 2014 |
Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker JT Heap, M Ehsaan, CM Cooksley, YK Ng, ST Cartman, K Winzer, ... Nucleic acids research 40 (8), e59-e59, 2012 | 245 | 2012 |
Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia. ME Fox, MJ Lemmon, ML Mauchline, TO Davis, AJ Giaccia, NP Minton, ... Gene therapy 3 (2), 173-178, 1996 | 245 | 1996 |
Femtomolar sensitivity of a NO sensor from Clostridium botulinum P Nioche, V Berka, J Vipond, N Minton, AL Tsai, CS Raman Science 306 (5701), 1550-1553, 2004 | 241 | 2004 |
Metabolic engineering of Clostridium autoethanogenum for selective alcohol production F Liew, AM Henstra, M Kӧpke, K Winzer, SD Simpson, NP Minton Metabolic engineering 40, 104-114, 2017 | 226 | 2017 |
Clostridia in cancer therapy NP Minton Nature Reviews Microbiology 1 (3), 237-242, 2003 | 218 | 2003 |