The tumorigenicity of human embryonic and induced pluripotent stem cells U Ben-David, N Benvenisty Nature Reviews Cancer 11 (4), 268-277, 2011 | 1042 | 2011 |
Identification and classification of chromosomal aberrations in human induced pluripotent stem cells Y Mayshar, U Ben-David, N Lavon, JC Biancotti, B Yakir, AT Clark, K Plath, ... Cell stem cell 7 (4), 521-531, 2010 | 883 | 2010 |
Genetic and transcriptional evolution alters cancer cell line drug response U Ben-David, B Siranosian, G Ha, H Tang, Y Oren, K Hinohara, ... Nature 560 (7718), 325-330, 2018 | 821 | 2018 |
Patient-derived xenografts undergo mouse-specific tumor evolution U Ben-David, G Ha, YY Tseng, NF Greenwald, C Oh, J Shih, ... Nature genetics 49 (11), 1567-1575, 2017 | 714 | 2017 |
Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ... Cancer discovery 6 (8), 914-929, 2016 | 654 | 2016 |
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ... Nature cancer 1 (2), 235-248, 2020 | 548 | 2020 |
Context is everything: aneuploidy in cancer U Ben-David, A Amon Nature Reviews Genetics 21 (1), 44-62, 2020 | 536 | 2020 |
Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen U Ben-David, QF Gan, T Golan-Lev, P Arora, O Yanuka, YS Oren, ... Cell stem cell 12 (2), 167-179, 2013 | 352 | 2013 |
Assessing the safety of stem cell therapeutics CEP Goldring, PA Duffy, N Benvenisty, PW Andrews, U Ben-David, ... Cell stem cell 8 (6), 618-628, 2011 | 295 | 2011 |
Large-scale analysis reveals acquisition of lineage-specific chromosomal aberrations in human adult stem cells U Ben-David, Y Mayshar, N Benvenisty Cell stem cell 9 (2), 97-102, 2011 | 274 | 2011 |
Cas9 activates the p53 pathway and selects for p53-inactivating mutations OM Enache, V Rendo, M Abdusamad, D Lam, D Davison, S Pal, ... Nature genetics 52 (7), 662-668, 2020 | 224 | 2020 |
Genomic evolution of cancer models: perils and opportunities U Ben-David, R Beroukhim, TR Golub Nature Reviews Cancer 19 (2), 97-109, 2019 | 211 | 2019 |
Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells U Ben-David, G Arad, U Weissbein, B Mandefro, A Maimon, T Golan-Lev, ... Nature communications 5 (1), 4825, 2014 | 182 | 2014 |
Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells U Ben-David, N Nudel, N Benvenisty Nature communications 4 (1), 1992, 2013 | 170 | 2013 |
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition Y Cohen-Sharir, JM McFarland, M Abdusamad, C Marquis, SV Bernhard, ... Nature 590 (7846), 486-491, 2021 | 168 | 2021 |
Genome maintenance in pluripotent stem cells U Weissbein, N Benvenisty, U Ben-David Journal of Cell Biology 204 (2), 153-163, 2014 | 159 | 2014 |
Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies JA Heslop, TG Hammond, I Santeramo, A Tort Piella, I Hopp, J Zhou, ... Stem cells translational medicine 4 (4), 389-400, 2015 | 136 | 2015 |
Landscape of genomic alterations in pituitary adenomas WL Bi, P Horowitz, NF Greenwald, M Abedalthagafi, PK Agarwalla, ... Clinical Cancer Research 23 (7), 1841-1851, 2017 | 125 | 2017 |
Frequent aneuploidy in primary human T cells after CRISPR–Cas9 cleavage AD Nahmad, E Reuveni, E Goldschmidt, T Tenne, M Liberman, ... Nature biotechnology 40 (12), 1807-1813, 2022 | 121 | 2022 |
Genomic instability in human pluripotent stem cells arises from replicative stress and chromosome condensation defects N Lamm, U Ben-David, T Golan-Lev, Z Storchová, N Benvenisty, B Kerem Cell stem cell 18 (2), 253-261, 2016 | 121 | 2016 |