Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice JL McClain, V Grubišić, D Fried, RA Gomez-Suarez, GM Leinninger, ... Gastroenterology 146 (2), 497-507. e1, 2014 | 205 | 2014 |
Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 and nitric oxide IAM Brown, JL McClain, RE Watson, BA Patel, BD Gulbransen Cellular and molecular gastroenterology and hepatology 2 (1), 77-91, 2016 | 153 | 2016 |
Agonist-evoked Ca2+ signaling in enteric glia drives neural programs that regulate intestinal motility in mice JL McClain, DE Fried, BD Gulbransen Cellular and molecular gastroenterology and hepatology 1 (6), 631-645, 2015 | 114 | 2015 |
Enteric glia modulate macrophage phenotype and visceral sensitivity following inflammation V Grubišić, JL McClain, DE Fried, I Grants, P Rajasekhar, E Csizmadia, ... Cell reports 32 (10), 2020 | 113 | 2020 |
Doxycycline, a matrix metalloprotease inhibitor, reduces vascular remodeling and damage after cerebral ischemia in stroke-prone spontaneously hypertensive rats PW Pires, CT Rogers, JL McClain, HS Garver, GD Fink, AM Dorrance American Journal of Physiology-Heart and Circulatory Physiology 301 (1), H87-H97, 2011 | 81 | 2011 |
Improvement in Middle Cerebral Artery Structure and Endothelial Function in Stroke‐Prone Spontaneously Hypertensive Rats after Macrophage Depletion PW Pires, SS Girgla, JL McClain, NE Kaminski, N van Rooijen, ... Microcirculation 20 (7), 650-661, 2013 | 52 | 2013 |
Tempol, a superoxide dismutase mimetic, prevents cerebral vessel remodeling in hypertensive rats PW Pires, C Deutsch, JL McClain, CT Rogers, AML Dorrance Microvascular research 80 (3), 445-452, 2010 | 46 | 2010 |
The acute inhibition of enteric glial metabolism with fluoroacetate alters calcium signaling, hemichannel function, and the expression of key proteins JL McClain, BD Gulbransen Journal of Neurophysiology 117 (1), 365-375, 2017 | 37 | 2017 |
Tumor necrosis factor-α inhibition attenuates middle cerebral artery remodeling but increases cerebral ischemic damage in hypertensive rats PW Pires, SS Girgla, G Moreno, JL McClain, AM Dorrance American Journal of Physiology-Heart and Circulatory Physiology 307 (5 …, 2014 | 37 | 2014 |
Gastrointestinal neuroimmune disruption in a mouse model of Gulf War illness S Hernandez, DE Fried, V Grubišić, JL McClain, BD Gulbransen The FASEB Journal 33 (5), 6168, 2019 | 35 | 2019 |
The development of hypertension and hyperaldosteronism in a rodent model of life-long obesity CA Northcott, GD Fink, H Garver, JR Haywood, EL Laimon-Thomson, ... Endocrinology 153 (4), 1764-1773, 2012 | 32 | 2012 |
Histamine-dependent interactions between mast cells, glia, and neurons are altered following early-life adversity in mice and humans JL McClain, EA Mazzotta, N Maradiaga, N Duque-Wilckens, I Grants, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 319 (6 …, 2020 | 29 | 2020 |
Functional intraregional and interregional heterogeneity between myenteric glial cells of the colon and duodenum in mice L Seguella, JL McClain, G Esposito, BD Gulbransen Journal of Neuroscience 42 (46), 8694-8708, 2022 | 16 | 2022 |
LPAR1 regulates enteric nervous system function through glial signaling and contributes to chronic intestinal pseudo-obstruction MM Ahmadzai, JL McClain, C Dharshika, L Seguella, F Giancola, ... The Journal of Clinical Investigation 132 (4), 2022 | 16 | 2022 |
Temporary mineralocorticoid receptor antagonism during the development of hypertension improves cerebral artery dilation JL McClain, AM Dorrance Experimental Biology and Medicine 239 (5), 619-627, 2014 | 14 | 2014 |
Mineralocorticoid receptor antagonism prevents obesity‐induced cerebral artery remodeling and reduces white matter injury in rats PW Pires, JL McClain, SF Hayoz, AM Dorrance Microcirculation 25 (5), e12460, 2018 | 12 | 2018 |
Sirtuin-3 is expressed by enteric neurons but it does not play a major role in their regulation of oxidative stress RK Bubenheimer, IAM Brown, DE Fried, JL McClain, BD Gulbransen Frontiers in cellular neuroscience 10, 73, 2016 | 12 | 2016 |
Sexually Dimorphic Effects of Histamine Degradation by Enteric Glial Histamine N-Methyltransferase (HNMT) on Visceral Hypersensitivity JL McClain, W Morales-Soto, J Gonzales, V Parmar, EY Demireva, ... Biomolecules 13 (11), 1651, 2023 | 3 | 2023 |
BQ788 reveals glial ETB receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus E Mazzotta, I Grants, E Villalobos‐Hernandez, S Chaudhuri, JL McClain, ... British Journal of Pharmacology 180 (19), 2550-2576, 2023 | 3 | 2023 |
Activation of enteric glia contributes to enteric neuron death in inflammation I Brown, J McClain, B Patel, B Gulbransen The FASEB Journal 29, 654.1, 2015 | 2 | 2015 |