关注
Tao Hu
Tao Hu
Center for Drug Evaluation and Research, FDA
在 fda.hhs.gov 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mechanisms of drug resistance in colon cancer and its therapeutic strategies
T Hu, Z Li, CY Gao, CH Cho
World journal of gastroenterology 22 (30), 6876, 2016
3742016
Cigarette smoking and gastrointestinal diseases: the causal relationship and underlying molecular mechanisms
LF Li, RLY Chan, L Lu, J Shen, L Zhang, WKK Wu, L Wang, T Hu, MX Li, ...
International journal of molecular medicine 34 (2), 372-380, 2014
2592014
Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics
DJ Wagner, T Hu, J Wang
Pharmacological research 111, 237-246, 2016
1062016
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza
T Hu, KKW To, L Wang, L Zhang, L Lu, J Shen, RLY Chan, M Li, ...
Phytomedicine 21 (11), 1264-1272, 2014
1042014
Sensitivity of apoptosis-resistant colon cancer cells to tanshinones is mediated by autophagic cell death and p53-independent cytotoxicity
T Hu, L Wang, L Zhang, L Lu, J Shen, RLY Chan, M Li, WKK Wu, KKW To, ...
Phytomedicine 22 (5), 536-544, 2015
892015
Reversal of P-gp and BCRP-mediated MDR by tariquidar derivatives
XQ Li, L Wang, Y Lei, T Hu, FL Zhang, CH Cho, KKW To
European journal of medicinal chemistry 101, 560-572, 2015
702015
Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer
L Wang, T Hu, J Shen, L Zhang, RLY Chan, L Lu, M Li, CH Cho, WKK Wu
Phytomedicine 22 (12), 1079-1087, 2015
682015
Potent and selective inhibition of plasma membrane monoamine transporter by HIV protease inhibitors
H Duan, T Hu, RS Foti, Y Pan, PW Swaan, J Wang
Drug Metabolism and Disposition 43 (11), 1773-1780, 2015
612015
Serotonin transporter deficiency drives estrogen-dependent obesity and glucose intolerance
W Zha, HTB Ho, T Hu, MF Hebert, J Wang
Scientific Reports 7 (1), 1-14, 2017
582017
Chronic inflammation and colorectal cancer: the role of vascular endothelial growth factor
T Hu, L Fei Li, J Shen, L Zhang, C Hin Cho
Current pharmaceutical design 21 (21), 2960-2967, 2015
552015
Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes
X Zhou, Y Wang, T Hu, PMY Or, J Wong, YW Kwan, DCC Wan, PM Hoi, ...
Phytomedicine 20 (3-4), 367-374, 2013
552013
Cryptotanshinone induces ROS-dependent autophagy in multidrug-resistant colon cancer cells
Z Xu, H Jiang, Y Zhu, H Wang, J Jiang, L Chen, W Xu, T Hu, CH Cho
Chemico-biological interactions 273, 48-55, 2017
522017
Dihydrotanshinone induces p53-independent but ROS-dependent apoptosis in colon cancer cells
L Wang, JHK Yeung, T Hu, WY Lee, L Lu, L Zhang, J Shen, RLY Chan, ...
Life sciences 93 (8), 344-351, 2013
452013
Miltirone induced mitochondrial dysfunction and ROS-dependent apoptosis in colon cancer cells
L Wang, T Hu, J Shen, L Zhang, L Li, RLY Chan, M Li, WKK Wu, CH Cho
Life sciences 151, 224-234, 2016
432016
Effects of tanshinones from Salvia miltiorrhiza on CYP2C19 activity in human liver microsomes: enzyme kinetic and molecular docking studies
T Hu, X Zhou, L Wang, PMY Or, JHK Yeung, YW Kwan, CH Cho
Chemico-Biological Interactions 230, 1-8, 2015
272015
Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro
JY Ma, X Zhou, J Fu, T Hu, PMY Or, R Feng, CY He, WJ Chen, X Zhang, ...
Chemico-Biological Interactions 220, 33-40, 2014
182014
Metformin disrupts bile acid efflux by repressing bile salt export pump expression
B Garzel, T Hu, L Li, Y Lu, S Heyward, J Polli, L Zhang, SM Huang, ...
Pharmaceutical research 37, 1-10, 2020
172020
In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2, 3, 5-trimethoxy-xanthone purified from Halenia elliptica D. Don
R Feng, X Zhou, XS Tan, PMY Or, T Hu, J Fu, JY Ma, M Huang, CY He, ...
Chemico-biological interactions 210, 12-19, 2014
132014
Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies
CH Cho, T Hu
Academic Press, 2020
122020
Potential applications of tanshinones in gastrointestinal and hepatic diseases
T Hu, CH Cho
J Biomol Res Ther 2 (110), 2, 2013
122013
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