| Unique toll-like receptor 4 activation by NAMPT/PBEF induces NFκB signaling and inflammatory lung injury SM Camp, E Ceco, CL Evenoski, SM Danilov, T Zhou, ET Chiang, ... Scientific reports 5 (1), 13135, 2015 | 154 | 2015 |
| Sphingosine-1–phosphate receptor–3 is a novel biomarker in acute lung injury X Sun, PA Singleton, E Letsiou, J Zhao, P Belvitch, S Sammani, ... American journal of respiratory cell and molecular biology 47 (5), 628-636, 2012 | 102 | 2012 |
| Pleiotropic effects of interleukin-6 in a “two-hit” murine model of acute respiratory distress syndrome JL Goldman, S Sammani, C Kempf, L Saadat, E Letsiou, T Wang, ... Pulmonary circulation 4 (2), 280-288, 2014 | 94 | 2014 |
| Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury AN Rizzo, S Sammani, AE Esquinca, JR Jacobson, JGN Garcia, E Letsiou, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015 | 87 | 2015 |
| Pathologic mechanical stress and endotoxin exposure increases lung endothelial microparticle shedding E Letsiou, S Sammani, W Zhang, T Zhou, H Quijada, L Moreno-Vinasco, ... American journal of respiratory cell and molecular biology 52 (2), 193-204, 2015 | 81 | 2015 |
| Differential and opposing effects of imatinib on LPS-and ventilator-induced lung injury E Letsiou, AN Rizzo, S Sammani, P Naureckas, JR Jacobson, JGN Garcia, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (3 …, 2015 | 71 | 2015 |
| Type 2 deiodinase and host responses of sepsis and acute lung injury SF Ma, L Xie, M Pino-Yanes, S Sammani, MS Wade, E Letsiou, J Siegler, ... American journal of respiratory cell and molecular biology 45 (6), 1203-1211, 2011 | 70 | 2011 |
| Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in murine models of inflammatory lung injury L Moreno-Vinasco, H Quijada, S Sammani, J Siegler, E Letsiou, R Deaton, ... American journal of respiratory cell and molecular biology 51 (2), 223-228, 2014 | 51 | 2014 |
| FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury L Wang, S Sammani, L Moreno-Vinasco, E Letsiou, T Wang, SM Camp, ... Critical care medicine 42 (3), e189-e199, 2014 | 51 | 2014 |
| Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA A Nerlich, M Mieth, E Letsiou, D Fatykhova, K Zscheppang, ... Scientific reports 8 (1), 182, 2018 | 49 | 2018 |
| Role of caveolin-1 expression in the pathogenesis of pulmonary edema in ventilator-induced lung injury NA Maniatis, M Kardara, D Hecimovich, E Letsiou, M Castellon, ... Pulmonary circulation 2 (4), 452-460, 2012 | 47 | 2012 |
| Inhaled activated protein C protects mice from ventilator-induced lung injury NA Maniatis, E Letsiou, SE Orfanos, M Kardara, I Dimopoulou, G Nakos, ... Critical Care 14, 1-14, 2010 | 42 | 2010 |
| Endothelial extracellular vesicles in pulmonary function and disease E Letsiou, N Bauer Current topics in membranes 82, 197-256, 2018 | 40 | 2018 |
| Parkin regulates lipopolysaccharide-induced proinflammatory responses in acute lung injury E Letsiou, S Sammani, H Wang, P Belvitch, SM Dudek Translational Research 181, 71-82, 2017 | 37 | 2017 |
| Lysozyme and bilirubin bind to ACE and regulate its conformation and shedding SM Danilov, H Lünsdorf, HT Akinbi, AB Nesterovitch, Y Epshtein, ... Scientific reports 6 (1), 34913, 2016 | 32 | 2016 |
| Neutralizing complement C5a protects mice with pneumococcal pulmonary sepsis H Müller-Redetzky, U Kellermann, SM Wienhold, B Gutbier, J Lienau, ... Anesthesiology 132 (4), 795-807, 2020 | 23 | 2020 |
| The ARP 2/3 complex mediates endothelial barrier function and recovery P Belvitch, ME Brown, BN Brinley, E Letsiou, AN Rizzo, JGN Garcia, ... Pulmonary Circulation 7 (1), 200-210, 2017 | 21 | 2017 |
| Neutrophil-derived extracellular vesicles activate platelets after pneumolysin exposure E Letsiou, LG Teixeira Alves, M Felten, TJ Mitchell, HC Müller-Redetzky, ... Cells 10 (12), 3581, 2021 | 20 | 2021 |
| Sphingosine kinase 1 regulates inflammation and contributes to acute lung injury in pneumococcal pneumonia via the sphingosine-1-phosphate receptor 2 B Gutbier, SM Schönrock, C Ehrler, R Haberberger, K Dietert, AD Gruber, ... Critical care medicine 46 (3), e258-e267, 2018 | 20 | 2018 |
| Mild stretch activates cPLA2 in alveolar type II epithelial cells independently through the MEK/ERK and PI3K pathways E Letsiou, EI Kitsiouli, G Nakos, ME Lekka Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2011 | 20 | 2011 |
