| IL-15 trans-presentation promotes human NK cell development and differentiation in vivo ND Huntington, N Legrand, NL Alves, B Jaron, K Weijer, A Plet, E Corcuff, ... Journal of Experimental Medicine 206 (1), 25-34, 2009 | 634 | 2009 |
| IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation E Mortier, T Woo, R Advincula, S Gozalo, A Ma The Journal of experimental medicine 205 (5), 1213-1225, 2008 | 370 | 2008 |
| Soluble interleukin-15 receptor α (IL-15Rα)-sushi as a selective and potent agonist of IL-15 action through IL-15Rβ/γ: hyperagonist IL-15· IL-15Rα fusion proteins E Mortier, A Quéméner, P Vusio, I Lorenzen, Y Boublik, J Grötzinger, ... Journal of Biological Chemistry 281 (3), 1612-1619, 2006 | 346 | 2006 |
| Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20 EE Turer, RM Tavares, E Mortier, O Hitotsumatsu, R Advincula, B Lee, ... The Journal of experimental medicine 205 (2), 451-464, 2008 | 324 | 2008 |
| Macrophage-and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets E Mortier, R Advincula, L Kim, S Chmura, J Barrera, B Reizis, BA Malynn, ... Immunity 31 (5), 811-822, 2009 | 247 | 2009 |
| Natural, proteolytic release of a soluble form of human IL-15 receptor α-chain that behaves as a specific, high affinity IL-15 antagonist E Mortier, J Bernard, A Plet, Y Jacques The Journal of Immunology 173 (3), 1681-1688, 2004 | 181 | 2004 |
| Identification of an interleukin-15α receptor-binding site on human interleukin-15 J Bernard, C Harb, E Mortier, A Quéméner, RH Meloen, ... Journal of Biological Chemistry 279 (23), 24313-24322, 2004 | 104 | 2004 |
| Syndecan-1 regulates the biological activities of interleukin-34 AI Segaliny, R Brion, E Mortier, M Maillasson, M Cherel, Y Jacques, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (5), 1010-1021, 2015 | 97 | 2015 |
| The soluble α chain of interleukin-15 receptor: a proinflammatory molecule associated with tumor progression in head and neck cancer C Badoual, G Bouchaud, NEH Agueznay, E Mortier, S Hans, A Gey, ... Cancer research 68 (10), 3907-3914, 2008 | 94 | 2008 |
| IL-15Ralpha sushi domain—IL-15 fusion proteins Y Jacques, A Plet, E Mortier, A Quemener, P Vusio US Patent 10,358,477, 2019 | 84 | 2019 |
| IL-15. IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells F Tamzalit, I Barbieux, A Plet, J Heim, S Nedellec, S Morisseau, ... Proceedings of the National Academy of Sciences 111 (23), 8565-8570, 2014 | 83 | 2014 |
| Interleukin-15 and cancer: some solved and many unsolved questions. AB Fiore PF, Di Matteo S, Tumino N, Mariotti FR, Pietra G, Ottonello S ... J Immunother Cancer 8 (2), e001428, 2020 | 70 | 2020 |
| The exon-3-encoded domain of IL-15Rα contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Rα G Bouchaud, L Garrigue-Antar, V Solé, A Quéméner, Y Boublik, E Mortier, ... Journal of molecular biology 382 (1), 1-12, 2008 | 69 | 2008 |
| Regulation of CD4+NKG2D+ Th1 Cells in Patients with Metastatic Melanoma Treated with Sorafenib: Role of IL-15Rα and NKG2D Triggering AI Romero, N Chaput, V Poirier-Colame, S Rusakiewicz, N Jacquelot, ... Cancer research 74 (1), 68-80, 2014 | 55 | 2014 |
| IL-15 mutants having agonists/antagonists activity J Bernard, A Plet, Y Jacques, C Harb, A Quemener, E Mortier US Patent 7,858,081, 2010 | 47 | 2010 |
| Different dynamics of IL-15R activation following IL-15 cis-or trans-presentation H Perdreau, E Mortier, G Bouchaud, V Solé, Y Boublik, A Plet, Y Jacques European cytokine network 21 (4), 297, 2010 | 44 | 2010 |
| Interleukin-15 and its soluble receptor mediate the response to infliximab in patients with Crohn's disease G Bouchaud, E Mortier, M Flamant, I Barbieux, A Plet, JP Galmiche, ... Gastroenterology 138 (7), 2378-2387, 2010 | 40 | 2010 |
| Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway J Giron-Michel, S Azzi, K Khawam, E Mortier, A Caignard, A Devocelle, ... PloS one 7 (2), e31624, 2012 | 37 | 2012 |
| Docking of human interleukin‐15 to its specific receptor α chain: Correlation between molecular modeling and mutagenesis experimental data A Quemener, J Bernard, E Mortier, A Plet, Y Jacques, V Tran PROTEINS: Structure, Function, and Bioinformatics 65 (3), 623-636, 2006 | 33 | 2006 |
| IL-15 mutants having antagonist activity J Bernard, A Plet, Y Jacques, C Harb, A Quemener, E Mortier US Patent 9,493,533, 2016 | 30 | 2016 |
