Organoid modeling of the tumor immune microenvironment JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ... Cell 175 (7), 1972-1988. e16, 2018 | 1200 | 2018 |
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis J Rosenbluh, D Nijhawan, AG Cox, X Li, JT Neal, EJ Schafer, TI Zack, ... Cell 151 (7), 1457-1473, 2012 | 845 | 2012 |
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture X Li, L Nadauld, A Ootani, DC Corney, RK Pai, O Gevaert, MA Cantrell, ... Nature medicine 20 (7), 769-777, 2014 | 454 | 2014 |
Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88 SE Cheesman, JT Neal, E Mittge, BM Seredick, K Guillemin Proceedings of the National Academy of Sciences 108 (supplement_1), 4570-4577, 2011 | 283 | 2011 |
Massively parallel assessment of human variants with base editor screens RE Hanna, M Hegde, CR Fagre, PC DeWeirdt, AK Sangree, Z Szegletes, ... Cell 184 (4), 1064-1080. e20, 2021 | 241 | 2021 |
H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model JT Neal, TS Peterson, ML Kent, K Guillemin Disease models & mechanisms 6 (3), 802-810, 2013 | 129 | 2013 |
Surfactant Protein A2 (SP-A2) Variants Expressed in CHO Cells Stimulate Phagocytosis of Pseudomonas aeruginosa More than Do SP-A1 Variants AN Mikerov, G Wang, TM Umstead, M Zacharatos, NJ Thomas, DS Phelps, ... Infection and immunity 75 (3), 1403-1412, 2007 | 91 | 2007 |
Organoids as models for neoplastic transformation JT Neal, CJ Kuo Annual Review of Pathology: Mechanisms of Disease 11 (1), 199-220, 2016 | 83 | 2016 |
Massively parallel phenotyping of coding variants in cancer with Perturb-seq O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ... Nature biotechnology 40 (6), 896-905, 2022 | 81 | 2022 |
Genome-wide analysis of somatic noncoding mutation patterns in cancer F Dietlein, AB Wang, C Fagre, A Tang, NJM Besselink, E Cuppen, C Li, ... Science 376 (6589), eabg5601, 2022 | 65 | 2022 |
An Atlas of Variant Effects to understand the genome at nucleotide resolution DM Fowler, DJ Adams, AL Gloyn, WC Hahn, DS Marks, LA Muffley, ... Genome Biology 24 (1), 147, 2023 | 51 | 2023 |
The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein L Chakrabarti, JT Neal, M Miles, RA Martinez, AC Smith, BL Sopher, ... Mammalian genome 17, 103-110, 2006 | 41 | 2006 |
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment JE Klomp, YS Lee, CM Goodwin, B Papke, JA Klomp, AM Waters, ... Cell reports 37 (9), 2021 | 24 | 2021 |
A genome-wide atlas of human cell morphology M Ramezani, J Bauman, A Singh, E Weisbart, J Yong, M Lozada, GP Way, ... bioRxiv, 2023 | 20 | 2023 |
Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila DW Reid, JB Muyskens, JT Neal, GW Gaddini, LY Cho, AM Wandler, ... Frontiers in Cellular and Infection Microbiology 2, 24, 2012 | 18 | 2012 |
Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutations O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ... Biorxiv, 2020.11. 16.383307, 2020 | 15 | 2020 |
Methods and compositions for massively parallel variant and small molecule phenotyping A Regev, P Thakore, J Doench, JT Neal, J Boehm, O Ursu US Patent App. 16/809,458, 2020 | 2 | 2020 |
Cancer Informatics in 2017: A New Beginning and a Bright Future JL Warner, DA Patt Yearbook of Medical Informatics 27 (01), 223-226, 2018 | 2 | 2018 |
Building a Genome-Wide Atlas of Cell Morphology J Neal Enabling Capabilities and Resources, 2024 | | 2024 |
Pseudo-labeling enhanced by privileged information and its application to in situ sequencing images M Haghighi, MC Cruz, E Weisbart, BA Cimini, A Singh, J Bauman, ... arXiv preprint arXiv:2306.15898, 2023 | | 2023 |