Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells M Daher, R Basar, E Gokdemir, N Baran, N Uprety, AK Nunez Cortes, ... Blood, The Journal of the American Society of Hematology 137 (5), 624-636, 2021 | 204 | 2021 |
14-3-3ζ turns TGF-β’s function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2 J Xu, S Acharya, O Sahin, Q Zhang, Y Saito, J Yao, H Wang, P Li, L Zhang, ... Cancer cell 27 (2), 177-192, 2015 | 193 | 2015 |
Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells H Shaim, M Shanley, R Basar, M Daher, J Gumin, DB Zamler, N Uprety, ... The Journal of Clinical Investigation 131 (14), 2021 | 167 | 2021 |
KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape Y Li, R Basar, G Wang, E Liu, JS Moyes, L Li, LN Kerbauy, N Uprety, ... Nature medicine 28 (10), 2133-2144, 2022 | 83 | 2022 |
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors: a phase 1/2 trial D Marin, Y Li, R Basar, H Rafei, M Daher, J Dou, V Mohanty, M Dede, ... Nature medicine 30 (3), 772-784, 2024 | 78 | 2024 |
Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer. YD Acharya S, Yao J, Li P, Zhang C, Lowery FJ, Zhang Q, Guo H, Qu J, Yang F ... Cancer Research 79 (16), 4211-4226, 2019 | 62 | 2019 |
Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering L Li, V Mohanty, J Dou, Y Huang, PP Banerjee, Q Miao, JG Lohr, ... Science Advances 9 (30), eadd6997, 2023 | 42 | 2023 |
GMP-compliant universal antigen presenting cells (uAPC) promote the metabolic fitness and antitumor activity of armored cord blood CAR-NK cells E Liu, SOT Ang, L Kerbauy, R Basar, I Kaur, M Kaplan, L Li, Y Tong, ... Frontiers in immunology 12, 626098, 2021 | 40 | 2021 |
Large-scale GMP-compliant CRISPR-Cas9–mediated deletion of the glucocorticoid receptor in multivirus-specific T cells R Basar, M Daher, N Uprety, E Gokdemir, A Alsuliman, E Ensley, G Ozcan, ... Blood advances 4 (14), 3357-3367, 2020 | 32 | 2020 |
Thyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cells A Das, S Acharya, KR Gottipati, JB McKnight, H Chandru, JL Alcorn, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 301 (4 …, 2011 | 31 | 2011 |
Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy R Basar, N Uprety, E Ensley, M Daher, K Klein, F Martinez, F Aung, ... Cell Reports 36 (3), 2021 | 30 | 2021 |
Metabolic reprogramming of GMP grade cord tissue derived mesenchymal stem cells enhances their suppressive potential in GVHD M Mendt, M Daher, R Basar, M Shanley, B Kumar, FL Wei Inng, S Acharya, ... Frontiers in immunology 12, 631353, 2021 | 21 | 2021 |
Downregulation of GLUT4 contributes to effective intervention of estrogen receptor-negative/HER2-overexpressing early stage breast disease progression by lapatinib S Acharya, J Xu, X Wang, S Jain, H Wang, Q Zhang, CC Chang, J Bower, ... American Journal of Cancer Research 6 (5), 981, 2016 | 19 | 2016 |
CD70 CAR NK cells in the treatment of multiple Myeloma P Lin, FCR Silva, P Lin, AL Gilbert, S Acharya, AKN Cortes, P Banerjee, ... Blood 142, 3463, 2023 | 5 | 2023 |
Targeting T-cell lymphoma using CD70-directed cord blood-derived CAR-NK cells H Rafei, R Basar, S Acharya, P Zhang, P Liu, SM Moseley, P Li, M Daher, ... Blood 142, 4811, 2023 | 2 | 2023 |
Targeting kinases for the treatment of cancer metastasis D Yu, F Lowery, C Zhang, S Acharya, P Li US Patent 11,406,643, 2022 | 2 | 2022 |
CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor M Daher, R Basar, E Gokdemir, N Baran, N Uprety, AK Nunez Cortes, ... bioRxiv, 2020.03. 29.014472, 2020 | 2 | 2020 |
Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD M Shanley, M Daher, J Dou, S Li, R Basar, H Rafei, M Dede, J Gumin, ... Cancer cell 42 (8), 1450-1466. e11, 2024 | 1 | 2024 |
CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis S Acharya, R Basar, M Daher, H Rafei, P Li, N Uprety, E Ensley, ... Cancer Discovery, OF1-OF22, 2024 | 1 | 2024 |
DAP10 Co-Stimulation Imparts Memory-like Features to CD5 Targeting Cord Blood Derived CAR-NK Cells R Basar, MD Daher, N Uprety, E Ensley, AK Nunez Cortes, S Acharya, ... Blood 142 (Supplement 1), 2089-2089, 2023 | 1 | 2023 |