| Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia R Lapalombella, Q Sun, K Williams, L Tangeman, S Jha, Y Zhong, ... Blood, The Journal of the American Society of Hematology 120 (23), 4621-4634, 2012 | 381 | 2012 |
| Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1 Q Sun, YP Carrasco, Y Hu, X Guo, H Mirzaei, J MacMillan, YM Chook Proceedings of the National Academy of Sciences 110 (4), 1303-1308, 2013 | 258 | 2013 |
| Structural basis for the inhibition mechanism of human cystathionine γ-lyase, an enzyme responsible for the production of H2S Q Sun, R Collins, S Huang, L Holmberg-Schiavone, GS Anand, CH Tan, ... Journal of Biological Chemistry 284 (5), 3076-3085, 2009 | 230 | 2009 |
| Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells J Etchin, Q Sun, A Kentsis, A Farmer, ZC Zhang, T Sanda, MR Mansour, ... Leukemia 27 (1), 66-74, 2013 | 209 | 2013 |
| Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies ZA Hing, HYJ Fung, P Ranganathan, S Mitchell, D El-Gamal, JA Woyach, ... Leukemia 30 (12), 2364-2372, 2016 | 147 | 2016 |
| Inhibiting cancer cell hallmark features through nuclear export inhibition Q Sun, X Chen, Q Zhou, E Burstein, S Yang, D Jia Signal transduction and targeted therapy 1 (1), 1-10, 2016 | 133 | 2016 |
| Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination JD Haines, O Herbin, B De La Hera, OG Vidaurre, GA Moy, Q Sun, ... Nature neuroscience 18 (4), 511-520, 2015 | 100 | 2015 |
| Structural basis for a novel intrapeptidyl H‐bond and reverse binding of c‐Cbl‐TKB domain substrates C Ng, RA Jackson, JP Buschdorf, Q Sun, GR Guy, J Sivaraman The EMBO journal 27 (5), 804-816, 2008 | 83 | 2008 |
| Mechanism of cargo recognition by retromer-linked SNX-BAR proteins X Yong, L Zhao, W Deng, H Sun, X Zhou, L Mao, W Hu, X Shen, Q Sun, ... PLoS biology 18 (3), e3000631, 2020 | 75 | 2020 |
| Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E L Volpon, B Culjkovic-Kraljacic, MJ Osborne, A Ramteke, Q Sun, ... Proceedings of the National Academy of Sciences 113 (19), 5263-5268, 2016 | 66 | 2016 |
| Mechanism of inhibition of retromer transport by the bacterial effector RidL J Yao, F Yang, X Sun, S Wang, N Gan, Q Liu, D Liu, X Zhang, D Niu, ... Proceedings of the National Academy of Sciences 115 (7), E1446-E1454, 2018 | 60 | 2018 |
| Structural and functional insights into sorting nexin 5/6 interaction with bacterial effector IncE Q Sun, X Yong, X Sun, F Yang, Z Dai, Y Gong, L Zhou, X Zhang, D Niu, ... Signal transduction and targeted therapy 2 (1), 1-7, 2017 | 51 | 2017 |
| SNX27-FERM-SNX1 complex structure rationalizes divergent trafficking pathways by SNX17 and SNX27 X Yong, L Zhao, W Hu, Q Sun, H Ham, Z Liu, J Ren, Z Zhang, Y Zhou, ... Proceedings of the National Academy of Sciences 118 (36), e2105510118, 2021 | 46 | 2021 |
| Cytoplasmic SHMT2 drives the progression and metastasis of colorectal cancer by inhibiting β-catenin degradation C Liu, L Wang, X Liu, Y Tan, L Tao, Y Xiao, P Deng, H Wang, Q Deng, ... Theranostics 11 (6), 2966, 2021 | 46 | 2021 |
| Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia JS Walker, ZA Hing, B Harrington, J Baumhardt, HG Ozer, A Lehman, ... Journal of hematology & oncology 14, 1-21, 2021 | 45 | 2021 |
| Nuclear transport proteins: Structure, function, and disease relevance Y Yang, L Guo, L Chen, B Gong, D Jia, Q Sun Signal Transduction and Targeted Therapy 8 (1), 425, 2023 | 41 | 2023 |
| Phosphorylation of SNX27 by MAPK11/14 links cellular stress–signaling pathways with endocytic recycling L Mao, C Liao, J Qin, Y Gong, Y Zhou, S Li, Z Liu, H Deng, W Deng, Q Sun, ... Journal of Cell Biology 220 (4), 2021 | 35 | 2021 |
| Structural and mechanistic insights into secretagogin-mediated exocytosis J Qin, Q Liu, Z Liu, YZ Pan, L Sifuentes-Dominguez, KP Stepien, Y Wang, ... Proceedings of the National Academy of Sciences 117 (12), 6559-6570, 2020 | 27 | 2020 |
| A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3 X Shen, L Zhao, P Chen, Y Gong, D Liu, X Zhang, L Dai, Q Sun, J Lou, ... Journal of Biological Chemistry 294 (46), 17471-17486, 2019 | 27 | 2019 |
| Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH W Huang, Z Liu, F Yang, H Zhou, X Yong, X Yang, Y Zhou, L Xue, ... Proceedings of the National Academy of Sciences 116 (45), 22598-22608, 2019 | 23 | 2019 |
