Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: role of epigenetic histone modifications K Tikoo, G Patel, S Kumar, PA Karpe, M Sanghavi, V Malek, K Srinivasan Biochemical pharmacology 93 (3), 343-351, 2015 | 188 | 2015 |
Activation of angiotensin-converting enzyme 2 (ACE2) attenuates allergic airway inflammation in rat asthma model VS Dhawale, VR Amara, PA Karpe, V Malek, D Patel, K Tikoo Toxicology and applied pharmacology 306, 17-26, 2016 | 65 | 2016 |
Diminazene aceturate prevents nephropathy by increasing glomerular ACE2 and AT2 receptor expression in a rat model of type1 diabetes SK Goru, A Kadakol, V Malek, A Pandey, N Sharma, AB Gaikwad British journal of pharmacology 174 (18), 3118-3130, 2017 | 62 | 2017 |
Telmisartan and thiorphan combination treatment attenuates fibrosis and apoptosis in preventing diabetic cardiomyopathy V Malek, AB Gaikwad Cardiovascular Research 115 (2), 373-384, 2019 | 61 | 2019 |
Esculetin ameliorates hepatic fibrosis in high fat diet induced non-alcoholic fatty liver disease by regulation of FoxO1 mediated pathway A Pandey, P Raj, SK Goru, A Kadakol, V Malek, N Sharma, AB Gaikwad Pharmacological Reports 69 (4), 666-672, 2017 | 39 | 2017 |
Neprilysin inhibitors: a new hope to halt the diabetic cardiovascular and renal complications? V Malek, AB Gaikwad Biomedicine & Pharmacotherapy 90, 752-759, 2017 | 39 | 2017 |
Histone H2AK119 and H2BK120 mono-ubiquitination modulate SET7/9 and SUV39H1 in type 1 diabetes-induced renal fibrosis SK Goru, A Kadakol, A Pandey, V Malek, N Sharma, AB Gaikwad Biochemical Journal 473 (21), 3937-3949, 2016 | 39 | 2016 |
Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy V Malek, N Sharma, H Sankrityayan, AB Gaikwad Life Sciences 221, 159-167, 2019 | 37 | 2019 |
Differential regulation of angiotensin converting enzyme 2 and nuclear factor-κB by angiotensin II receptor subtypes in type 2 diabetic kidney A Pandey, SK Goru, A Kadakol, V Malek, AB Gaikwad Biochimie 118, 71-81, 2015 | 34 | 2015 |
Esculetin attenuates alterations in Ang II and acetylcholine mediated vascular reactivity associated with hyperinsulinemia and hyperglycemia A Kadakol, V Malek, SK Goru, A Pandey, S Bagal, AB Gaikwad Biochemical and Biophysical Research Communications 461 (2), 342-347, 2015 | 34 | 2015 |
Angiotensin II type 2 receptor and angiotensin-converting enzyme 2 mediate ischemic renal injury in diabetic and non-diabetic rats N Sharma, V Malek, SR Mulay, AB Gaikwad Life sciences 235, 116796, 2019 | 32 | 2019 |
Esculetin reverses histone H2A/H2B ubiquitination, H3 dimethylation, acetylation and phosphorylation in preventing type 2 diabetic cardiomyopathy A Kadakol, V Malek, SK Goru, A Pandey, AB Gaikwad Journal of functional foods 17, 127-136, 2015 | 29 | 2015 |
Histone acetylation regulates natriuretic peptides and neprilysin gene expressions in diabetic cardiomyopathy and nephropathy V Malek, N Sharma, AB Gaikwad Current molecular pharmacology 12 (1), 61-71, 2019 | 26 | 2019 |
H2AK119 monoubiquitination regulates Angiotensin II receptor mediated macrophage infiltration and renal fibrosis in type 2 diabetic rats A Pandey, SK Goru, A Kadakol, V Malek, N Sharma, AB Gaikwad Biochimie 131, 68-76, 2016 | 25 | 2016 |
Potential of renin-angiotensin-aldosterone system modulations in diabetic kidney disease: old players to new hope! V Malek, SV Suryavanshi, N Sharma, YA Kulkarni, SR Mulay, AB Gaikwad Reviews of physiology, biochemistry and pharmacology, 31-71, 2021 | 23 | 2021 |
FoxO1 inhibitors: the future medicine for metabolic disorders? A Pandey, GS Kumar, A Kadakol, V Malek, A Bhanudas Gaikwad Current diabetes reviews 12 (3), 223-230, 2016 | 22 | 2016 |
Esculetin ameliorates insulin resistance and type 2 diabetic nephropathy through reversal of histone H3 acetylation and H2A lysine 119 monoubiquitination A Kadakol, V Malek, SK Goru, A Pandey, N Sharma, AB Gaikwad Journal of functional foods 35, 256-266, 2017 | 20 | 2017 |
Simultaneous inhibition of neprilysin and activation of ACE2 prevented diabetic cardiomyopathy V Malek, N Sharma, AB Gaikwad Pharmacological Reports 71 (5), 958-967, 2019 | 18 | 2019 |
Insulin sensitizing and cardioprotective effects of Esculetin and Telmisartan combination by attenuating Ang II mediated vascular reactivity and cardiac fibrosis A Kadakol, A Pandey, SK Goru, V Malek, AB Gaikwad European Journal of Pharmacology 765, 591-597, 2015 | 15 | 2015 |
Telmisartan and esculetin combination ameliorates type 2 diabetic cardiomyopathy by reversal of H3, H2A, and H2B histone modifications A Kadakol, V Malek, SK Goru, A Pandey, AB Gaikwad Indian Journal of Pharmacology 49 (5), 348-356, 2017 | 14 | 2017 |