| The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches SL Cheong, S Federico, G Venkatesan, AL Mandel, YM Shao, S Moro, ... Medicinal Research Reviews 33 (2), 235-335, 2013 | 57 | 2013 |
| The current status of pharmacotherapy for the treatment of Parkinson’s disease: Transition from single-target to multitarget therapy SL Cheong, S Federico, G Spalluto, KN Klotz, G Pastorin Drug discovery today 24 (9), 1769-1783, 2019 | 52 | 2019 |
| The Significance of 2-Furyl Ring Substitution with a 2-(para-substituted) Aryl Group in a New Series of Pyrazolo-triazolo-pyrimidines as Potent and Highly Selective hA3 … SL Cheong, A Dolzhenko, S Kachler, S Paoletta, S Federico, B Cacciari, ... Journal of Medicinal Chemistry 53 (8), 3361-3375, 2010 | 44 | 2010 |
| Current progress in antimalarial pharmacotherapy and multi-target drug discovery NS Tibon, CH Ng, SL Cheong European journal of medicinal chemistry 188, 111983, 2020 | 43 | 2020 |
| Synthesis and Biological Evaluation of a New Series of 1,2,4-Triazolo[1,5-a]-1,3,5-triazines as Human A2A Adenosine Receptor Antagonists with Improved Water … S Federico, S Paoletta, SL Cheong, G Pastorin, B Cacciari, S Stragliotto, ... Journal of medicinal chemistry 54 (3), 877-889, 2011 | 41 | 2011 |
| Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson's disease treatment YM Shao, X Ma, P Paira, A Tan, DR Herr, KL Lim, CH Ng, G Venkatesan, ... PloS one 13 (1), e0188212, 2018 | 34 | 2018 |
| Organoruthenium Antagonists of Human A3 Adenosine Receptors P Paira, MJ Chow, G Venkatesan, VK Kosaraju, SL Cheong, KN Klotz, ... Chemistry–A European Journal 19 (25), 8321-8330, 2013 | 18 | 2013 |
| Pyrazolo derivatives as potent adenosine receptor antagonists: an overview on the structure-activity relationships SL Cheong, G Venkatesan, P Paira, R Jothibasu, AL Mandel, S Federico, ... International Journal of Medicinal Chemistry 2011, 2011 | 17 | 2011 |
| Discovery of simplified N2-substituted pyrazolo [3, 4-d] pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations … G Venkatesan, P Paira, SL Cheong, K Vamsikrishna, S Federico, KN Klotz, ... Bioorganic & Medicinal Chemistry 22 (5), 1751-1765, 2014 | 16 | 2014 |
| Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists SL Cheong, S Federico, G Venkatesan, P Paira, YM Shao, G Spalluto, ... Bioorganic & medicinal chemistry letters 21 (10), 2898-2905, 2011 | 15 | 2011 |
| Design, Synthesis and Characterisation of Novel Phenothiazine‐Based Triazolopyridine Derivatives: Evaluation of Anti‐Breast Cancer Activity on Human Breast Carcinoma T Sachdeva, ML Low, CW Mai, SL Cheong, YK Liew, MD Milton ChemistrySelect 4 (43), 12701-12707, 2019 | 14 | 2019 |
| Does the combination of optimal substitutions at the C2-, N5-and N8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 … SL Cheong, AV Dolzhenko, S Paoletta, EPR Lee, S Kachler, S Federico, ... Bioorganic & medicinal chemistry 19 (20), 6120-6134, 2011 | 12 | 2011 |
| A facile and novel synthesis of N2-, C6-substituted pyrazolo [3, 4-d] pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists G Venkatesan, P Paira, SL Cheong, S Federico, KN Klotz, G Spalluto, ... European Journal of Medicinal Chemistry 92, 784-798, 2015 | 9 | 2015 |
| Current Pharmacotherapy and Multi-Target Approaches for Alzheimer’s Disease SL Cheong, JK Tiew, YH Fong, HW Leong, YM Chan, ZL Chan, ... Pharmaceuticals 15 (12), 1560, 2022 | 6 | 2022 |
| Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases YC Chow, HC Yam, B Gunasekaran, WY Lai, WY Wo, T Agarwal, YY Ong, ... Frontiers in Cellular and Infection Microbiology 12, 1456, 2022 | 4 | 2022 |
| Inhibition of Porphyromonas gingivalis peptidyl arginine deiminase, a virulence factor, by antioxidant-rich Cratoxylum cochinchinense: In vitro and in silico evaluation SA Tan, HC Yam, SL Cheong, YC Chow, CY Bok, JM Ho, PY Lee, ... Saudi Journal of Biological Sciences 29 (4), 2573-2581, 2022 | 3 | 2022 |
| Pharmacological relationships and ligand discovery of G protein-coupled receptors revealed by simultaneous ligand and receptor clustering C Zhang, YM Shao, X Ma, SL Cheong, C Qin, L Tao, P Zhang, S Chen, ... Journal of Molecular Graphics and Modelling 76, 136-142, 2017 | 1 | 2017 |
| Novel Cu (II) Schiff Base Complex Combination with Polymyxin B/Phenylalanine-Arginine β-Naphthylamide Against Various Bacterial Strains WK Gan, HS Liew, LJW Pua, XY Ng, KW Fong, SL Cheong, YK Liew, ... International Journal of Peptide Research and Therapeutics 28 (2), 60, 2022 | | 2022 |
| Design, synthesis and evaluation of new indolylpyrimidylpiperazines for gastrointestinal cancer therapy A Tan, MV Babak, G Venkatesan, C Lim, KN Klotz, DR Herr, SL Cheong, ... Molecules 24 (20), 3661, 2019 | | 2019 |
| A3 adenosine receptor ligands in the treatment of inflammation and cancer SL Cheong, S Federico, A Tan Bon Wu, G Spalluto, G Pastorin PHARMACOLOGY-RESEARCH, SAFETY TESTING AND REGULATION, 1-72, 2016 | | 2016 |
