Efficient bacterial inactivation by transition metal catalyzed auto-oxidation of sulfite L Chen, M Tang, C Chen, M Chen, K Luo, J Xu, D Zhou, F Wu Environmental Science & Technology 51 (21), 12663-12671, 2017 | 138 | 2017 |
High potency of a bivalent human VH domain in SARS-CoV-2 animal models W Li, A Schäfer, SS Kulkarni, X Liu, DR Martinez, C Chen, Z Sun, SR Leist, ... Cell 183 (2), 429-441. e16, 2020 | 124 | 2020 |
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection W Li, C Chen, A Drelich, DR Martinez, LE Gralinski, Z Sun, A Schäfer, ... Proceedings of the National Academy of Sciences 117 (47), 29832-29838, 2020 | 90 | 2020 |
Critical role of matrix metalloproteinase 14 in adipose tissue remodeling during obesity X Li, Y Zhao, C Chen, L Yang, H Lee, Z Wang, N Zhang, MG Kolonin, Z An, ... Molecular and cellular biology 40 (8), e00564-19, 2020 | 79 | 2020 |
Non-lytic M13 phage-based highly sensitive impedimetric cytosensor for detection of coliforms M Sedki, X Chen, C Chen, X Ge, A Mulchandani Biosensors and Bioelectronics 148, 111794, 2020 | 71 | 2020 |
Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold Z Sun, C Chen, W Li, DR Martinez, A Drelich, DS Baek, X Liu, JW Mellors, ... MAbs 12 (1), 1778435, 2020 | 63 | 2020 |
Functional selection of protease inhibitory antibodies T Lopez, Z Mustafa, C Chen, KB Lee, A Ramirez, C Benitez, X Luo, RR Ji, ... Proceedings of the National Academy of Sciences 116 (33), 16314-16319, 2019 | 39 | 2019 |
Enhanced elicitation of potent neutralizing antibodies by the SARS-CoV-2 spike receptor binding domain Fc fusion protein in mice X Liu, A Drelich, W Li, C Chen, Z Sun, M Shi, C Adams, JW Mellors, ... Vaccine 38 (46), 7205-7212, 2020 | 32 | 2020 |
Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody W Li, A Drelich, DR Martinez, L Gralinski, C Chen, Z Sun, X Liu, D Zhelev, ... BioRxiv 93088, 2020 | 25 | 2020 |
Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells S Chen, J Qiu, C Chen, C Liu, Y Liu, L An, J Jia, J Tang, L Wu, H Hang Protein & cell 3 (6), 460-469, 2012 | 25 | 2012 |
Coupling recombinase‐mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells C Chen, N Li, Y Zhao, H Hang Biotechnology and bioengineering 113 (1), 39-51, 2016 | 18 | 2016 |
Host-derived CD70 suppresses murine graft-versus-host disease by limiting donor T cell expansion and effector function ND Leigh, RE O’Neill, W Du, C Chen, J Qiu, JD Ashwell, PL McCarthy, ... The Journal of Immunology 199 (1), 336-347, 2017 | 17 | 2017 |
Rapid selection of a human monoclonal antibody that potently neutralizes SARS-CoV-2 in two animal models W Li, A Drelich, DR Martinez, L Gralinski, C Chen, Z Sun, A Schäfer, ... BioRxiv, 2020.05. 13.093088, 2020 | 13 | 2020 |
Use of a novel camelid-inspired human antibody demonstrates the importance of MMP-14 to cancer stem cell function in the metastatic process KHE Chen, C Chen, T Lopez, KC Radecki, K Bustamante, MY Lorenson, ... Oncotarget 9 (50), 29431, 2018 | 13 | 2018 |
Serine protease inhibitor 6 protects alloreactive T cells from Granzyme B-mediated mitochondrial damage without affecting graft-versus-tumor effect W Du, H Mohammadpour, RE O'Neill, S Kumar, C Chen, M Qiu, L Mei, ... Oncoimmunology 7 (3), e1397247, 2018 | 12 | 2018 |
Neutralization of European, South African, and United States SARS-CoV-2 mutants by a human antibody and antibody domains Z Sun, A Kim, MD Sobolewski, N Enick, C Chen, C Adams, JL Jacobs, ... BioRxiv, 2021.03. 22.436481, 2021 | 11 | 2021 |
Effective killing of cells expressing CD276 (B7-H3) by a bispecific T cell engager based on a new fully human antibody X Liu, D Zhelev, C Adams, C Chen, JW Mellors, DS Dimitrov Translational Oncology 14 (12), 101232, 2021 | 8 | 2021 |
Epitope‐specific affinity maturation improved stability of potent protease inhibitory antibodies T Lopez, C Chuan, A Ramirez, KHE Chen, MY Lorenson, C Benitez, ... Biotechnology and bioengineering 115 (11), 2673-2682, 2018 | 8 | 2018 |
Molecules that bind to SARS-CoV-2 DS Dimitrov, C Chen, DV Jelev, JW Mellors, W Li, Z Sun US Patent 10,822,379, 2020 | 7 | 2020 |
Protocol for constructing large size human antibody heavy chain variable domain (VH) library and selection of SARS-CoV-2 neutralizing antibody domains C Chen, Z Sun, X Liu, W Li, DS Dimitrov STAR protocols 2 (3), 100617, 2021 | 5 | 2021 |