Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines SG Patel, EJ Sayers, L He, R Narayan, TL Williams, EM Mills, ... Scientific reports 9 (1), 6298, 2019 | 219 | 2019 |
Unraveling the role of protein dynamics in dihydrofolate reductase catalysis LYP Luk, J Javier Ruiz-Pernia, WM Dawson, M Roca, EJ Loveridge, ... Proceedings of the National Academy of Sciences 110 (41), 16344-16349, 2013 | 149 | 2013 |
Mechanistic studies on norcoclaurine synthase of benzylisoquinoline alkaloid biosynthesis: an enzymatic Pictet− Spengler reaction LYP Luk, S Bunn, DK Liscombe, PJ Facchini, ME Tanner Biochemistry 46 (35), 10153-10161, 2007 | 148 | 2007 |
Using genetically incorporated unnatural amino acids to control protein functions in mammalian cells AR Nödling, LA Spear, TL Williams, LYP Luk, YH Tsai Essays in biochemistry 63 (2), 237-266, 2019 | 98 | 2019 |
A cope rearrangement in the reaction catalyzed by dimethylallyltryptophan synthase? LYP Luk, Q Qian, ME Tanner Journal of the American Chemical Society 133 (32), 12342-12345, 2011 | 93 | 2011 |
Mechanism of dimethylallyltryptophan synthase: evidence for a dimethylallyl cation intermediate in an aromatic prenyltransferase reaction LYP Luk, ME Tanner Journal of the American Chemical Society 131 (39), 13932-13933, 2009 | 88 | 2009 |
Increased Dynamic Effects in a Catalytically Compromised Variant of Escherichia coli Dihydrofolate Reductase JJ Ruiz-Pernia, LYP Luk, R García-Meseguer, S Martí, EJ Loveridge, ... Journal of the American Chemical Society 135 (49), 18689-18696, 2013 | 69 | 2013 |
Condensation of 2-((alkylthio)(aryl) methylene) malononitrile with 1, 2-aminothiol as a novel bioorthogonal reaction for site-specific protein modification and peptide cyclization X Zheng, Z Li, W Gao, X Meng, X Li, LYP Luk, Y Zhao, YH Tsai, C Wu Journal of the American Chemical Society 142 (11), 5097-5103, 2020 | 56 | 2020 |
Protein motions and dynamic effects in enzyme catalysis LYP Luk, EJ Loveridge, RK Allemann Physical Chemistry Chemical Physics 17 (46), 30817-30827, 2015 | 56 | 2015 |
Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes AR Nödling, EM Mills, X Li, D Cardella, EJ Sayers, SH Wu, AT Jones, ... Chemical Communications 56 (34), 4672-4675, 2020 | 49 | 2020 |
Reactivity and selectivity of iminium organocatalysis improved by a protein host AR Nödling, K Świderek, R Castillo, JW Hall, A Angelastro, LC Morrill, ... Angewandte Chemie 130 (38), 12658-12662, 2018 | 47 | 2018 |
Approaches for peptide and protein cyclisation HC Hayes, LYP Luk, YH Tsai Organic & biomolecular chemistry 19 (18), 3983-4001, 2021 | 46 | 2021 |
Comparative biological evaluation and G-quadruplex interaction studies of two new families of organometallic gold (I) complexes featuring N-heterocyclic carbene and alkynyl ligands SM Meier-Menches, B Aikman, D Döllerer, WT Klooster, SJ Coles, N Santi, ... Journal of Inorganic Biochemistry 202, 110844, 2020 | 46 | 2020 |
Use of an asparaginyl endopeptidase for chemo-enzymatic peptide and protein labeling TMS Tang, D Cardella, AJ Lander, X Li, JS Escudero, YH Tsai, LYP Luk Chemical science 11 (23), 5881-5888, 2020 | 44 | 2020 |
Chemical ligation and isotope labeling to locate dynamic effects during catalysis by dihydrofolate reductase LYP Luk, JJ Ruiz‐Pernía, AS Adesina, EJ Loveridge, I Tuñón, V Moliner, ... Angewandte Chemie 127 (31), 9144-9148, 2015 | 43 | 2015 |
Protein Isotope Effects in Dihydrofolate Reductase From Geobacillus stearothermophilus Show Entropic–Enthalpic Compensatory Effects on the Rate Constant LYP Luk, JJ Ruiz-Pernía, WM Dawson, EJ Loveridge, I Tuñón, V Moliner, ... Journal of the American Chemical Society 136 (49), 17317-17323, 2014 | 39 | 2014 |
A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number A Angelastro, WM Dawson, LYP Luk, RK Allemann ACS Catalysis 7 (2), 1025-1029, 2017 | 33 | 2017 |
Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases LYP Luk, EJ Loveridge, RK Allemann Journal of the American Chemical Society 136 (19), 6862-6865, 2014 | 31 | 2014 |
Minimization of dynamic effects in the evolution of dihydrofolate reductase JJ Ruiz-Pernía, E Behiry, LYP Luk, EJ Loveridge, I Tunón, V Moliner, ... Chemical Science 7 (5), 3248-3255, 2016 | 29 | 2016 |
D‐peptide and d‐protein technology: recent advances, challenges, and opportunities AJ Lander, Y Jin, LYP Luk ChemBioChem 24 (4), e202200537, 2023 | 28 | 2023 |