Tumour stem cells and drug resistance M Dean, T Fojo, S Bates Nature Reviews Cancer 5 (4), 275-284, 2005 | 4481 | 2005 |
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function MF Egan, M Kojima, JH Callicott, TE Goldberg, BS Kolachana, A Bertolino, ... Cell 112 (2), 257-269, 2003 | 4455 | 2003 |
Identification of the cystic fibrosis gene: chromosome walking and jumping JM Rommens, MC Iannuzzi, B Kerem, ML Drumm, G Melmer, M Dean, ... Science 245 (4922), 1059-1065, 1989 | 4269 | 1989 |
The human ATP-binding cassette (ABC) transporter superfamily M Dean, A Rzhetsky, R Allikmets Genome Research 11 (7), 1156-1166, 2001 | 3988 | 2001 |
Identification of the von Hippel-Lindau disease tumor suppressor gene F Latif, K Tory, J Gnarra, M Yao, FM Duh, ML Orcutt, T Stackhouse, ... Science 260 (5112), 1317-1320, 1993 | 3445 | 1993 |
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene M Dean, M Carrington, C Winkler, GA Huttley, MW Smith, R Allikmets, ... Science 273 (5283), 1856-1862, 1996 | 3186 | 1996 |
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome H Hahn, C Wicking, PG Zaphiropoulos, MR Gailani, S Shanley, ... Cell 85 (6), 841-851, 1996 | 2387 | 1996 |
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration GS Hageman, DH Anderson, LV Johnson, LS Hancox, AJ Taiber, ... Proceedings of the National Academy of Sciences 102 (20), 7227-7232, 2005 | 2260 | 2005 |
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas L Schmidt, FM Duh, F Chen, T Kishida, G Glenn, P Choyke, SW Scherer, ... Nature genetics 16 (1), 68-73, 1997 | 1825 | 1997 |
A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Starqardt macular dystrophy R Allikmets, N Singh, H Sun, NF Shroyer, A Hutchinson, A Chidambaram, ... Nature genetics 15 (3), 236-246, 1997 | 1640 | 1997 |
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration B Gold, JE Merriam, J Zernant, LS Hancox, AJ Taiber, K Gehrs, K Cramer, ... Nature genetics 38 (4), 458-462, 2006 | 1295 | 2006 |
The genome of the sea urchin Strongylocentrotus purpuratus E Sodergren, GM Weinstock, EH Davidson, RA Cameron, RA Gibbs, ... Science 314 (5801), 941, 2006 | 1199 | 2006 |
Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression MW Smith, M Dean, M Carrington, C Winkler, GA Huttley, DA Lomb, ... Science 277 (5328), 959-965, 1997 | 1134 | 1997 |
Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration R Allikmets, NF Shroyer, N Singh, JM Seddon, RA Lewis, PS Bernstein, ... Science 277 (5333), 1805-1807, 1997 | 1129 | 1997 |
A Human Placenta-specific ATP-Binding Cassette Gene (ABCP) on Chromosome 4q22 That Is Involved in Multidrug Resistance R Allikmets, LM Schriml, A Hutchinson, V Romano-Spica, M Dean Cancer research 58 (23), 5337-5339, 1998 | 1105 | 1998 |
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes K Miyake, L Mickley, T Litman, Z Zhan, R Robey, B Cristensen, M Brangi, ... Cancer research 59 (1), 8-13, 1999 | 1031 | 1999 |
The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas MR Gailani, M Ståhle-Bäckdahl, DJ Leffell, M Glyn, PG Zaphiropoulos, ... Nature genetics 14 (1), 78-81, 1996 | 938 | 1996 |
Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant C Winkler, W Modi, MW Smith, GW Nelson, X Wu, M Carrington, M Dean, ... Science 279 (5349), 389-393, 1998 | 931 | 1998 |
Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation J Campisi, HE Gray, AB Pardee, M Dean, GE Sonenshein Cell 36 (2), 241-247, 1984 | 889 | 1984 |
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption MH Lee, K Lu, S Hazard, H Yu, S Shulenin, H Hidaka, H Kojima, ... Nature genetics 27 (1), 79-83, 2001 | 809 | 2001 |