Nano-palladium is a cellular catalyst for in vivo chemistry. MA Miller, B Askevold, H Mikula, RH Kohler, D Pirovich, R Weissleder Nature Communications 8, 15906, 2017 | 250 | 2017 |
Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage JCT Carlson, H Mikula, R Weissleder Journal of the American Chemical Society 140 (10), 3603-3612, 2018 | 170 | 2018 |
Development and validation of a rapid multi‐biomarker liquid chromatography/tandem mass spectrometry method to assess human exposure to mycotoxins B Warth, M Sulyok, P Fruhmann, H Mikula, F Berthiller, R Schuhmacher, ... Rapid Communications in Mass Spectrometry 26 (13), 1533-1540, 2012 | 151 | 2012 |
Development of a 18F‐Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging C Denk, D Svatunek, T Filip, T Wanek, D Lumpi, J Fröhlich, C Kuntner, ... Angewandte Chemie International Edition 53 (36), 9655-9659, 2014 | 130 | 2014 |
Tracking emerging mycotoxins in food: development of an LC-MS/MS method for free and modified Alternaria toxins H Puntscher, ML Kütt, P Skrinjar, H Mikula, J Podlech, J Fröhlich, D Marko, ... Analytical and bioanalytical chemistry 410, 4481-4494, 2018 | 127 | 2018 |
Validated UPLC-MS/MS Methods To Quantitate Free and Conjugated Alternaria Toxins in Commercially Available Tomato Products and Fruit and Vegetable Juices … J Walravens, H Mikula, M Rychlik, S Asam, T Devos, E Njumbe Ediage, ... Journal of Agricultural and Food Chemistry 64 (24), 5101-5109, 2016 | 115 | 2016 |
Development and validation of an ultra-high-performance liquid chromatography tandem mass spectrometric method for the simultaneous determination of free and conjugated … J Walravens, H Mikula, M Rychlik, S Asam, EN Ediage, JD Di Mavungu, ... Journal of Chromatography A 1372, 91-101, 2014 | 110 | 2014 |
Design, Synthesis, and Evaluation of a Low-Molecular-Weight 11C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry C Denk, D Svatunek, S Mairinger, J Stanek, T Filip, D Matscheko, ... Bioconjugate Chemistry 27 (7), 1707-1712, 2016 | 91 | 2016 |
Glucuronidation of zearalenone, zeranol and four metabolites in vitro: Formation of glucuronides by various microsomes and human UDP‐glucuronosyltransferase … E Pfeiffer, A Hildebrand, H Mikula, M Metzler Molecular nutrition & food research 54 (10), 1468-1476, 2010 | 90 | 2010 |
Modular nanoparticulate prodrug design enables efficient treatment of solid tumors using bioorthogonal activation MA Miller, H Mikula, G Luthria, R Li, S Kronister, M Prytyskach, RH Kohler, ... ACS nano 12 (12), 12814-12826, 2018 | 87 | 2018 |
Practical and efficient large-scale preparation of dimethyldioxirane H Mikula, D Svatunek, D Lumpi, F Glöcklhofer, C Hametner, J Fröhlich Organic Process Research & Development 17 (2), 313-316, 2013 | 71 | 2013 |
Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer R Li, TSC Ng, SJ Wang, M Prytyskach, CB Rodell, H Mikula, RH Kohler, ... Nature nanotechnology 16 (7), 830-839, 2021 | 70 | 2021 |
Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging EJL Stéen, JT Jørgensen, K Johann, K Nørregaard, B Sohr, D Svatunek, ... ACS nano 14 (1), 568-584, 2019 | 70 | 2019 |
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry EJL Stéen, JT Jørgensen, C Denk, UM Battisti, K Nørregaard, PE Edem, ... ACS pharmacology & translational science 4 (2), 824-833, 2021 | 66 | 2021 |
Optimized near-IR fluorescent agents for in vivo imaging of Btk expression E Kim, KS Yang, RH Kohler, JM Dubach, H Mikula, R Weissleder Bioconjugate chemistry 26 (8), 1513-1518, 2015 | 63 | 2015 |
An integrated in silico/in vitro approach to assess the xenoestrogenic potential of Alternaria mycotoxins and metabolites L Dellafiora, B Warth, V Schmidt, G Del Favero, H Mikula, J Fröhlich, ... Food chemistry 248, 253-261, 2018 | 60 | 2018 |
Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions D Svatunek, N Houszka, TA Hamlin, FM Bickelhaupt, H Mikula Chemistry–A European Journal 25 (3), 754-758, 2019 | 55 | 2019 |
Uncovering the key role of distortion in bioorthogonal tetrazine tools that defy the reactivity/stability trade-off D Svatunek, M Wilkovitsch, L Hartmann, KN Houk, H Mikula Journal of the American Chemical Society 144 (18), 8171-8177, 2022 | 50 | 2022 |
Direct Cu-mediated aromatic 18 F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging R García-Vázquez, UM Battisti, JT Jørgensen, V Shalgunov, L Hvass, ... Chemical science 12 (35), 11668-11675, 2021 | 49 | 2021 |
A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes M Wilkovitsch, M Haider, B Sohr, B Herrmann, J Klubnick, R Weissleder, ... Journal of the American Chemical Society 142 (45), 19132-19141, 2020 | 45 | 2020 |