CD4+ CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-β–TGF-β receptor interactions in type 1 diabetes EA Green, L Gorelik, CM McGregor, EH Tran, RA Flavell Proceedings of the National Academy of Sciences 100 (19), 10878-10883, 2003 | 609 | 2003 |
TGF-β regulates in vivo expansion of Foxp3-expressing CD4+ CD25+ regulatory T cells responsible for protection against diabetes Y Peng, Y Laouar, MO Li, EA Green, RA Flavell Proceedings of the National Academy of Sciences 101 (13), 4572-4577, 2004 | 605 | 2004 |
Pancreatic lymph node-derived CD4+ CD25+ Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals EA Green, Y Choi, RA Flavell Immunity 16 (2), 183-191, 2002 | 384 | 2002 |
Local expression of TNFα in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens EA Green, EE Eynon, RA Flavell Immunity 9 (5), 733-743, 1998 | 246 | 1998 |
A dual role for TNF-α in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis U Christen, T Wolfe, U Möhrle, AC Hughes, E Rodrigo, EA Green, ... The Journal of Immunology 166 (12), 7023-7032, 2001 | 202 | 2001 |
Contribution of Fas to diabetes development AY Savinov, A Tcherepanov, EA Green, RA Flavell, AV Chervonsky Proceedings of the National Academy of Sciences 100 (2), 628-632, 2003 | 124 | 2003 |
The temporal importance of TNFα expression in the development of diabetes EA Green, RA Flavell Immunity 12 (5), 459-469, 2000 | 121 | 2000 |
Tumor necrosis factor‐a and the progression of diabetes in non‐obese diabetic mice EA Green, RA Flavell Immunological reviews 169 (1), 11-22, 1999 | 97 | 1999 |
B-cells promote intra-islet CD8+ cytotoxic T-cell survival to enhance type 1 diabetes GM Brodie, M Wallberg, P Santamaria, FS Wong, EA Green Diabetes 57 (4), 909-917, 2008 | 91 | 2008 |
Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development PJ Spence, EA Green Proceedings of the National Academy of Sciences 105 (3), 973-978, 2008 | 91 | 2008 |
TRANCE–RANK, a new signal pathway involved in lymphocyte development and T cell activation EA Green, RA Flavell The Journal of experimental medicine 189 (7), 1017, 1999 | 88 | 1999 |
Neonatal tumor necrosis factor α promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8+ T cells EA Green, FS Wong, K Eshima, C Mora, RA Flavell The Journal of experimental medicine 191 (2), 225, 2000 | 84 | 2000 |
Cost-effective analysis of candidate genes using htSNPs: a staged approach CE Lowe, JD Cooper, JM Chapman, BJ Barratt, RCJ Twells, EA Green, ... Genes & Immunity 5 (4), 301-305, 2004 | 59 | 2004 |
The initiation of autoimmune diabetes EA Green, RA Flavell Current opinion in immunology 11 (6), 663-669, 1999 | 51 | 1999 |
Protection of islet grafts through transforming growth factor-β–induced tolerogenic dendritic cells DC Thomas, FS Wong, P Zaccone, EA Green, M Wållberg Diabetes 62 (9), 3132-3142, 2013 | 49 | 2013 |
Abrogation of CD40–CD154 signaling impedes the homeostasis of thymic resident regulatory T cells by altering the levels of IL-2, but does not affect regulatory T cell development SM Cuss, EA Green The Journal of Immunology 189 (4), 1717-1725, 2012 | 28 | 2012 |
A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin‐dependent diabetes mellitus in the non‐obese diabetic mouse K Eshima, C Mora, FS Wong, EA Green, IS Grewal, RA Flavell International immunology 15 (3), 351-357, 2003 | 22 | 2003 |
CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes CM McGregor, SP Schoenberger, EA Green Proceedings of the National Academy of Sciences 101 (25), 9345-9350, 2004 | 21 | 2004 |
Expression and purification of nonglycosylated SIV proteins, and their use in induction and detection of SIV-specific immune responses T HANKE, C BOTTING, EA GREEN, PW SZAWLOWSKI, E RUD, ... AIDS research and human retroviruses 10 (6), 665-674, 1994 | 21 | 1994 |
An islet-specific pulse of TGF-β abrogates CTL function and promotes β cell survival independent of Foxp3+ T cells M Wållberg, FS Wong, EA Green The Journal of Immunology 186 (4), 2543-2551, 2011 | 19 | 2011 |