LRRC8A: C/E heteromeric channels are ubiquitous transporters of cGAMP LJ Lahey, RE Mardjuki, X Wen, GT Hess, C Ritchie, JA Carozza, ... Molecular cell 80 (4), 578-591. e5, 2020 | 144 | 2020 |
Mammalian interspecies substitution of immune modulatory alleles by genome editing SG Lillico, C Proudfoot, TJ King, W Tan, L Zhang, R Mardjuki, ... Scientific reports 6 (1), 21645, 2016 | 132 | 2016 |
Structure-aided development of small-molecule inhibitors of ENPP1, the extracellular phosphodiesterase of the immunotransmitter cGAMP JA Carozza, JA Brown, V Böhnert, D Fernandez, Y AlSaif, RE Mardjuki, ... Cell chemical biology 27 (11), 1347-1358. e5, 2020 | 88 | 2020 |
ENPP1’s regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling JA Carozza, AF Cordova, JA Brown, Y AlSaif, V Böhnert, X Cao, ... Proceedings of the National Academy of Sciences 119 (21), e2119189119, 2022 | 63 | 2022 |
Development of cGAMP-Luc, a sensitive and precise coupled enzyme assay to measure cGAMP in complex biological samples RE Mardjuki, JA Carozza, L Li Journal of Biological Chemistry 295 (15), 4881-4892, 2020 | 24 | 2020 |
The LRRC8A: C heteromeric channel is a cGAMP transporter and the dominant cGAMP importer in human vasculature cells LJ Lahey, X Wen, RE Mardjuki, V Böhnert, C Ritchie, JA Carozza, ... BioRxiv, 2020.02. 13.948273, 2020 | 12 | 2020 |
Murine M1 macrophages are among the direct responders to tumor-derived extracellular cGAMP and their human counterparts use SLC46A2 to import cGAMP AF Cordova, C Ritchie, V Böhnert, RE Mardjuki, L Li BioRxiv, 2020.04. 15.043299, 2020 | 7 | 2020 |
Mammalian interspecies substitution of immune modulatory alleles by genome editing. Sci Rep 6: 21645 SG Lillico, C Proudfoot, TJ King, W Tan, L Zhang, R Mardjuki, ... | 7 | 2016 |
Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint R Mardjuki, S Wang, J Carozza, B Zirak, V Subramanyam, G Abhiraman, ... Cell Reports 43 (5), 2024 | 6 | 2024 |
PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity W Wei, X Lyu, AL Markhard, S Fu, RE Mardjuki, PE Cavanagh, X Zeng, ... Nature 633 (8028), 182-188, 2024 | 3 | 2024 |
Identification of extracellular membrane protein ENPP3 as a major cGAMP hydrolase, cementing cGAMP's role as an immunotransmitter R Mardjuki, S Wang, J Carozza, G Abhiraman, X Lyu, L Li bioRxiv, 2024.01. 12.575449, 2024 | 2 | 2024 |
A PTER-dependent pathway of taurine metabolism linked to energy balance W Wei, X Lyu, AL Markhard, S Fu, RE Mardjuki, PE Cavanagh, X Zeng, ... bioRxiv, 2024 | 1 | 2024 |
Mapping the Therapeutic Checkpoints of the STING Pathway RE Mardjuki Stanford University, 2023 | | 2023 |