Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway CL Evavold, I Hafner-Bratkovič, P Devant, JM D’Andrea, EM Ngwa, ... Cell 184 (17), 4495-4511. e19, 2021 | 269 | 2021 |
Gasdermin D pore-forming activity is redox-sensitive P Devant, E Boršić, EM Ngwa, H Xiao, ET Chouchani, JR Thiagarajah, ... Cell reports 42 (1), 2023 | 59 | 2023 |
Molecular mechanisms of gasdermin D pore-forming activity P Devant, JC Kagan Nature Immunology 24 (7), 1064-1075, 2023 | 55 | 2023 |
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death JP Borges, RSR Sætra, A Volchuk, M Bugge, P Devant, B Sporsheim, ... Elife 11, e78609, 2022 | 40 | 2022 |
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis A Balasubramanian, AY Hsu, L Ghimire, M Tahir, P Devant, P Fontana, ... Science immunology 9 (94), eadn1452, 2024 | 34 | 2024 |
Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia S Sekulovski, P Devant, S Panizza, T Gogakos, A Pitiriciu, K Heitmeier, ... Nature communications 12 (1), 5610, 2021 | 34 | 2021 |
Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1β–converting enzyme P Devant, A Cao, JC Kagan Science immunology 6 (62), eabh3567, 2021 | 27 | 2021 |
ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation G Du, LB Healy, L David, C Walker, P Fontana, Y Dong, P Devant, ... BioRxiv, 2023.03. 07.531538, 2023 | 25 | 2023 |
Structural insights into cytokine cleavage by inflammatory caspase-4 P Devant, Y Dong, J Mintseris, W Ma, SP Gygi, H Wu, JC Kagan Nature 624 (7991), 451-459, 2023 | 15 | 2023 |
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D G Du, LB Healy, L David, C Walker, TJ El-Baba, CA Lutomski, B Goh, ... Nature, 1-3, 2024 | 11 | 2024 |
The pore-forming protein gasdermin D is a cellular redox sensor P Devant, E Boršić, EM Ngwa, JR Thiagarajah, I Hafner-Bratkovič, ... bioRxiv, 2022.03. 11.484021, 2022 | 5 | 2022 |
Engineering an antibody V gene-selective vaccine L Ronsard, AS Yousif, J Peabody, V Okonkwo, P Devant, AT Mogus, ... Frontiers in immunology 12, 730471, 2021 | 5 | 2021 |
Evolution-inspired dissection of caspase activities enables the redesign of caspase-4 into an LPS sensing interleukin-1 converting enzyme P Devant, A Cao, JC Kagan bioRxiv, 2020.12. 07.413732, 2020 | 3 | 2020 |
Structural transitions enable interleukin-18 maturation and signaling Y Dong, JP Bonin, P Devant, Z Liang, AIM Sever, J Mintseris, JM Aramini, ... Immunity, 2024 | 2 | 2024 |
Protocol to purify recombinant inflammatory caspases and assess their catalytic activity in vitro P Devant, JC Kagan STAR protocols 3 (4), 101848, 2022 | 2 | 2022 |
Correction of age-associated defects in dendritic cells enables CD4+ T cells to eradicate tumors D Zhivaki, SN Kennedy, J Park, F Boriello, P Devant, A Cao, KM Bahleda, ... Cell, 2024 | | 2024 |
Publisher Correction: Structural insights into cytokine cleavage by inflammatory caspase-4 P Devant, Y Dong, J Mintseris, W Ma, SP Gygi, H Wu, JC Kagan Nature 625 (7995), E17-E17, 2024 | | 2024 |
Regulating the unregulated: what host factors are required for GSDMD pore formation? CL Evavold, I Hafner-Bratkovic, P Devant, JC Kagan The Journal of Immunology 206 (1_Supplement), 111.06-111.06, 2021 | | 2021 |
ROS-Dependent Palmitoylation Activates Pore Formation by Cleaved and Intact GSDMD G Du, LB Healy, L David, C Walker, TJ El-Baba, CA Lutomski, B Goh, X Pi, ... | | |