Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response P Jiang, S Gu, D Pan, J Fu, A Sahu, X Hu, Z Li, N Traugh, X Bu, B Li, J Liu, ... Nature medicine 24 (10), 1550-1558, 2018 | 3231 | 2018 |
Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma CD Carey, D Gusenleitner, M Lipschitz, MGM Roemer, EC Stack, E Gjini, ... Blood 130 (22), 2420-2430, 2017 | 309 | 2017 |
Reconstruction of enhancer–target networks in 935 samples of human primary cells, tissues and cell lines Q Cao, C Anyansi, X Hu, L Xu, L Xiong, W Tang, MTS Mok, C Cheng, ... Nature Genetics 201, 7, 2017 | 214 | 2017 |
TRUST4: immune repertoire reconstruction from bulk and single-cell RNA-seq data L Song, D Cohen, Z Ouyang, Y Cao, X Hu, XS Liu Nature Methods 18 (6), 627-630, 2021 | 158 | 2021 |
Mass cytometry of Hodgkin lymphoma reveals a CD4+ regulatory T-cell–rich and exhausted T-effector microenvironment FZ Cader, RCJ Schackmann, X Hu, K Wienand, R Redd, B Chapuy, ... Blood, The Journal of the American Society of Hematology 132 (8), 825-836, 2018 | 152 | 2018 |
Landscape of B cell immunity and related immune evasion in human cancers X Hu, J Zhang, J Wang, J Fu, T Li, X Zheng, B Wang, S Gu, P Jiang, J Fan, ... Nature genetics 51 (3), 560-567, 2019 | 129 | 2019 |
A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma FZ Cader, X Hu, WL Goh, K Wienand, J Ouyang, E Mandato, R Redd, ... Nature Medicine 26 (9), 1468-1479, 2020 | 112 | 2020 |
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells Y Xue, H Qian, J Hu, B Zhou, Y Zhou, X Hu, A Karakhanyan, Z Pang, ... Nature neuroscience 19 (6), 807-815, 2016 | 102 | 2016 |
Improved prediction of RNA secondary structure by integrating the free energy model with restraints derived from experimental probing data Y Wu, B Shi, X Ding, T Liu, X Hu, KY Yip, ZR Yang, DH Mathews, ZJ Lu Nucleic acids research 43 (15), 7247-7259, 2015 | 89 | 2015 |
Machine Learning Competition in Immunology–Prediction of HLA class I molecules GL Zhang, HR Ansari, P Bradley, GC Cawley, T Hertz, X Hu, N Jojic, ... Journal of Immunological Methods: In press (Impact factor: 2.340), 2011 | 67* | 2011 |
Immune receptor repertoires in pediatric and adult acute myeloid leukemia J Zhang, X Hu, J Wang, AD Sahu, D Cohen, L Song, Z Ouyang, J Fan, ... Genome medicine 11, 1-11, 2019 | 46 | 2019 |
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes J Chen, Z Cai, M Bai, X Yu, C Zhang, C Cao, X Hu, L Wang, R Su, ... Cell Research 28 (10), 981-995, 2018 | 41 | 2018 |
Predicting essential proteins by integrating orthology, gene expressions, and PPI networks X Zhang, W Xiao, X Hu PloS one 13 (4), e0195410, 2018 | 31 | 2018 |
A Bayesian regression approach to the prediction of MHC-II binding affinity W Zhang, J Liu, YQ Niu, L Wang, X Hu Computer methods and programs in biomedicine 92 (1), 1-7, 2008 | 26 | 2008 |
Identification of specificity determining residues in peptide recognition domains using an information theoretic approach applied to large-scale binding maps K Yip, L Utz, S Sitwell, X Hu, S Sidhu, B Turk, M Gerstein, P Kim BMC biology 9 (1), 53, 2011 | 24 | 2011 |
MetaMHC: a meta approach to predict peptides binding to MHC molecules X Hu, W Zhou, K Udaka, H Mamitsuka, S Zhu Nucleic Acids Research 38 (suppl 2), W474-W479, 2010 | 20 | 2010 |
Clonal tracing reveals diverse patterns of response to immune checkpoint blockade SS Gu, X Wang, X Hu, P Jiang, Z Li, N Traugh, X Bu, Q Tang, C Wang, ... Genome Biology 21 (1), 1-28, 2020 | 17 | 2020 |
A common set of distinct features that characterize noncoding RNAs across multiple species L Hu, C Di, M Kai, YCT Yang, Y Li, Y Qiu, X Hu, KY Yip, MQ Zhang, ZJ Lu Nucleic acids research 43 (1), 104-114, 2015 | 17 | 2015 |
Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments F Nannini, L Senicar, F Parekh, KJ Kong, A Kinna, R Bughda, ... MAbs 13 (1), 1864084, 2021 | 16 | 2021 |
Ensemble approaches for improving HLA Class I-peptide binding prediction X Hu, H Mamitsuka, S Zhu Journal of Immunological Methods, 2010 | 15 | 2010 |