Mutation-induced changes in the receptor-binding interface of the SARS-CoV-2 Delta variant B. 1.617. 2 and implications for immune evasion P Baral, N Bhattarai, ML Hossen, V Stebliankin, BS Gerstman, ... Biochemical and biophysical research communications 574, 14-19, 2021 | 85 | 2021 |
The genomic landscape across 474 surgically accessible epileptogenic human brain lesions JA López-Rivera, C Leu, M Macnee, J Khoury, L Hoffmann, R Coras, ... Brain 146 (4), 1342-1356, 2023 | 38 | 2023 |
Molecular mechanisms of pore formation and membrane disruption by the antimicrobial lantibiotic peptide Mutacin 1140 R Pokhrel, N Bhattarai, P Baral, BS Gerstman, JH Park, M Handfield, ... Physical Chemistry Chemical Physics 21 (23), 12530-12539, 2019 | 38 | 2019 |
Structural and dynamical differences in the spike protein RBD in the SARS-CoV-2 variants B. 1.1. 7 and B. 1.351 N Bhattarai, P Baral, BS Gerstman, PP Chapagain The Journal of Physical Chemistry B 125 (26), 7101-7107, 2021 | 37 | 2021 |
Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry KJ Wijesinghe, S Urata, N Bhattarai, EE Kooijman, BS Gerstman, ... Journal of Biological Chemistry 292 (15), 6108-6122, 2017 | 37 | 2017 |
Graphene-VP40 interactions and potential disruption of the Ebola virus matrix filaments R Pokhrel, N Bhattarai, KA Johnson, BS Gerstman, RV Stahelin, ... Biochemical and biophysical research communications 493 (1), 176-181, 2017 | 20 | 2017 |
Plasma membrane association facilitates conformational changes in the Marburg virus protein VP40 dimer N Bhattarai, BS Gerstman, RV Stahelin, PP Chapagain RSC advances 7 (37), 22741-22748, 2017 | 19 | 2017 |
Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly S Amiar, ML Husby, KJ Wijesinghe, S Angel, N Bhattarai, BS Gerstman, ... Journal of Biological Chemistry 296, 2021 | 16 | 2021 |
Cysteine mutations in the Ebolavirus matrix protein VP40 promote phosphatidylserine binding by increasing the flexibility of a lipid-binding loop KA Johnson, N Bhattarai, MR Budicini, CM LaBonia, SCB Baker, ... Viruses 13 (7), 1375, 2021 | 13 | 2021 |
Conformational Flexibility of the Protein–Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament E Pavadai, N Bhattarai, P Baral, RV Stahelin, PP Chapagain, ... The Journal of Physical Chemistry B 123 (43), 9045-9053, 2019 | 10 | 2019 |
Lipid II binding and transmembrane properties of various antimicrobial lanthipeptides R Pokhrel, N Bhattarai, P Baral, BS Gerstman, JH Park, M Handfield, ... Journal of Chemical Theory and Computation 18 (1), 516-525, 2021 | 9 | 2021 |
Mutation of hydrophobic residues in the C-terminal domain of the Marburg virus matrix protein VP40 disrupts trafficking to the plasma membrane KJ Wijesinghe, L McVeigh, ML Husby, N Bhattarai, J Ma, BS Gerstman, ... Viruses 12 (4), 482, 2020 | 7 | 2020 |
Role of k-loop cysteine residues in the marburg virus protein VP24–human Keap1 complex N Bhattarai, BS Gerstman, PP Chapagain ACS Omega 3 (12), 18639-18645, 2018 | 6 | 2018 |
PI(4,5)P2 Binding Sites in the Ebola Virus Matrix Protein Modulate Assembly and Budding KA Johnson, MR Budicini, S Urata, N Bhattarai, BS Gerstman, ... BioRxiv, 341248, 2018 | 6 | 2018 |
Ebola virus protein VP40 binding to Sec24c for transport to the plasma membrane N Bhattarai, E Pavadai, R Pokhrel, P Baral, ML Hossen, RV Stahelin, ... Proteins: Structure, Function, and Bioinformatics 90 (2), 340-350, 2022 | 5 | 2022 |
Detecting individual proteins and their surface charge variations in solution by the potentiometric nanoimpact method P Pandey, N Bhattarai, L Su, X Wang, F Leng, B Gerstman, PP Chapagain, ... ACS sensors 7 (2), 555-563, 2022 | 5 | 2022 |
PI (4, 5) P2 binding sites in the Ebola virus matrix protein VP40 modulate assembly and budding KA Johnson, MR Budicini, N Bhattarai, T Sharma, S Urata, BS Gerstman, ... Journal of lipid research 65 (3), 2024 | 3 | 2024 |
Potential disruption of Ebola virus matrix by graphene nano-sheets R Pokhrel, GC Jeevan, N Bhattarai, P Chapagain, B Gerstman Biophysical Journal 114 (3), 218a, 2018 | 2 | 2018 |
Distances from ligands as main predictive features for pathogenicity and functional effect of variants in NMDA receptors L Montanucci, T Brünger, N Bhattarai, CM Boßelmann, S Kim, JP Allen, ... medRxiv, 2024.05. 06.24306939, 2024 | | 2024 |
Impact of the AQP5 H173D mutation on H2O and CO2 permeability: Physiology and MD studies P Pandey, N Bhattarai, DK Wang, T Kowatz, E Shinn, E Tajkhorshid, ... Biophysical Journal 123 (3), 265a-266a, 2024 | | 2024 |