Mechanisms of drug resistance in colon cancer and its therapeutic strategies T Hu, Z Li, CY Gao, CH Cho World journal of gastroenterology 22 (30), 6876, 2016 | 374 | 2016 |
Cigarette smoking and gastrointestinal diseases: the causal relationship and underlying molecular mechanisms LF Li, RLY Chan, L Lu, J Shen, L Zhang, WKK Wu, L Wang, T Hu, MX Li, ... International journal of molecular medicine 34 (2), 372-380, 2014 | 259 | 2014 |
Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics DJ Wagner, T Hu, J Wang Pharmacological research 111, 237-246, 2016 | 106 | 2016 |
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza T Hu, KKW To, L Wang, L Zhang, L Lu, J Shen, RLY Chan, M Li, ... Phytomedicine 21 (11), 1264-1272, 2014 | 104 | 2014 |
Sensitivity of apoptosis-resistant colon cancer cells to tanshinones is mediated by autophagic cell death and p53-independent cytotoxicity T Hu, L Wang, L Zhang, L Lu, J Shen, RLY Chan, M Li, WKK Wu, KKW To, ... Phytomedicine 22 (5), 536-544, 2015 | 89 | 2015 |
Reversal of P-gp and BCRP-mediated MDR by tariquidar derivatives XQ Li, L Wang, Y Lei, T Hu, FL Zhang, CH Cho, KKW To European journal of medicinal chemistry 101, 560-572, 2015 | 70 | 2015 |
Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer L Wang, T Hu, J Shen, L Zhang, RLY Chan, L Lu, M Li, CH Cho, WKK Wu Phytomedicine 22 (12), 1079-1087, 2015 | 68 | 2015 |
Potent and selective inhibition of plasma membrane monoamine transporter by HIV protease inhibitors H Duan, T Hu, RS Foti, Y Pan, PW Swaan, J Wang Drug Metabolism and Disposition 43 (11), 1773-1780, 2015 | 61 | 2015 |
Serotonin transporter deficiency drives estrogen-dependent obesity and glucose intolerance W Zha, HTB Ho, T Hu, MF Hebert, J Wang Scientific Reports 7 (1), 1-14, 2017 | 58 | 2017 |
Chronic inflammation and colorectal cancer: the role of vascular endothelial growth factor T Hu, L Fei Li, J Shen, L Zhang, C Hin Cho Current pharmaceutical design 21 (21), 2960-2967, 2015 | 55 | 2015 |
Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes X Zhou, Y Wang, T Hu, PMY Or, J Wong, YW Kwan, DCC Wan, PM Hoi, ... Phytomedicine 20 (3-4), 367-374, 2013 | 55 | 2013 |
Cryptotanshinone induces ROS-dependent autophagy in multidrug-resistant colon cancer cells Z Xu, H Jiang, Y Zhu, H Wang, J Jiang, L Chen, W Xu, T Hu, CH Cho Chemico-biological interactions 273, 48-55, 2017 | 52 | 2017 |
Dihydrotanshinone induces p53-independent but ROS-dependent apoptosis in colon cancer cells L Wang, JHK Yeung, T Hu, WY Lee, L Lu, L Zhang, J Shen, RLY Chan, ... Life sciences 93 (8), 344-351, 2013 | 45 | 2013 |
Miltirone induced mitochondrial dysfunction and ROS-dependent apoptosis in colon cancer cells L Wang, T Hu, J Shen, L Zhang, L Li, RLY Chan, M Li, WKK Wu, CH Cho Life sciences 151, 224-234, 2016 | 43 | 2016 |
Effects of tanshinones from Salvia miltiorrhiza on CYP2C19 activity in human liver microsomes: enzyme kinetic and molecular docking studies T Hu, X Zhou, L Wang, PMY Or, JHK Yeung, YW Kwan, CH Cho Chemico-Biological Interactions 230, 1-8, 2015 | 27 | 2015 |
Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro JY Ma, X Zhou, J Fu, T Hu, PMY Or, R Feng, CY He, WJ Chen, X Zhang, ... Chemico-Biological Interactions 220, 33-40, 2014 | 18 | 2014 |
Metformin disrupts bile acid efflux by repressing bile salt export pump expression B Garzel, T Hu, L Li, Y Lu, S Heyward, J Polli, L Zhang, SM Huang, ... Pharmaceutical research 37, 1-10, 2020 | 17 | 2020 |
In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2, 3, 5-trimethoxy-xanthone purified from Halenia elliptica D. Don R Feng, X Zhou, XS Tan, PMY Or, T Hu, J Fu, JY Ma, M Huang, CY He, ... Chemico-biological interactions 210, 12-19, 2014 | 13 | 2014 |
Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies CH Cho, T Hu Academic Press, 2020 | 12 | 2020 |
Potential applications of tanshinones in gastrointestinal and hepatic diseases T Hu, CH Cho J Biomol Res Ther 2 (110), 2, 2013 | 12 | 2013 |