Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma L Ma, L Wang, SA Khatib, CW Chang, S Heinrich, DA Dominguez, ... Journal of hepatology 75 (6), 1397-1408, 2021 | 176 | 2021 |
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma MH Hung, JS Lee, C Ma, LP Diggs, S Heinrich, CW Chang, L Ma, ... Nature communications 12 (1), 1455, 2021 | 137 | 2021 |
Distinct subpopulations of head and neck cancer cells with different levels of intracellular reactive oxygen species exhibit diverse stemness, proliferation, and chemosensitivity CW Chang, YS Chen, SH Chou, CL Han, YJ Chen, CC Yang, CY Huang, ... Cancer research 74 (21), 6291-6305, 2014 | 107 | 2014 |
ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells CW Chang, YS Chen, YG Tsay, CL Han, YJ Chen, CC Yang, KF Hung, ... Cell death & disease 9 (2), 194, 2018 | 87 | 2018 |
MicroRNA-15a/16-1 prevents hepatocellular carcinoma by disrupting the communication between Kupffer cells and regulatory T cells N Liu, CW Chang, CJ Steer, XW Wang, G Song Gastroenterology 162 (2), 575-589, 2022 | 44 | 2022 |
HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling JFL Yu-Syuan Chen,*, Ching-Wen Chang,*, Yeou-Guang Tsay, Liu-Ying Huang, Yi ... Theranostics, 2018 | 41 | 2018 |
Roles of mitochondria in liver cancer stem cells XWW Ching-Wen Chang, Jeng-Fan Lo Differentiation, 2019 | 27 | 2019 |
Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death CW Chang, CC Chen, MJ Wu, YS Chen, CC Chen, SJ Sheu, TW Lin, ... Evidence‐Based Complementary and Alternative Medicine 2013 (1), 946451, 2013 | 25 | 2013 |
Determination of pyruvate metabolic fates modulates head and neck tumorigenesis TY Chen, YT Hsieh, JM Huang, CJ Liu, LT Chuang, PC Huang, TY Kuo, ... Neoplasia 21 (7), 641-652, 2019 | 24 | 2019 |
Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models D Feng, X Xiang, Y Guan, A Guillot, H Lu, C Chang, Y He, H Wang, H Pan, ... The Journal of Clinical Investigation 133 (15), 2023 | 23 | 2023 |
Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and src activity using an active component of … Ching-Wen Chang, Yu-Syuan Chen, Chien-Chih Chen, Ik-On Chan, Chin-Chu Chen ... oncotarget, 2016 | 19 | 2016 |
Lyophilized particles and ethanolic extracts of Antrodia cinnamomea mycelia suppress the tumorigenicity of head and neck cancer cells in vivo CW Chang, YS Chen, CC Chen, CC Chen, SJ Sheu, T Lin, TC Lee, JF Lo BioMedicine 4 (4), 26, 2014 | 10 | 2014 |
Loss of Tid1/DNAJA3 co-chaperone promotes progression and recurrence of hepatocellular carcinoma after surgical resection: a novel model to stratify risk of recurrence KY Chen, YH Huang, WH Teo, CW Chang, YS Chen, YC Yeh, CJ Lee, ... Cancers 13 (1), 138, 2021 | 7 | 2021 |
Single-cell atlas of tumor clonal evolution in liver cancer L Ma, L Wang, CW Chang, S Heinrich, D Dominguez, M Forgues, ... bioRxiv, 2020.08. 18.254748, 2020 | 7 | 2020 |
Purine anabolism creates therapeutic vulnerability in hepatocellular carcinoma through m6A-mediated epitranscriptomic regulation MH Hung, CW Chang, KC Wang, J Chaisaingmongkol, M Ruchirawat, ... Hepatology 78 (5), 1462-1477, 2023 | 4 | 2023 |
Pyruvate kinase differentially alters metabolic signatures during head and neck carcinogenesis PC Huang, CW Chang, YC Lin, CY Chen, TY Chen, LT Chuang, CJ Liu, ... International Journal of Molecular Sciences 24 (23), 16639, 2023 | 2 | 2023 |
A genetic basis of mitochondrial DNAJA3 in nonalcoholic steatohepatitis-related hepatocellular carcinoma Hepatology, 2023 | 2 | 2023 |
Potential hepatic lipid markers associated with nonalcoholic steatohepatitis and fibrosis in morbid obesity patients HC Wu, YR Hsieh, W Wang, CW Chang, IW Chang, CL Chen, CC Chang, ... Journal of Clinical Medicine 12 (11), 3730, 2023 | 1 | 2023 |
A compendium of co-regulated mitoribosomal proteins in pan-cancer uncovers collateral defective events in tumor malignancy CW Chang, Z Wei, SR Durell, L Ma, M Forgues, XW Wang Iscience 25 (10), 2022 | 1 | 2022 |
Mitochondrial-associated DNAJA3 variant and its role in NASH-driven hepatocellular carcinoma Y Shiode, CW Chang, XW Wang Cancer Research 84 (6_Supplement), 1693-1693, 2024 | | 2024 |