Regulation of alternative splicing by histone modifications RF Luco, Q Pan, K Tominaga, BJ Blencowe, OM Pereira-Smith, T Misteli Science 327 (5968), 996-1000, 2010 | 1241 | 2010 |
Epigenetics in alternative pre-mRNA splicing RF Luco, M Allo, IE Schor, AR Kornblihtt, T Misteli Cell 144 (1), 16-26, 2011 | 930 | 2011 |
A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature I Gonzalez, R Munita, E Agirre, TA Dittmer, K Gysling, T Misteli, RF Luco Nature structural & molecular biology 22 (5), 370-376, 2015 | 287 | 2015 |
IA1 is NGN3‐dependent and essential for differentiation of the endocrine pancreas G Mellitzer, S Bonné, RF Luco, M Van De Casteele, N Lenne‐Samuel, ... The EMBO journal 25 (6), 1344-1352, 2006 | 222 | 2006 |
Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas MA Maestro, SF Boj, RF Luco, CE Pierreux, J Cabedo, JM Servitja, ... Human molecular genetics 12 (24), 3307-3314, 2003 | 196 | 2003 |
More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation RF Luco, T Misteli Current opinion in genetics & development 21 (4), 366-372, 2011 | 159 | 2011 |
Distinct roles of HNF1 Β, HNF1 α, and HNF4 α in regulating pancreas development, Β-cell function and growth MA Maestro, C Cardalda, SF Boj, RF Luco, JM Servitja, J Ferrer Development of the Pancreas and Neonatal Diabetes 12, 33-45, 2007 | 144 | 2007 |
SETDB1-dependent heterochromatin stimulates alternative lengthening of telomeres M Gauchier, S Kan, A Barral, S Sauzet, E Agirre, E Bonnell, N Saksouk, ... Science advances 5 (5), eaav3673, 2019 | 87 | 2019 |
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition E Agirre, AJ Oldfield, N Bellora, A Segelle, RF Luco Nature communications 12 (1), 682, 2021 | 63 | 2021 |
A conditional model reveals that induction of hepatocyte nuclear factor-1α in Hnf1α-null mutant β-cells can activate silenced genes postnatally, whereas overexpression is … RF Luco, MA Maestro, N del Pozo, WM Philbrick, PP de la Ossa, J Ferrer Diabetes 55 (8), 2202-2211, 2006 | 26 | 2006 |
Targeted deficiency of the transcriptional activator Hnf1α alters subnuclear positioning of its genomic targets RF Luco, MA Maestro, N Sadoni, D Zink, J Ferrer PLoS genetics 4 (5), e1000079, 2008 | 23 | 2008 |
IRFinder-S: a comprehensive suite to discover and explore intron retention C Lorenzi, S Barriere, K Arnold, RF Luco, AJ Oldfield, W Ritchie Genome Biology 22, 1-13, 2021 | 21 | 2021 |
Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing A Segelle, Y Nunez-Alvarez, AJ Oldfield, KM Webb, P Voigt, RF Luco Cell Reports 38 (7), 2022 | 20 | 2022 |
A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants JP Villemin, C Lorenzi, MS Cabrillac, A Oldfield, W Ritchie, RF Luco BMC biology 19, 1-19, 2021 | 20 | 2021 |
A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development SK Sahu, E Agirre, M Inayatullah, A Mahesh, N Tiwari, DP Lavin, A Singh, ... Nature Cell Biology 24 (8), 1265-1277, 2022 | 18 | 2022 |
Retrotransposons jump into alternative-splicing regulation via a long noncoding RNA RF Luco Nature Structural & Molecular Biology 23 (11), 952-954, 2016 | 9 | 2016 |
A CRISPR-dCas13 RNA-editing tool to study alternative splicing Y Núñez-Álvarez, T Espie--Caullet, G Buhagiar, A Rubio-Zulaika, ... bioRxiv, 2022.05. 24.493209, 2022 | 4 | 2022 |
The non-coding genome: a universe in expansion for fine-tuning the coding world RF Luco Genome biology 14, 1-3, 2013 | 4 | 2013 |
Chromatin immunoprecipitation using isolated islets of Langerhans M Párrizas, SF Boj, RF Luco, MA Maestro, J Ferrer Diabetes Mellitus: Methods and Protocols, 61-71, 2003 | 4 | 2003 |
Histone marks are drivers of the splicing changes necessary for an epithelial-to-mesenchymal transition A Segelle, Y Núñez-Álvarez, AJ Oldfield, KM Webb, P Voigt, RF Luco bioRxiv, 2021.05. 04.442453, 2021 | 1 | 2021 |