Use of precision cut lung slices as a translational model for the study of lung biology G Liu, C Betts, DM Cunoosamy, PM Åberg, JJ Hornberg, KB Sivars, ... Respiratory research 20, 1-14, 2019 | 193 | 2019 |
The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation FR Svedberg, SL Brown, MZ Krauss, L Campbell, C Sharpe, M Clausen, ... Nature immunology 20 (5), 571-580, 2019 | 174 | 2019 |
Role of B cell–activating factor in chronic obstructive pulmonary disease LJM Seys, FM Verhamme, A Schinwald, H Hammad, DM Cunoosamy, ... American journal of respiratory and critical care medicine 192 (6), 706-718, 2015 | 117 | 2015 |
Role of CXCL13 in Cigarette Smoke–induced Lymphoid Follicle Formation and Chronic Obstructive Pulmonary Disease KR Bracke, FM Verhamme, LJM Seys, C Bantsimba-Malanda, ... American journal of respiratory and critical care medicine 188 (3), 343-355, 2013 | 113 | 2013 |
Dynamics of IFN-β responses during respiratory viral infection. Insights for therapeutic strategies A Watson, CM Spalluto, C McCrae, D Cellura, H Burke, D Cunoosamy, ... American journal of respiratory and critical care medicine 201 (1), 83-94, 2020 | 65 | 2020 |
The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial NR Patel, DM Cunoosamy, M Fagerås, Z Taib, S Asimus, ... International journal of chronic obstructive pulmonary disease, 1009-1019, 2018 | 47 | 2018 |
Effects of peptidase inhibition on angiotensin receptor agonist and antagonist potency in rabbit isolated thoracic aorta MJ Robertson, MP Cunoosamy, KL Clark British journal of pharmacology 106 (1), 166-172, 1992 | 47 | 1992 |
Design, synthesis, and biological evaluation of MEK PROTACs S Vollmer, D Cunoosamy, H Lv, H Feng, X Li, Z Nan, W Yang, MWD Perry Journal of Medicinal Chemistry 63 (1), 157-162, 2019 | 46 | 2019 |
Human lung conventional dendritic cells orchestrate lymphoid neogenesis during chronic obstructive pulmonary disease T Naessens, Y Morias, E Hamrud, U Gehrmann, R Budida, J Mattsson, ... American journal of respiratory and critical care medicine 202 (4), 535-548, 2020 | 41 | 2020 |
Design of a chemical probe for the bromodomain and plant homeodomain finger-containing (BRPF) family of proteins N Igoe, ED Bayle, C Tallant, O Fedorov, JC Meier, P Savitsky, C Rogers, ... Journal of medicinal chemistry 60 (16), 6998-7011, 2017 | 38 | 2017 |
A disintegrin and metalloproteinase domain-8: a novel protective proteinase in chronic obstructive pulmonary disease F Polverino, J Rojas-Quintero, X Wang, H Petersen, L Zhang, X Gai, ... American journal of respiratory and critical care medicine 198 (10), 1254-1267, 2018 | 36 | 2018 |
A disintegrin and metalloproteinase domain-9: a novel proteinase culprit with multifarious contributions to chronic obstructive pulmonary disease X Wang, F Polverino, J Rojas-Quintero, D Zhang, J Sánchez, I Yambayev, ... American Journal of Respiratory and Critical Care Medicine 198 (12), 1500-1518, 2018 | 31 | 2018 |
Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA) E Khaleva, A Rattu, C Brightling, A Bush, A Bossios, A Bourdin, KF Chung, ... European Respiratory Journal 61 (4), 2023 | 29 | 2023 |
Differential anti-inflammatory effects of budesonide and a p38 MAPK inhibitor AZD7624 on COPD pulmonary cells A Higham, P Karur, N Jackson, DM Cunoosamy, P Jansson, D Singh International Journal of Chronic Obstructive Pulmonary Disease, 1279-1288, 2018 | 23 | 2018 |
Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus J Jubrail, K Africano‐Gomez, F Herit, A Mularski, P Bourdoncle, L Oberg, ... EMBO reports 21 (1), e47963, 2020 | 21 | 2020 |
MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling E Baturcam, S Vollmer, H Schlüter, RA Maciewicz, N Kurian, O Vaarala, ... Cell Communication and Signaling 17, 1-19, 2019 | 16 | 2019 |
Dual role for a MEK inhibitor as a modulator of inflammation and host defense mechanisms with potential therapeutic application in COPD N Kurian, TS Cohen, L Öberg, E De Zan, G Skogberg, S Vollmer, ... International Journal of Chronic Obstructive Pulmonary Disease, 2611-2624, 2019 | 14 | 2019 |
Dupilumab efficacy and biomarkers in chronic rhinosinusitis with nasal polyps: association between dupilumab treatment effect on nasal polyp score and biomarkers of type 2 … C Bachert, J Corren, SE Lee, H Zhang, S Harel, D Cunoosamy, AH Khan, ... International Forum of Allergy & Rhinology 12 (9), 1191-1195, 2022 | 10 | 2022 |
HRV16 impairs macrophages cytokine response to a secondary bacterial trigger J Jubrail, K Africano-Gomez, F Herit, E Baturcam, G Mayer, ... Frontiers in Immunology 9, 2908, 2018 | 10 | 2018 |
AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic Exposure R Pehrson, T Hegelund-Myrbäck, D Cunoosamy, S Asimus, P Jansson, ... Journal of Pharmacology and Experimental Therapeutics 365 (3), 567-572, 2018 | 6 | 2018 |