关注
Dr Vajir Malek
Dr Vajir Malek
Ph.D. (Pharmacology)
在 coh.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: role of epigenetic histone modifications
K Tikoo, G Patel, S Kumar, PA Karpe, M Sanghavi, V Malek, K Srinivasan
Biochemical pharmacology 93 (3), 343-351, 2015
1882015
Activation of angiotensin-converting enzyme 2 (ACE2) attenuates allergic airway inflammation in rat asthma model
VS Dhawale, VR Amara, PA Karpe, V Malek, D Patel, K Tikoo
Toxicology and applied pharmacology 306, 17-26, 2016
652016
Diminazene aceturate prevents nephropathy by increasing glomerular ACE2 and AT2 receptor expression in a rat model of type1 diabetes
SK Goru, A Kadakol, V Malek, A Pandey, N Sharma, AB Gaikwad
British journal of pharmacology 174 (18), 3118-3130, 2017
622017
Telmisartan and thiorphan combination treatment attenuates fibrosis and apoptosis in preventing diabetic cardiomyopathy
V Malek, AB Gaikwad
Cardiovascular Research 115 (2), 373-384, 2019
612019
Esculetin ameliorates hepatic fibrosis in high fat diet induced non-alcoholic fatty liver disease by regulation of FoxO1 mediated pathway
A Pandey, P Raj, SK Goru, A Kadakol, V Malek, N Sharma, AB Gaikwad
Pharmacological Reports 69 (4), 666-672, 2017
392017
Neprilysin inhibitors: a new hope to halt the diabetic cardiovascular and renal complications?
V Malek, AB Gaikwad
Biomedicine & Pharmacotherapy 90, 752-759, 2017
392017
Histone H2AK119 and H2BK120 mono-ubiquitination modulate SET7/9 and SUV39H1 in type 1 diabetes-induced renal fibrosis
SK Goru, A Kadakol, A Pandey, V Malek, N Sharma, AB Gaikwad
Biochemical Journal 473 (21), 3937-3949, 2016
392016
Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy
V Malek, N Sharma, H Sankrityayan, AB Gaikwad
Life Sciences 221, 159-167, 2019
372019
Differential regulation of angiotensin converting enzyme 2 and nuclear factor-κB by angiotensin II receptor subtypes in type 2 diabetic kidney
A Pandey, SK Goru, A Kadakol, V Malek, AB Gaikwad
Biochimie 118, 71-81, 2015
342015
Esculetin attenuates alterations in Ang II and acetylcholine mediated vascular reactivity associated with hyperinsulinemia and hyperglycemia
A Kadakol, V Malek, SK Goru, A Pandey, S Bagal, AB Gaikwad
Biochemical and Biophysical Research Communications 461 (2), 342-347, 2015
342015
Angiotensin II type 2 receptor and angiotensin-converting enzyme 2 mediate ischemic renal injury in diabetic and non-diabetic rats
N Sharma, V Malek, SR Mulay, AB Gaikwad
Life sciences 235, 116796, 2019
322019
Esculetin reverses histone H2A/H2B ubiquitination, H3 dimethylation, acetylation and phosphorylation in preventing type 2 diabetic cardiomyopathy
A Kadakol, V Malek, SK Goru, A Pandey, AB Gaikwad
Journal of functional foods 17, 127-136, 2015
292015
Histone acetylation regulates natriuretic peptides and neprilysin gene expressions in diabetic cardiomyopathy and nephropathy
V Malek, N Sharma, AB Gaikwad
Current molecular pharmacology 12 (1), 61-71, 2019
262019
H2AK119 monoubiquitination regulates Angiotensin II receptor mediated macrophage infiltration and renal fibrosis in type 2 diabetic rats
A Pandey, SK Goru, A Kadakol, V Malek, N Sharma, AB Gaikwad
Biochimie 131, 68-76, 2016
252016
Potential of renin-angiotensin-aldosterone system modulations in diabetic kidney disease: old players to new hope!
V Malek, SV Suryavanshi, N Sharma, YA Kulkarni, SR Mulay, AB Gaikwad
Reviews of physiology, biochemistry and pharmacology, 31-71, 2021
232021
FoxO1 inhibitors: the future medicine for metabolic disorders?
A Pandey, GS Kumar, A Kadakol, V Malek, A Bhanudas Gaikwad
Current diabetes reviews 12 (3), 223-230, 2016
222016
Esculetin ameliorates insulin resistance and type 2 diabetic nephropathy through reversal of histone H3 acetylation and H2A lysine 119 monoubiquitination
A Kadakol, V Malek, SK Goru, A Pandey, N Sharma, AB Gaikwad
Journal of functional foods 35, 256-266, 2017
202017
Simultaneous inhibition of neprilysin and activation of ACE2 prevented diabetic cardiomyopathy
V Malek, N Sharma, AB Gaikwad
Pharmacological Reports 71 (5), 958-967, 2019
182019
Insulin sensitizing and cardioprotective effects of Esculetin and Telmisartan combination by attenuating Ang II mediated vascular reactivity and cardiac fibrosis
A Kadakol, A Pandey, SK Goru, V Malek, AB Gaikwad
European Journal of Pharmacology 765, 591-597, 2015
152015
Telmisartan and esculetin combination ameliorates type 2 diabetic cardiomyopathy by reversal of H3, H2A, and H2B histone modifications
A Kadakol, V Malek, SK Goru, A Pandey, AB Gaikwad
Indian Journal of Pharmacology 49 (5), 348-356, 2017
142017
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