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Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers C Mathis, C Poussin, D Weisensee, S Gebel, A Hengstermann, A Sewer, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 304 (7 …, 2013 | 162 | 2013 |
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Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by … B Phillips, B Titz, U Kogel, D Sharma, P Leroy, Y Xiang, G Vuillaume, ... Food and Chemical Toxicology 109, 315-332, 2017 | 134 | 2017 |
Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge AL Tarca, M Lauria, M Unger, E Bilal, S Boue, K Kumar Dey, J Hoeng, ... Bioinformatics 29 (22), 2892-2899, 2013 | 133 | 2013 |
Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models F Martin, A Sewer, M Talikka, Y Xiang, J Hoeng, MC Peitsch BMC bioinformatics 15, 1-24, 2014 | 114 | 2014 |
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with … ET Wong, U Kogel, E Veljkovic, F Martin, Y Xiang, S Boue, G Vuillaume, ... Regulatory Toxicology and Pharmacology 81, S59-S81, 2016 | 94 | 2016 |
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Generalized Simulated Annealing Studies on Structures and Properties of Nin (n = 2−55) Clusters Y Xiang, DY Sun, XG Gong The Journal of Physical Chemistry A 104 (12), 2746-2751, 2000 | 83 | 2000 |
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared … U Kogel, WK Schlage, F Martin, Y Xiang, S Ansari, P Leroy, ... Food and chemical toxicology 68, 204-217, 2014 | 81 | 2014 |
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3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product AR Iskandar, C Mathis, F Martin, P Leroy, A Sewer, S Majeed, D Kuehn, ... ALTEX-Alternatives to animal experimentation 34 (1), 23-48, 2017 | 69 | 2017 |
A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human … AR Iskandar, C Mathis, WK Schlage, S Frentzel, P Leroy, Y Xiang, ... Toxicology in vitro 39, 29-51, 2017 | 65 | 2017 |
Impact assessment of cigarette smoke exposure on organotypic bronchial epithelial tissue cultures: a comparison of mono-culture and coculture model containing fibroblasts AR Iskandar, Y Xiang, S Frentzel, M Talikka, P Leroy, D Kuehn, E Guedj, ... Toxicological Sciences 147 (1), 207-221, 2015 | 62 | 2015 |
In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue … WK Schlage, AR Iskandar, R Kostadinova, Y Xiang, A Sewer, S Majeed, ... Toxicology mechanisms and methods 24 (7), 470-487, 2014 | 61 | 2014 |
Evaluation of the Tobacco Heating System 2.2 (THS2. 2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2. 2 aerosol causes reduced … A Sewer, U Kogel, M Talikka, ET Wong, F Martin, Y Xiang, E Guedj, ... Regulatory toxicology and pharmacology 81, S82-S92, 2016 | 55 | 2016 |
A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke J Szostak, ET Wong, B Titz, T Lee, SK Wong, T Low, KM Lee, J Zhang, ... American Journal of Physiology-Heart and Circulatory Physiology 318 (3 …, 2020 | 44 | 2020 |
Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells U Kogel, IG Suarez, Y Xiang, E Dossin, PA Guy, C Mathis, D Marescotti, ... Toxicology in Vitro 29 (8), 2102-2115, 2015 | 43 | 2015 |
The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure M Talikka, R Kostadinova, Y Xiang, C Mathis, A Sewer, S Majeed, ... International Journal of Toxicology 33 (6), 506-517, 2014 | 42 | 2014 |